Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   NYE32_RS05785 Genome accession   NZ_CP150201
Coordinates   1200275..1201690 (-) Length   471 a.a.
NCBI ID   WP_073689923.1    Uniprot ID   -
Organism   Streptococcus sp. FSL R7-0248     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1195275..1206690
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYE32_RS05755 (NYE32_05755) - 1195906..1196304 (-) 399 WP_156685121.1 cytidine deaminase -
  NYE32_RS05760 (NYE32_05760) deoC 1196291..1196953 (-) 663 WP_156685122.1 deoxyribose-phosphate aldolase -
  NYE32_RS05765 (NYE32_05765) - 1196987..1198264 (-) 1278 WP_156685123.1 pyrimidine-nucleoside phosphorylase -
  NYE32_RS05770 (NYE32_05770) - 1198261..1198851 (-) 591 WP_110981457.1 class I SAM-dependent methyltransferase -
  NYE32_RS05775 (NYE32_05775) coaA 1198964..1199884 (+) 921 WP_037597889.1 type I pantothenate kinase -
  NYE32_RS05780 (NYE32_05780) rpsT 1199954..1200190 (+) 237 WP_037597891.1 30S ribosomal protein S20 -
  NYE32_RS05785 (NYE32_05785) ciaH 1200275..1201690 (-) 1416 WP_073689923.1 HAMP domain-containing sensor histidine kinase Regulator
  NYE32_RS05790 (NYE32_05790) ciaR 1201680..1202354 (-) 675 WP_049546057.1 response regulator transcription factor Regulator
  NYE32_RS05795 (NYE32_05795) - 1202553..1204223 (-) 1671 WP_004182072.1 formate--tetrahydrofolate ligase -
  NYE32_RS05800 (NYE32_05800) - 1204418..1205101 (+) 684 WP_073689924.1 phosphopantothenate--cysteine ligase -
  NYE32_RS05805 (NYE32_05805) coaC 1205094..1205639 (+) 546 WP_004182390.1 phosphopantothenoylcysteine decarboxylase -
  NYE32_RS05810 (NYE32_05810) - 1205668..1206240 (+) 573 WP_004182389.1 ECF transporter S component -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53539.35 Da        Isoelectric Point: 9.0385

>NTDB_id=966171 NYE32_RS05785 WP_073689923.1 1200275..1201690(-) (ciaH) [Streptococcus sp. FSL R7-0248]
MLTKFFNYLFRRIKSEGFKSFIHFFATFSGIFLVMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDTKGSTDETPDSSGSKKESKKKSKMEDAPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTAQNQVSRPIQTDKTLLKQLMTILFDNAIKYTEDDGHVIFSVRTNDRHLYIS
VADNGPGISYSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVLALKGTIVVKDNHPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=966171 NYE32_RS05785 WP_073689923.1 1200275..1201690(-) (ciaH) [Streptococcus sp. FSL R7-0248]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATCAAGTCAGAAGGATTTAAGTCTTTCATTCATTTCTTTGCCAC
TTTTTCTGGTATTTTCCTTGTCATGACTGTCATGATTTTGCAGATTCTGAGTTACGGCGTTTATTCAAATGTGGATTCTA
GTCTGAAAATGGCAGCAACTAAGACCAATTCTTATTTAGAAATGGAAATGCTAAAACGGGAACTTTTTCTGACTTCTGAG
GTAGATCAAAATAATACGACAACCATCTACCAAGCCTATGATACTAAAGGGTCGACAGATGAAACACCTGACTCGAGTGG
CTCTAAAAAAGAATCTAAAAAGAAATCAAAGATGGAAGATGCCCCTCACGATTTATCTGTTGCGGCGAATACCAGTGTCT
TAGTGCTTGATAAGAATGGAAAAGTCCTCAATGTCGTTGATAAATTTTCTAGCTTATCCAATTTACCAATAGATAAAAAT
AACATTGATGTTATCAGCAAGGGAAGCGCTCAGAATTATTTCGATCAAACCGAAAAGTATCGCCTGATTACTGAAAAAGT
AGATAATAGTCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCCACTGAACGTT
ATGTCAAGCTCATTGTCATCATGATGAGTTTCTTCTGGCTCCTATCTGTTGCGGCTAGTATGTATTTGGCCAAGTGGTCA
AGACGTCCTATCCAGGAAAGTCTGGAGAAGCAGAAGGCATTTGTTGAAAATGCCAGTCACGAGTTACGGACACCGCTTGC
TGTGATTCAAAACCGATTAGAAGTTCTTTTCCGCAAGCCTGAGAGCACCATTTTAGATAATTCAGAGAATATTGCTTCAA
GTCTTGATGAAGTACGTAATATGCGTCTGTTGACGACAAATCTCTTGAACTTGGCTCGTCGTGACGATGGTATTAAGCCG
GAAATCGAAACCTTAGAACCTGCTTTCTTTGATACAGTATTTACCAATTATGCCATGATTGCTGAAGAAAACGAGAAAGG
ATTTACGGCCCAAAACCAAGTTAGCCGTCCTATTCAGACTGATAAAACGCTACTGAAGCAGCTAATGACGATTTTATTTG
ATAATGCTATTAAGTATACAGAAGATGATGGACATGTTATCTTTTCGGTTCGCACTAATGACCGACATCTTTATATTTCG
GTAGCTGATAATGGTCCTGGTATATCATATAGTGATAAGAAAAAAATCTTTGATCGCTTTTATCGCGTAGATAAGGCTAG
AACCAGACAAAAAGGTGGGTTTGGACTGGGCTTATCCCTAGCGCAACAAATTGTTTTAGCTCTTAAAGGAACAATTGTTG
TCAAGGACAATCATCCGAAGGGGACTATTTTTGAAGTTAAAATCACTGGAGTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.087

97.665

0.548
  ciaH Streptococcus pneumoniae Rx1

50

98.514

0.493
  ciaH Streptococcus pneumoniae D39

50

98.514

0.493
  ciaH Streptococcus pneumoniae R6

50

98.514

0.493
  ciaH Streptococcus pneumoniae TIGR4

50

98.514

0.493

Multiple sequence alignment