Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   ACJWMD_RS02315 Genome accession   NZ_CP177182
Coordinates   440183..441010 (-) Length   275 a.a.
NCBI ID   WP_224119046.1    Uniprot ID   -
Organism   Streptococcus salivarius strain MRD6060     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 435183..446010
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMD_RS02285 - 435269..436030 (+) 762 WP_002886742.1 IS110 family transposase -
  ACJWMD_RS02290 - 436050..436436 (+) 387 WP_002886743.1 IS110 family transposase -
  ACJWMD_RS02295 - 436501..437037 (+) 537 WP_002886744.1 hypothetical protein -
  ACJWMD_RS02300 - 437130..437822 (+) 693 WP_002886745.1 hypothetical protein -
  ACJWMD_RS02305 - 438141..438800 (+) 660 WP_002886746.1 ABC transporter ATP-binding protein -
  ACJWMD_RS02310 - 438815..439531 (+) 717 WP_002886747.1 hypothetical protein -
  ACJWMD_RS02315 comD/blpH 440183..441010 (-) 828 WP_224119046.1 sensor histidine kinase Regulator
  ACJWMD_RS02320 comE/blpR 441500..442243 (-) 744 WP_002886749.1 response regulator transcription factor Regulator
  ACJWMD_RS02325 tnpA 443768..444184 (+) 417 WP_002886752.1 IS200/IS605 family transposase -
  ACJWMD_RS02330 - 444502..444888 (+) 387 WP_002886754.1 helix-turn-helix domain-containing protein -
  ACJWMD_RS02335 - 445023..445715 (+) 693 WP_002886755.1 DUF6287 domain-containing protein -

Sequence

Protein


Download         Length: 275 a.a.        Molecular weight: 31503.35 Da        Isoelectric Point: 6.7586

>NTDB_id=969807 ACJWMD_RS02315 WP_224119046.1 440183..441010(-) (comD/blpH) [Streptococcus salivarius strain MRD6060]
MLVYMLLVSTFVIYRDKLANADIWRGHINNFYIILFFVMLLYLNAISKEKLEKEIIKQKDTQLYELSSYSHHVESLYEEI
RGFRHDYINILTSLKLGIDNQDIDAVKTVYNDVLRDSAKQFYDSKFDIAKLSNIKNDAIKSILSAKLLEAQNRGISISVE
VEEPISNFRIELLDFITVLSVLCDNAIEAAIETISPKMTVVFINNDDSLVLIVENSIKSEKVEVSRIFVRGHSSKGEGRG
IGLYNVNSILEKYPKSTITTRSANHLFSQTIRFCK

Nucleotide


Download         Length: 828 bp        

>NTDB_id=969807 ACJWMD_RS02315 WP_224119046.1 440183..441010(-) (comD/blpH) [Streptococcus salivarius strain MRD6060]
ATGCTTGTATATATGTTGTTAGTTTCTACATTTGTTATTTATAGAGATAAATTAGCTAATGCAGACATCTGGAGAGGGCA
TATTAACAACTTTTATATTATTCTGTTTTTTGTAATGCTACTCTACCTCAATGCAATCTCAAAAGAAAAACTAGAGAAGG
AAATAATTAAGCAAAAGGACACCCAATTATATGAACTATCTAGTTACAGCCATCACGTTGAATCCCTTTATGAGGAAATT
AGAGGTTTCCGTCATGACTACATTAATATTTTGACAAGTCTAAAATTAGGGATTGATAATCAAGATATTGACGCTGTTAA
AACTGTTTACAATGATGTCCTTAGAGACAGTGCAAAACAATTCTATGATAGTAAGTTTGATATAGCTAAGCTTAGCAATA
TTAAGAATGATGCTATTAAAAGTATTCTTTCCGCTAAATTACTCGAGGCACAGAATAGAGGGATTTCAATTTCTGTCGAG
GTTGAAGAACCTATTAGCAATTTTAGGATAGAATTACTAGATTTTATCACTGTTCTATCTGTCCTTTGTGACAATGCTAT
CGAAGCCGCCATTGAAACTATTAGTCCGAAAATGACTGTCGTTTTCATAAATAATGATGATTCGTTGGTGCTTATCGTCG
AAAATAGTATAAAATCAGAAAAGGTCGAGGTTAGTCGCATTTTTGTTAGAGGTCACTCTAGTAAAGGGGAGGGTAGAGGT
ATTGGCTTATATAATGTAAATAGTATATTGGAAAAATACCCTAAATCTACGATTACCACTCGTAGTGCAAATCACCTCTT
TTCTCAAACTATCAGATTTTGTAAATAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(172-271)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

45.556

98.182

0.447
  comD/comD1 Streptococcus equinus JB1

49.565

83.636

0.415
  comD/comD2 Streptococcus equinus JB1

40.293

99.273

0.4
  comD/comD3 Streptococcus equinus JB1

42.688

92

0.393