Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   ACJWMD_RS07915 Genome accession   NZ_CP177182
Coordinates   1679771..1682011 (-) Length   746 a.a.
NCBI ID   WP_004183180.1    Uniprot ID   -
Organism   Streptococcus salivarius strain MRD6060     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1674771..1687011
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMD_RS07895 - 1675639..1676499 (-) 861 WP_004183173.1 methionyl aminopeptidase -
  ACJWMD_RS07900 spxR 1676539..1677819 (-) 1281 WP_004183175.1 CBS-HotDog domain-containing transcription factor SpxR -
  ACJWMD_RS07905 - 1677812..1678357 (-) 546 WP_004183177.1 GNAT family N-acetyltransferase -
  ACJWMD_RS07910 - 1678423..1679685 (-) 1263 WP_004183178.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  ACJWMD_RS07915 comEC/celB 1679771..1682011 (-) 2241 WP_004183180.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ACJWMD_RS07920 comEA 1682001..1682696 (-) 696 WP_004183181.1 helix-hairpin-helix domain-containing protein Machinery gene
  ACJWMD_RS07925 - 1682805..1683560 (-) 756 WP_004183182.1 lysophospholipid acyltransferase family protein -
  ACJWMD_RS07930 - 1683690..1684625 (+) 936 WP_037605714.1 polysaccharide deacetylase family protein -
  ACJWMD_RS07935 - 1684675..1685439 (+) 765 WP_004183185.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  ACJWMD_RS07940 - 1685443..1685712 (+) 270 WP_004183187.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 746 a.a.        Molecular weight: 84671.69 Da        Isoelectric Point: 10.0248

>NTDB_id=969858 ACJWMD_RS07915 WP_004183180.1 1679771..1682011(-) (comEC/celB) [Streptococcus salivarius strain MRD6060]
MWLKKAPINLFSLALLIAALYFMIFVTNVYAMGAFAFLLVCFLKHHWKNKAALKLVGLVGGFFLIYFLFLHHRASIQDKQ
APAEINQVSLVADTLSVNGEQLSAIGKAKGQTYQVFYRLKSEKEQHFFKTTSQTLVLKGKIKLSPATGQRNFQGFNYKSY
LASQGIYRMAQIERLDHVVPQKNTSPLAFFHQLRRRALVHIQTHFPNPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKDYLFIILLPFSLCYGLMTGWTASVLRSLIQSLLTEFGIKKLDNMGITLLLLFLF
LPHFLLTVGGVLSCSYAFLLCLFDFEEMSSLKKSICTSLVLSLGILPFLTYYYGTFQPVSLILTAMFSIVFDSFLLPVLT
VFFVLSGLVIFSQINLLFEWMETFLTWIQSWIGQPLILGKPSLFQFGLMIAVLVMLFDFWKKPQFRICLLMIFSLLMVWV
KHPLTNEVTMVDVGQGDSIFLRSMRGDTILIDVGGKVTFGSKEKWQEASQTSNAEKTLIPYLQARGVSQIDHLVLTHTDT
DHIGDLEEVAKRFKIKEVCVSQGALTKPSFVKRLRTLKRPVRTLKAGDKLPMMGSKLQVLYPNKVGDGGNNDSIVLYGKL
LGSSFLFTGDLEKEGEEELIASYPNLKASILKAGHHGSKGSSSEAFLDQLQPSLALVSAGENNRYKHPNDETLKRFKKRH
IKVLRTDQNGAIRFKEWFKWSSETVR

Nucleotide


Download         Length: 2241 bp        

>NTDB_id=969858 ACJWMD_RS07915 WP_004183180.1 1679771..1682011(-) (comEC/celB) [Streptococcus salivarius strain MRD6060]
ATGTGGCTTAAAAAAGCTCCAATCAATCTTTTTTCCTTGGCTCTGTTAATAGCTGCTCTTTATTTTATGATTTTTGTCAC
TAATGTTTATGCTATGGGGGCTTTTGCTTTTCTTTTAGTATGTTTTTTGAAGCATCATTGGAAGAATAAGGCAGCCCTAA
AGTTGGTGGGGCTTGTAGGTGGGTTCTTTTTGATTTATTTTTTATTCTTGCATCACAGAGCTAGCATACAAGATAAACAA
GCTCCTGCTGAAATCAATCAGGTGAGTCTGGTTGCTGATACGCTGTCGGTTAATGGTGAGCAATTATCAGCTATTGGAAA
GGCAAAGGGACAAACCTATCAGGTCTTTTACCGACTCAAATCTGAGAAGGAGCAGCATTTTTTTAAGACTACTAGCCAAA
CGCTAGTATTAAAAGGGAAAATAAAGTTATCCCCAGCAACTGGTCAACGTAATTTTCAAGGGTTTAATTATAAGTCTTAT
CTAGCCAGTCAAGGTATTTATCGAATGGCTCAGATTGAGCGCTTGGACCATGTGGTGCCTCAAAAAAACACATCTCCCCT
AGCTTTTTTCCACCAACTGAGGAGGAGGGCTTTGGTTCATATCCAGACGCACTTTCCTAATCCTATGAGACACTATATGA
CAGGCCTGCTCTTTGGGTATTTGGATAAGGAGTTTGATGAGCAAAGTCAGCTTTACACAAGCTTAGGTATTATTCATCTA
TTCGCACTTTCAGGGATGCAAGTGGGCTTTTTTCTGGGATGGTTTCGCTACGGACTCCTACGCTTGGGCCTTCCTAAAGA
TTATCTATTTATTATCTTGCTGCCTTTTTCCTTATGCTATGGCTTAATGACAGGTTGGACAGCTTCAGTCCTACGTTCCT
TGATTCAAAGTTTGTTGACGGAGTTTGGTATTAAAAAACTGGATAATATGGGTATAACCTTGCTTTTATTGTTTCTCTTT
TTACCTCATTTTCTTTTGACAGTGGGAGGTGTTTTAAGTTGTTCCTATGCCTTCTTGTTGTGTTTGTTTGATTTTGAGGA
GATGTCATCTCTTAAAAAGTCAATCTGTACGAGCTTGGTATTGAGTCTTGGGATTTTGCCCTTTCTAACTTACTATTATG
GGACCTTTCAACCGGTGAGTTTAATTCTGACGGCGATGTTTTCGATAGTCTTTGATAGCTTTCTCTTACCTGTCTTGACG
GTCTTCTTTGTCCTTTCAGGACTAGTAATCTTTTCTCAAATCAACCTACTTTTTGAATGGATGGAGACCTTTTTGACTTG
GATACAATCCTGGATAGGCCAGCCTTTGATTTTAGGGAAACCTAGTTTGTTTCAGTTTGGCTTGATGATAGCTGTATTGG
TTATGCTCTTTGATTTTTGGAAAAAGCCCCAGTTTAGGATTTGTCTTTTGATGATTTTTAGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAACCAATGAGGTGACCATGGTTGACGTTGGTCAGGGAGATAGTATTTTTCTGAGAAGTATGAGAGGCGA
TACCATCTTAATTGATGTGGGTGGCAAGGTGACTTTTGGTTCAAAGGAAAAATGGCAAGAGGCTAGTCAGACGAGCAATG
CGGAGAAAACCTTGATTCCCTATCTACAGGCTAGGGGAGTGTCTCAAATTGATCATCTGGTCCTGACTCATACGGACACA
GACCATATTGGTGATTTGGAAGAAGTAGCCAAGCGGTTTAAGATTAAGGAAGTCTGTGTCAGTCAAGGAGCTTTGACTAA
GCCTAGTTTTGTGAAACGACTTCGGACTTTAAAACGCCCAGTTCGCACTCTAAAAGCTGGTGATAAACTGCCTATGATGG
GAAGTAAGCTACAGGTTCTTTATCCAAATAAAGTTGGTGATGGTGGTAATAATGATTCGATAGTGCTCTATGGAAAATTA
TTAGGAAGCAGTTTTCTGTTTACTGGTGATTTGGAAAAAGAAGGTGAGGAGGAACTGATAGCCAGTTATCCCAATTTAAA
GGCAAGTATCCTCAAAGCCGGACACCACGGTTCAAAAGGGTCATCGTCTGAAGCGTTTTTGGACCAGTTGCAGCCCTCCC
TTGCCCTTGTTTCAGCCGGTGAGAACAATCGTTATAAACATCCAAATGATGAAACTTTGAAGCGTTTTAAGAAACGTCAC
ATTAAGGTTTTACGAACAGACCAGAACGGTGCTATCCGTTTTAAGGAGTGGTTTAAGTGGTCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterProScan.

Competence protein (Competence)

(216-462)

Metallo-beta-lactamase superfamily (Lactamase_B)

(492-699)

Domain of unknown function (DUF4131) (DUF4131)

(30-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis NCTC 12261

47.587

100

0.476
  comEC/celB Streptococcus mitis SK321

47.256

100

0.473
  comEC/celB Streptococcus pneumoniae Rx1

46.452

100

0.465
  comEC/celB Streptococcus pneumoniae D39

46.452

100

0.465
  comEC/celB Streptococcus pneumoniae R6

46.452

100

0.465
  comEC/celB Streptococcus pneumoniae TIGR4

46.319

100

0.464
  comEC Lactococcus lactis subsp. cremoris KW2

43.378

99.196

0.43