Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   NYE79_RS06190 Genome accession   NZ_CP150168
Coordinates   1222268..1223605 (-) Length   445 a.a.
NCBI ID   WP_070800372.1    Uniprot ID   -
Organism   Streptococcus sp. FSL W8-0197     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1217268..1228605
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYE79_RS06165 (NYE79_06165) rpiA 1217941..1218624 (-) 684 WP_339293618.1 ribose-5-phosphate isomerase RpiA -
  NYE79_RS06170 (NYE79_06170) - 1218730..1219659 (-) 930 WP_198464745.1 peptidase U32 family protein -
  NYE79_RS06175 (NYE79_06175) - 1219785..1220465 (-) 681 WP_000125730.1 ABC transporter ATP-binding protein -
  NYE79_RS06180 (NYE79_06180) - 1220479..1221534 (-) 1056 WP_000280277.1 ABC transporter permease -
  NYE79_RS06185 (NYE79_06185) - 1221919..1222203 (+) 285 WP_001276159.1 DUF3270 domain-containing protein -
  NYE79_RS06190 (NYE79_06190) ciaH 1222268..1223605 (-) 1338 WP_070800372.1 HAMP domain-containing sensor histidine kinase Regulator
  NYE79_RS06195 (NYE79_06195) ciaR 1223595..1224269 (-) 675 WP_000590630.1 two-component system response regulator CiaR Regulator
  NYE79_RS06200 (NYE79_06200) - 1224376..1226922 (-) 2547 WP_001149146.1 M1 family metallopeptidase -
  NYE79_RS06205 (NYE79_06205) - 1227043..1227483 (-) 441 WP_049518538.1 ASCH domain-containing protein -
  NYE79_RS06210 (NYE79_06210) - 1227480..1228328 (-) 849 WP_049518537.1 putative PEP-binding protein -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 50803.47 Da        Isoelectric Point: 9.4710

>NTDB_id=964614 NYE79_RS06190 WP_070800372.1 1222268..1223605(-) (ciaH) [Streptococcus sp. FSL W8-0197]
MFNKLKKTWYADDFSYFIRNFGVFTLIFSAMTLIILQVMHSSLYTSVDEKLQALSSSPQAVIQLALNRATEEVKDIQPAT
ADANKAEIKPNVSSNTEVLLFDKDFNQLLLGNRFLGLDKIKLDKKELNHIRQIQVVNSYGQEETYRMILMETNSSSVSSN
VKYAAVLINTSQLEQISQNHEHLIVVVMASFWLLSLIASVYLARVSVKPLLESMQKQKSFVENASHELRTPLAVLQNRLE
NLFRKPEATIMESSESIASSLEEVRNMRFLTTNLLNLARRDDGIKPEIAEVSPQFFKTTFANYELIASENDRIFEYENQI
YRPFMTDQLLLKQLMTILFDNAIKYTEEDGKIEFIVHATDRHLYLTVTDNGIGISAADKKKIFDRFYRVDKARTRQKGGF
GLGLSLAKQIVDALRGTISVKDNKPRGTIFEVKIAIQSPSKRKNK

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=964614 NYE79_RS06190 WP_070800372.1 1222268..1223605(-) (ciaH) [Streptococcus sp. FSL W8-0197]
ATGTTCAATAAACTAAAAAAAACATGGTATGCGGATGATTTCAGCTATTTCATTCGAAACTTTGGAGTGTTCACCCTGAT
CTTCTCTGCTATGACCTTGATTATCCTCCAGGTCATGCACTCGAGTCTCTACACTTCTGTAGATGAAAAACTCCAAGCCC
TTAGTAGCAGTCCCCAAGCGGTTATCCAGTTAGCCCTGAATCGGGCAACTGAAGAGGTTAAGGATATTCAACCAGCAACA
GCGGATGCCAACAAGGCTGAAATCAAGCCCAATGTCAGCTCCAATACGGAAGTCTTGCTCTTTGACAAGGATTTTAATCA
GCTCTTACTGGGCAATCGCTTTTTAGGTTTGGACAAGATCAAGCTGGACAAAAAGGAGTTGAATCACATTCGCCAAATCC
AAGTTGTCAATAGCTATGGTCAGGAAGAAACCTATCGGATGATTTTGATGGAAACCAACTCATCTTCCGTCTCAAGTAAC
GTCAAATATGCTGCGGTTTTAATCAATACCAGCCAGCTCGAGCAAATCAGCCAAAACCACGAGCATTTAATTGTTGTAGT
CATGGCTAGTTTCTGGCTCCTGTCTTTAATTGCCAGTGTTTATCTGGCACGTGTCAGTGTCAAACCCTTGCTGGAAAGTA
TGCAAAAGCAGAAGTCCTTTGTTGAAAATGCGAGTCACGAACTGAGAACGCCTTTGGCCGTTTTACAAAATCGTTTAGAA
AATCTCTTTCGAAAACCAGAGGCAACGATTATGGAATCCAGCGAAAGTATCGCTTCCAGTCTTGAAGAAGTTCGCAACAT
GCGCTTCCTCACGACCAATCTTCTCAACCTTGCACGTCGCGATGATGGAATTAAACCAGAAATAGCAGAAGTATCACCAC
AGTTCTTTAAGACGACCTTTGCTAACTATGAGTTGATTGCTTCTGAAAATGATCGTATTTTTGAGTATGAAAATCAGATT
TATCGTCCCTTTATGACCGATCAGTTGCTCCTAAAACAGCTCATGACCATCTTATTTGACAATGCCATCAAGTATACTGA
AGAAGATGGGAAAATTGAGTTTATAGTCCATGCTACAGATCGTCACCTCTATCTAACAGTAACGGATAACGGAATTGGAA
TCTCAGCTGCTGACAAGAAGAAAATCTTTGACCGTTTTTATCGTGTAGACAAGGCAAGAACTCGTCAGAAAGGTGGCTTT
GGTCTTGGACTATCCTTGGCCAAGCAAATCGTAGATGCCTTACGAGGAACGATTAGCGTAAAAGATAACAAACCTAGAGG
AACAATTTTTGAAGTTAAGATCGCTATTCAATCTCCTTCAAAACGTAAGAATAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(218-283)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(327-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

83.747

99.551

0.834
  ciaH Streptococcus pneumoniae D39

83.747

99.551

0.834
  ciaH Streptococcus pneumoniae R6

83.747

99.551

0.834
  ciaH Streptococcus pneumoniae TIGR4

83.747

99.551

0.834
  ciaH Streptococcus mutans UA159

54.795

98.427

0.539

Multiple sequence alignment