Detailed information NTG0097500

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: R8474_RS08320
• Genome accession: NZ_AP026914
• Coordinates: 1661576..1662235 (+)
• Length: 219 a.a.
• NCBI ID: WP_000565025.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700003
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1656576..1667235

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8474_RS08280 (PC0003_16490)	mgaSpn	1656838..1658319 (-)	1482	WP_001205281.1	virulence factor transcriptional regulator MgaSpn	-
R8474_RS08285 (PC0003_16500)	-	1658762..1658926 (+)	165	WP_001820780.1	GlsB/YeaQ/YmgE family stress response membrane protein	-
R8474_RS08290	amaP	1659010..1659576 (+)	567	WP_000030213.1	alkaline shock response membrane anchor protein AmaP	-
R8474_RS08295 (PC0003_16520)	-	1659588..1659758 (+)	171	WP_000455066.1	DUF2273 domain-containing protein	-
R8474_RS08300 (PC0003_16530)	-	1659796..1660404 (+)	609	WP_000064115.1	Asp23/Gls24 family envelope stress response protein	-
R8474_RS08305 (PC0003_16540)	-	1660435..1660638 (+)	204	WP_000109957.1	CsbD family protein	-
R8474_RS08310 (PC0003_16550)	-	1660748..1660987 (-)	240	WP_001005784.1	transposase	-
R8474_RS08315 (PC0003_16560)	-	1661060..1661506 (-)	447	WP_000155411.1	GNAT family N-acetyltransferase	-
R8474_RS08320 (PC0003_16570)	cclA/cilC	1661576..1662235 (+)	660	WP_000565025.1	A24 family peptidase	Machinery gene
R8474_RS08325 (PC0003_16580)	-	1662287..1663438 (-)	1152	WP_000481756.1	XRE family transcriptional regulator	-
R8474_RS08330 (PC0003_16590)	-	1663453..1664183 (-)	731	Protein_1652	hypothetical protein	-
R8474_RS08335	-	1664403..1664513 (+)	111	Protein_1653	prepilin peptidase	-
R8474_RS08340 (PC0003_16600)	trpA	1664485..1665261 (-)	777	WP_001127049.1	tryptophan synthase subunit alpha	-
R8474_RS08345 (PC0003_16610)	trpB	1665254..1666477 (-)	1224	WP_000331287.1	tryptophan synthase subunit beta	-
R8474_RS08350 (PC0003_16620)	-	1666455..1667054 (-)	600	WP_000169889.1	phosphoribosylanthranilate isomerase	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24865.96 Da
• Isoelectric Point: 7.6418

>NTDB_id=97500 R8474_RS08320 WP_000565025.1 1661576..1662235(+) (cclA/cilC) [Streptococcus pneumoniae strain PZ900700003]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRYPVWYTLFELVLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=97500 R8474_RS08320 WP_000565025.1 1661576..1662235(+) (cclA/cilC) [Streptococcus pneumoniae strain PZ900700003]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATACCCTCTTTGAATTAGTCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTTGCTCTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGAGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae Rx1	96.804	100	0.968
cclA/cilC	Streptococcus pneumoniae D39	96.804	100	0.968
cclA/cilC	Streptococcus pneumoniae R6	96.804	100	0.968
cclA/cilC	Streptococcus pneumoniae TIGR4	95.89	100	0.959
cclA/cilC	Streptococcus mitis SK321	92.237	100	0.922
cclA/cilC	Streptococcus mitis NCTC 12261	86.758	100	0.868