Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   AAAF57_RS04265 Genome accession   NZ_CP150847
Coordinates   954151..955566 (+) Length   471 a.a.
NCBI ID   WP_013990466.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS5     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 949151..960566
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAAF57_RS04240 (AAAF57_04285) - 949602..950174 (-) 573 WP_022496698.1 ECF transporter S component -
  AAAF57_RS04245 (AAAF57_04290) coaC 950203..950748 (-) 546 WP_022496697.1 phosphopantothenoylcysteine decarboxylase -
  AAAF57_RS04250 (AAAF57_04295) - 950741..951424 (-) 684 WP_022496696.1 phosphopantothenate--cysteine ligase -
  AAAF57_RS04255 (AAAF57_04300) - 951619..953289 (+) 1671 WP_004182072.1 formate--tetrahydrofolate ligase -
  AAAF57_RS04260 (AAAF57_04305) ciaR 953487..954161 (+) 675 WP_002891134.1 response regulator transcription factor Regulator
  AAAF57_RS04265 (AAAF57_04310) ciaH 954151..955566 (+) 1416 WP_013990466.1 sensor histidine kinase Regulator
  AAAF57_RS04270 (AAAF57_04315) rpsT 955644..955880 (-) 237 WP_004182129.1 30S ribosomal protein S20 -
  AAAF57_RS04275 (AAAF57_04320) coaA 955950..956870 (-) 921 WP_004182393.1 type I pantothenate kinase -
  AAAF57_RS04280 (AAAF57_04325) - 956982..957572 (+) 591 WP_410537121.1 class I SAM-dependent methyltransferase -
  AAAF57_RS04285 (AAAF57_04330) - 957569..958846 (+) 1278 WP_410537122.1 pyrimidine-nucleoside phosphorylase -
  AAAF57_RS04290 (AAAF57_04335) deoC 958880..959542 (+) 663 WP_175063727.1 deoxyribose-phosphate aldolase -
  AAAF57_RS04295 (AAAF57_04340) - 959529..959927 (+) 399 WP_410537124.1 cytidine deaminase -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53464.22 Da        Isoelectric Point: 8.7661

>NTDB_id=972963 AAAF57_RS04265 WP_013990466.1 954151..955566(+) (ciaH) [Streptococcus salivarius strain KSS5]
MLTKFFNYLFRRIKSDGFKSFIHFFATFSGIFLIMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDTKGATTETSDSSDSKKEPKKKSKIEDAPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTAQNQVGRPIQTDKTLLKQLMTILFDNAIKYTEDDGHVTFTVRTNDRHLYIS
VADNGPGISDSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVLALKGTIVVKDNQPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=972963 AAAF57_RS04265 WP_013990466.1 954151..955566(+) (ciaH) [Streptococcus salivarius strain KSS5]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATCAAGTCAGACGGATTTAAGTCGTTCATTCATTTCTTTGCCAC
TTTTTCTGGTATTTTCCTTATCATGACTGTCATGATTTTACAGATTCTGAGTTACGGCGTTTATTCCAATGTGGACTCTA
GTCTGAAAATGGCAGCCACTAAGACCAATTCTTATTTAGAAATGGAAATGCTAAAACGGGAACTTTTTCTGACTTCTGAG
GTAGATCAAAATAATACGACGACCATTTACCAGGCTTATGATACTAAAGGGGCGACAACTGAAACATCTGACTCGAGTGA
CTCTAAGAAAGAACCTAAGAAGAAATCAAAAATTGAAGATGCCCCTCACGATTTATCAGTTGCGGCAAATACCAGTGTCT
TAGTGCTTGATAAGAATGGAAAAGTCCTTAATGTTGTTGATAAATTTTCAAGCTTATCCAATTTACCAATAGATAAAAAT
AACATTGATGTTATCAGCAAGGGAAGTGCTCAGAATTATTTCGATCAAACGGAAAAGTATCGTCTGATCACTGAGAAAGT
AGACAATAGCCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCTACTGAACGTT
ATGTTAAGCTCATTGTCATCATGATGAGTTTCTTCTGGCTCTTATCTGTTGCGGCTAGTATGTATTTGGCTAAGTGGTCA
AGACGTCCTATCCAGGAAAGCTTGGAGAAGCAGAAGGCTTTTGTTGAAAATGCTAGTCATGAGTTACGGACACCGCTTGC
TGTGATTCAAAACAGGTTAGAAGTTCTTTTCCGCAAGCCTGAGAGTACTATTTTAGATAATTCAGAGAATATTGCATCAA
GTCTTGATGAAGTACGCAACATGCGTCTTTTGACGACTAATCTTTTGAACTTGGCTCGTCGTGACGATGGTATTAAACCA
GAAATCGAAACCTTAGAACCTGCTTTCTTTGATACAGTCTTTACCAACTATGCCATGATTGCAGAAGAAAATGAGAAAGG
TTTCACGGCTCAAAACCAAGTTGGTCGTCCAATCCAGACTGATAAAACGTTATTGAAACAGTTAATGACCATCTTATTTG
ATAATGCGATTAAATATACGGAAGATGACGGACATGTTACCTTTACTGTCCGCACTAATGACCGGCATCTTTATATTTCT
GTAGCTGATAATGGTCCTGGAATATCAGATAGTGATAAGAAAAAAATCTTTGATCGATTTTATCGCGTAGATAAGGCTAG
AACCAGACAAAAAGGTGGGTTTGGACTTGGCTTATCCCTAGCGCAACAAATTGTTTTAGCCCTTAAAGGAACAATTGTTG
TTAAAGATAATCAACCAAAGGGAACGATTTTTGAAGTTAAGATCACCGGAGTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.522

97.665

0.552
  ciaH Streptococcus pneumoniae Rx1

50.431

98.514

0.497
  ciaH Streptococcus pneumoniae D39

50.431

98.514

0.497
  ciaH Streptococcus pneumoniae R6

50.431

98.514

0.497
  ciaH Streptococcus pneumoniae TIGR4

50.431

98.514

0.497

Multiple sequence alignment