Detailed information NTG0097807

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: R8619_RS08430
• Genome accession: NZ_AP026918
• Coordinates: 1645457..1646116 (+)
• Length: 219 a.a.
• NCBI ID: WP_000565606.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700009
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1640457..1651116

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8619_RS08405 (PC0009_16580)	-	1640762..1641079 (-)	318	WP_001151646.1	PTS sugar transporter subunit IIB	-
R8619_RS08410 (PC0009_16590)	-	1641094..1641990 (-)	897	WP_000825665.1	PEP phosphonomutase	-
R8619_RS08415 (PC0009_16600)	-	1641987..1643255 (-)	1269	WP_000413337.1	PTS sugar transporter subunit IIC	-
R8619_RS08420 (PC0009_16610)	-	1643535..1644713 (+)	1179	WP_000175879.1	ROK family transcriptional regulator	-
R8619_RS08425 (PC0009_16620)	-	1644941..1645387 (-)	447	WP_000155423.1	GNAT family N-acetyltransferase	-
R8619_RS08430 (PC0009_16630)	cclA/cilC	1645457..1646116 (+)	660	WP_000565606.1	A24 family peptidase	Machinery gene
R8619_RS08435 (PC0009_16640)	trpA	1646088..1646864 (-)	777	WP_001126993.1	tryptophan synthase subunit alpha	-
R8619_RS08440 (PC0009_16650)	trpB	1646857..1648080 (-)	1224	WP_000331298.1	tryptophan synthase subunit beta	-
R8619_RS08445 (PC0009_16660)	-	1648058..1648657 (-)	600	WP_000169872.1	phosphoribosylanthranilate isomerase	-
R8619_RS08450 (PC0009_16670)	trpC	1648644..1649411 (-)	768	WP_000076545.1	indole-3-glycerol phosphate synthase TrpC	-
R8619_RS08455 (PC0009_16680)	trpD	1649408..1650412 (-)	1005	WP_000658684.1	anthranilate phosphoribosyltransferase	-
R8619_RS08460 (PC0009_16690)	-	1650423..1650989 (-)	567	WP_000601921.1	aminodeoxychorismate/anthranilate synthase component II	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24860.94 Da
• Isoelectric Point: 7.3241

>NTDB_id=97807 R8619_RS08430 WP_000565606.1 1645457..1646116(+) (cclA/cilC) [Streptococcus pneumoniae strain PZ900700009]
MIDIYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLHPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLFYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=97807 R8619_RS08430 WP_000565606.1 1645457..1646116(+) (cclA/cilC) [Streptococcus pneumoniae strain PZ900700009]
ATGATTGATATTTATTTTTTTCTTGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCATCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGTTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae TIGR4	96.347	100	0.963
cclA/cilC	Streptococcus pneumoniae Rx1	95.89	100	0.959
cclA/cilC	Streptococcus pneumoniae D39	95.89	100	0.959
cclA/cilC	Streptococcus pneumoniae R6	95.89	100	0.959
cclA/cilC	Streptococcus mitis SK321	92.694	100	0.927
cclA/cilC	Streptococcus mitis NCTC 12261	86.758	100	0.868