Detailed information NTG0968338

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: MKX38_RS18090
• Genome accession: NZ_CP150258
• Coordinates: 3493974..3495131 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus sp. FSL M8-0025
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3488974..3500131

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MKX38_RS18060 (MKX38_18060)	-	3489227..3489646 (-)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-
MKX38_RS18065 (MKX38_18065)	comFC	3489720..3490442 (-)	723	WP_003227991.1	comF operon protein ComFC	Machinery gene
MKX38_RS18070 (MKX38_18070)	comFB	3490406..3490702 (-)	297	WP_003227989.1	late competence protein ComFB	-
MKX38_RS18075 (MKX38_18075)	comFA	3490762..3492153 (-)	1392	WP_339187936.1	ATP-dependent helicase ComFA	Machinery gene
MKX38_RS18080 (MKX38_18080)	-	3492259..3493104 (-)	846	WP_003244125.1	DegV family protein	-
MKX38_RS18085 (MKX38_18085)	degU	3493202..3493891 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
MKX38_RS18090 (MKX38_18090)	degS	3493974..3495131 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
MKX38_RS18095 (MKX38_18095)	-	3495348..3496001 (+)	654	WP_003227979.1	YigZ family protein	-
MKX38_RS18100 (MKX38_18100)	tagV	3496001..3497176 (+)	1176	WP_339187939.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
MKX38_RS18105 (MKX38_18105)	-	3497249..3498325 (-)	1077	WP_339187943.1	MraY family glycosyltransferase	-
MKX38_RS18110 (MKX38_18110)	-	3498470..3499663 (-)	1194	WP_339189466.1	glycosyltransferase family 1 protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=968338 MKX38_RS18090 WP_003227983.1 3493974..3495131(-) (degS) [Bacillus sp. FSL M8-0025]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=968338 MKX38_RS18090 WP_003227983.1 3493974..3495131(-) (degS) [Bacillus sp. FSL M8-0025]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAAGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTTGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATTGAGCTTGGCGATAAACTTGAAGTGCAAACTCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATCATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTACGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1