Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   NSQ79_RS04175 Genome accession   NZ_CP150200
Coordinates   960460..961875 (+) Length   471 a.a.
NCBI ID   WP_049527921.1    Uniprot ID   A0A6G4N955
Organism   Streptococcus sp. FSL W7-1342     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 955460..966875
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NSQ79_RS04150 (NSQ79_04150) - 955910..956482 (-) 573 WP_004182105.1 ECF transporter S component -
  NSQ79_RS04155 (NSQ79_04155) coaC 956511..957056 (-) 546 WP_073687142.1 phosphopantothenoylcysteine decarboxylase -
  NSQ79_RS04160 (NSQ79_04160) - 957049..957732 (-) 684 WP_073687143.1 phosphopantothenate--cysteine ligase -
  NSQ79_RS04165 (NSQ79_04165) - 957927..959597 (+) 1671 WP_073687144.1 formate--tetrahydrofolate ligase -
  NSQ79_RS04170 (NSQ79_04170) ciaR 959796..960470 (+) 675 WP_002891134.1 response regulator transcription factor Regulator
  NSQ79_RS04175 (NSQ79_04175) ciaH 960460..961875 (+) 1416 WP_049527921.1 HAMP domain-containing sensor histidine kinase Regulator
  NSQ79_RS04180 (NSQ79_04180) rpsT 961959..962195 (-) 237 WP_004182129.1 30S ribosomal protein S20 -
  NSQ79_RS04185 (NSQ79_04185) coaA 962265..963185 (-) 921 WP_004182393.1 type I pantothenate kinase -
  NSQ79_RS04190 (NSQ79_04190) - 963298..963888 (+) 591 WP_004182394.1 class I SAM-dependent methyltransferase -
  NSQ79_RS04195 (NSQ79_04195) - 963885..965162 (+) 1278 WP_004182395.1 pyrimidine-nucleoside phosphorylase -
  NSQ79_RS04200 (NSQ79_04200) deoC 965196..965858 (+) 663 WP_004182396.1 deoxyribose-phosphate aldolase -
  NSQ79_RS04205 (NSQ79_04205) - 965845..966243 (+) 399 WP_049527913.1 cytidine deaminase -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53525.30 Da        Isoelectric Point: 8.7640

>NTDB_id=966100 NSQ79_RS04175 WP_049527921.1 960460..961875(+) (ciaH) [Streptococcus sp. FSL W7-1342]
MLTKFFNYLFRRIKSDGFKSFIHFFATFSGIFLIMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDTKESTAETPDSSGSKKEPKKKSKIEDTPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTAQNQVSRPIQTDKTLLKQLMTILFDNAIKYTEDDGHVTFTVRTNDRQLYIS
VADNGPGISDSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVLALKGTIVVKDNQPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=966100 NSQ79_RS04175 WP_049527921.1 960460..961875(+) (ciaH) [Streptococcus sp. FSL W7-1342]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATCAAGTCAGACGGATTTAAGTCGTTCATTCATTTCTTTGCTAC
TTTTTCTGGTATTTTCCTTATCATGACTGTCATGATTTTGCAGATTCTGAGTTACGGTGTCTATTCCAATGTGGACTCTA
GTCTGAAAATGGCAGCCACTAAGACCAATTCTTATTTAGAAATGGAAATGCTCAAACGGGAACTTTTTCTGACTTCTGAG
GTGGATCAAAATAATACGACAACCATTTACCAAGCCTATGATACTAAAGAGTCGACAGCTGAAACACCTGACTCGAGTGG
CTCTAAAAAAGAACCTAAGAAGAAATCAAAAATTGAAGATACCCCTCACGATTTATCTGTTGCGGCAAATACTAGTGTCT
TGGTACTTGATAAGAATGGAAAAGTCCTTAATGTCGTTGATAAATTTTCAAGCTTATCCAATTTACCAATAGACAAAAAT
AACATTGATGTTATCAGCAAGGGAAGTGCTCAGAATTATTTCGATCAAACGGAAAAGTACCGTCTGATTACTGAAAAAGT
AGATAATAGCCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCCACTGAACGTT
ATGTTAAGCTAATTGTCATCATGATGAGTTTCTTCTGGCTTTTATCTGTTGCGGCTAGTATGTATTTGGCTAAGTGGTCA
AGACGTCCTATCCAGGAAAGCTTGGAGAAGCAGAAGGCTTTTGTTGAGAATGCTAGCCATGAGTTACGGACACCGCTTGC
TGTGATTCAAAACAGATTAGAAGTTCTTTTCCGCAAGCCTGAGAGCACCATTCTAGATAATTCAGAGAATATTGCTTCAA
GTCTTGATGAAGTACGCAACATGCGTCTTTTGACGACTAATCTTTTGAACTTGGCTCGTCGTGACGATGGTATTAAACCA
GAAATCGAAACCTTAGAACCTGCTTTCTTTGATACAGTATTTACCAACTATGCCATGATTGCAGAAGAAAATGAGAAAGG
TTTCACGGCTCAAAATCAAGTTAGTCGTCCAATCCAAACTGATAAAACGCTATTGAAACAGTTAATGACCATCTTATTTG
ATAATGCTATTAAATATACGGAAGATGATGGACATGTTACCTTTACTGTTCGCACTAATGACCGCCAACTTTATATTTCT
GTAGCTGATAATGGTCCTGGGATATCAGATAGTGATAAGAAAAAAATCTTTGATCGATTTTATCGCGTAGATAAGGCTAG
AACCAGACAAAAAGGTGGGTTTGGACTTGGCTTATCCCTAGCGCAACAAATTGTTTTAGCCCTAAAAGGAACAATTGTTG
TTAAAGATAATCAACCAAAGGGAACGATTTTTGAAGTTAAGATCACTGGAGTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G4N955

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.739

97.665

0.554
  ciaH Streptococcus pneumoniae Rx1

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae D39

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae R6

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae TIGR4

50.216

98.514

0.495

Multiple sequence alignment