Detailed information NTG0097637

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: R8522_RS04670
• Genome accession: NZ_AP026916
• Coordinates: 912328..913281 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain PZ900700006
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 907328..918281

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8522_RS04645	rpmG	908071..908220 (+)	150	WP_001810029.1	50S ribosomal protein L33	-
R8522_RS04650 (PC0006_09440)	secG	908260..908493 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
R8522_RS04655 (PC0006_09450)	rnr	908595..910949 (+)	2355	WP_054367309.1	ribonuclease R	-
R8522_RS04660 (PC0006_09460)	smpB	910912..911379 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
R8522_RS04665 (PC0006_09470)	tehB	911395..912255 (+)	861	WP_000413763.1	SAM-dependent methyltransferase TehB	-
R8522_RS04670 (PC0006_09480)	coiA	912328..913281 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
R8522_RS04675 (PC0006_09490)	pepF	913300..915102 (+)	1803	WP_000244135.1	oligoendopeptidase F	Regulator
R8522_RS04680 (PC0006_09500)	-	915104..915817 (+)	714	WP_000230399.1	O-methyltransferase	-
R8522_RS04685 (PC0006_09510)	prsA	915884..916825 (+)	942	WP_000727952.1	peptidylprolyl isomerase PrsA	-
R8522_RS04690 (PC0006_09520)	-	916944..917285 (-)	342	Protein_932	transposase	-
R8522_RS04695	-	917698..917793 (+)	96	Protein_933	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=97637 R8522_RS04670 WP_000495909.1 912328..913281(+) (coiA) [Streptococcus pneumoniae strain PZ900700006]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=97637 R8522_RS04670 WP_000495909.1 912328..913281(+) (coiA) [Streptococcus pneumoniae strain PZ900700006]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435