Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   R8474_RS09590 Genome accession   NZ_AP026914
Coordinates   1879794..1880747 (-) Length   317 a.a.
NCBI ID   WP_000345127.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700003     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1874794..1885747
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8474_RS09560 (PC0003_18680) - 1875555..1876178 (-) 624 WP_000932657.1 hypothetical protein -
  R8474_RS09565 (PC0003_18690) jag 1876229..1877215 (-) 987 WP_000260018.1 RNA-binding cell elongation regulator Jag/EloR -
  R8474_RS09570 (PC0003_18700) - 1877234..1878058 (-) 825 WP_001832473.1 membrane protein insertase YidC -
  R8474_RS09575 (PC0003_18710) rnpA 1878033..1878404 (-) 372 WP_000739244.1 ribonuclease P protein component -
  R8474_RS09580 - 1878421..1878552 (-) 132 WP_000768904.1 hypothetical protein -
  R8474_RS09585 (PC0003_18720) - 1878553..1879743 (-) 1191 WP_000167769.1 acetate kinase -
  R8474_RS09590 (PC0003_18730) comYH 1879794..1880747 (-) 954 WP_000345127.1 class I SAM-dependent methyltransferase Machinery gene
  R8474_RS09595 - 1880808..1881402 (-) 595 Protein_1869 class I SAM-dependent methyltransferase -
  R8474_RS09600 (PC0003_18760) comGG/cglG 1881558..1881950 (-) 393 WP_001818028.1 competence type IV pilus minor pilin ComGG Machinery gene
  R8474_RS09605 comGF/cglF 1881928..1882389 (-) 462 WP_000250539.1 competence type IV pilus minor pilin ComGF Machinery gene
  R8474_RS09610 (PC0003_18780) comGE/cglE 1882352..1882654 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R8474_RS09615 (PC0003_18790) comGD/cglD 1882617..1883021 (-) 405 WP_000588030.1 competence type IV pilus minor pilin ComGD Machinery gene
  R8474_RS09620 (PC0003_18800) comGC/cglC 1883014..1883340 (-) 327 WP_000738625.1 competence type IV pilus major pilin ComGC Machinery gene
  R8474_RS09625 (PC0003_18810) comGB/cglB 1883342..1884358 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  R8474_RS09630 (PC0003_18820) comGA/cglA/cilD 1884306..1885247 (-) 942 WP_000249549.1 competence type IV pilus ATPase ComGA Machinery gene
  R8474_RS09635 (PC0003_18830) - 1885323..1885688 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35686.85 Da        Isoelectric Point: 4.2706

>NTDB_id=97519 R8474_RS09590 WP_000345127.1 1879794..1880747(-) (comYH) [Streptococcus pneumoniae strain PZ900700003]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSNLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=97519 R8474_RS09590 WP_000345127.1 1879794..1880747(-) (comYH) [Streptococcus pneumoniae strain PZ900700003]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTCGG
CTATTATCCTGATGACGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTAATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAGTGAAATAGCAGTGGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536

Multiple sequence alignment