Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   ACM3H0_RS11215 Genome accession   NZ_CP180685
Coordinates   2149492..2151465 (-) Length   657 a.a.
NCBI ID   WP_000034617.1    Uniprot ID   Q8E2R5
Organism   Streptococcus agalactiae strain M14     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2144492..2156465
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACM3H0_RS11190 (ACM3H0_11190) recA 2144501..2145640 (-) 1140 WP_001085741.1 recombinase RecA Machinery gene
  ACM3H0_RS11195 (ACM3H0_11195) cinA 2145714..2146973 (-) 1260 WP_001200978.1 competence/damage-inducible protein A Machinery gene
  ACM3H0_RS11200 (ACM3H0_11200) - 2147062..2147613 (-) 552 WP_000817341.1 DNA-3-methyladenine glycosylase I -
  ACM3H0_RS11205 (ACM3H0_11205) ruvA 2147636..2148226 (-) 591 WP_000272487.1 Holliday junction branch migration protein RuvA Machinery gene
  ACM3H0_RS11210 (ACM3H0_11210) - 2148228..2149460 (-) 1233 WP_000657476.1 MDR family MFS transporter -
  ACM3H0_RS11215 (ACM3H0_11215) hexB 2149492..2151465 (-) 1974 WP_000034617.1 DNA mismatch repair endonuclease MutL Machinery gene
  ACM3H0_RS11220 (ACM3H0_11220) - 2151691..2151894 (+) 204 WP_000191849.1 cold-shock protein -
  ACM3H0_RS11225 (ACM3H0_11225) hexA 2151951..2154527 (-) 2577 WP_001118377.1 DNA mismatch repair protein MutS Machinery gene
  ACM3H0_RS11230 (ACM3H0_11230) argR 2154584..2155021 (-) 438 WP_001033152.1 arginine repressor -

Sequence

Protein


Download         Length: 657 a.a.        Molecular weight: 73758.93 Da        Isoelectric Point: 5.4718

>NTDB_id=976078 ACM3H0_RS11215 WP_000034617.1 2149492..2151465(-) (hexB) [Streptococcus agalactiae strain M14]
MSKIIELPDILANQIAAGEVVERPSSVVKELVENAIDAGSSQITIEVEESGLKKIQITDNGEGMTSEDAVLSLRRHATSK
IKSQSDLFRIRTLGFRGEALPSIASISLMTIKTATEQGKQGTLLVAKGGNIEKQEVVSSPRGTKILVENLFFNTPARLKY
MKSLQSELAHIIDIVNRLSLAHPEVAFTLINDGKEMTKTSGTGDLRQAIAGIYGLNTAKKMIEISNADLDFEISGYVSLP
ELTRANRNYITLLINGRYIKNFLLNRSILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKERELMSLIST
AISESLKQYDLIPDALENLAKTSTRSVDKPIQTSFSLKQPGLYYDRAKNDFFIGADTVSEPIANFTNLDKSDGSVDNDVK
NSVNQGATQSPNIKYASRDQADSENFIHSQDYLSSKQSLNKLVEKLDSEESSTFPELEFFGQMHGTYLFAQGNGGLYIID
QHAAQERVKYEYYREKIGEVDNSLQQLLVPFLFEFSSSDFLQLQEKMSLLQDVGIFLEPYGNNTFILREHPIWMKEEEVE
SGIYEMCDMLLLTNEVSVKKYRAELAIMMSCKRSIKANHTLDDYSARHLLDQLAQCKNPYNCPHGRPVLVNFTKADMEKM
FKRIQENHTSLRDLGKY

Nucleotide


Download         Length: 1974 bp        

>NTDB_id=976078 ACM3H0_RS11215 WP_000034617.1 2149492..2151465(-) (hexB) [Streptococcus agalactiae strain M14]
TTGTCTAAAATTATTGAATTACCGGATATATTAGCTAACCAGATTGCTGCTGGTGAGGTTGTTGAAAGGCCTAGTAGCGT
CGTTAAAGAATTAGTTGAAAATGCCATAGATGCAGGAAGTAGCCAAATTACCATAGAGGTTGAAGAATCTGGTCTTAAAA
AGATTCAAATAACGGATAACGGTGAAGGGATGACTAGTGAGGATGCCGTTCTCAGTTTACGACGTCACGCTACATCCAAA
ATCAAAAGCCAGAGTGACCTTTTTCGTATTCGGACCTTAGGTTTTCGTGGTGAAGCTCTACCATCAATCGCTTCGATTAG
TTTAATGACGATAAAAACAGCTACAGAGCAAGGGAAACAAGGGACGTTACTTGTTGCTAAAGGGGGAAACATTGAAAAAC
AGGAAGTTGTTTCAAGTCCTCGTGGAACAAAAATTTTAGTTGAAAATTTATTCTTTAACACGCCTGCCAGATTGAAATAC
ATGAAGAGTTTACAGTCTGAACTAGCTCATATTATTGATATTGTTAATAGACTCAGTCTAGCGCATCCGGAAGTTGCTTT
TACACTGATAAATGATGGTAAAGAAATGACTAAAACTAGTGGGACTGGCGATTTGAGACAGGCGATTGCAGGTATTTATG
GTTTAAATACTGCAAAAAAAATGATTGAGATTTCAAATGCAGATTTAGATTTTGAAATTTCGGGTTATGTAAGTTTGCCT
GAATTGACACGAGCTAACCGAAACTATATTACCCTATTAATTAACGGTCGTTACATTAAAAATTTTCTTTTGAACCGCTC
AATTCTAGATGGTTATGGTTCAAAGTTGATGGTTGGAAGATTTCCAATTGCTGTCATTGATATTCAGATAGATCCTTATC
TAGCAGATGTCAACGTTCATCCGACTAAGCAAGAGGTGAGAATTTCTAAGGAACGAGAATTAATGAGTTTAATAAGCACA
GCAATTTCTGAGAGTCTTAAACAATATGACTTGATTCCGGATGCTTTAGAGAATTTAGCTAAAACTAGTACCCGAAGTGT
AGATAAGCCTATACAAACAAGCTTCTCACTAAAACAGCCTGGTTTGTATTACGATAGGGCTAAAAATGACTTTTTTATAG
GTGCAGATACTGTATCTGAACCTATTGCTAACTTTACAAACCTTGACAAAAGTGACGGTTCAGTTGACAATGATGTAAAA
AACTCTGTTAATCAAGGAGCAACGCAGTCTCCTAATATAAAGTATGCTAGTAGAGATCAAGCTGATAGTGAGAACTTCAT
TCATTCTCAGGATTACCTTAGTAGTAAACAGTCACTTAACAAACTTGTTGAAAAATTAGATTCGGAAGAAAGTTCGACTT
TTCCAGAGCTCGAATTTTTTGGTCAAATGCATGGGACCTACTTATTTGCTCAAGGGAATGGTGGGTTGTATATTATTGAT
CAACATGCAGCTCAAGAGCGTGTAAAATACGAGTATTACCGTGAAAAGATAGGTGAGGTTGATAATAGTCTTCAACAATT
GTTAGTACCATTTCTATTTGAATTTTCAAGTTCAGATTTTCTTCAATTACAAGAAAAAATGTCATTATTACAAGATGTTG
GTATTTTCTTGGAACCGTATGGTAATAATACTTTCATTTTAAGGGAACATCCAATTTGGATGAAAGAAGAAGAGGTAGAG
TCTGGCATTTATGAAATGTGTGATATGTTGTTGCTCACTAATGAAGTATCAGTGAAAAAATATCGCGCAGAGTTGGCTAT
TATGATGTCTTGCAAGCGATCTATTAAAGCAAACCATACGCTAGACGATTACTCAGCACGTCATTTATTAGATCAGTTAG
CGCAATGTAAAAATCCTTATAATTGCCCTCATGGAAGACCTGTTTTAGTTAATTTTACAAAAGCTGATATGGAGAAAATG
TTTAAACGAATCCAAGAAAATCATACAAGCCTCAGGGATTTAGGAAAATATTGA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(458-601)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8E2R5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.044

100

0.693