Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   NYE79_RS02235 Genome accession   NZ_CP150168
Coordinates   435866..436603 (+) Length   245 a.a.
NCBI ID   WP_101800372.1    Uniprot ID   -
Organism   Streptococcus sp. FSL W8-0197     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 430866..441603
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYE79_RS02200 (NYE79_02200) - 431594..432247 (-) 654 WP_185758138.1 hypothetical protein -
  NYE79_RS02205 (NYE79_02205) - 432314..432592 (-) 279 WP_125384973.1 hypothetical protein -
  NYE79_RS02210 (NYE79_02210) - 432602..433012 (-) 411 WP_125384974.1 HIT family protein -
  NYE79_RS02215 (NYE79_02215) pptA 433080..433811 (+) 732 WP_101800368.1 ABC transporter ATP-binding protein Regulator
  NYE79_RS02220 (NYE79_02220) - 433808..434857 (+) 1050 WP_101800369.1 ABC transporter permease -
  NYE79_RS02225 (NYE79_02225) - 434915..435244 (-) 330 WP_101800370.1 helicase BlpT -
  NYE79_RS02230 (NYE79_02230) - 435523..435861 (+) 339 WP_101800371.1 LytTR family DNA-binding domain-containing protein -
  NYE79_RS02235 (NYE79_02235) comE/blpR 435866..436603 (+) 738 WP_101800372.1 LytTR family DNA-binding domain-containing protein Regulator
  NYE79_RS02240 (NYE79_02240) - 436617..437957 (+) 1341 WP_095726453.1 sensor histidine kinase -
  NYE79_RS02245 (NYE79_02245) blpC 438000..438155 (-) 156 WP_000360258.1 quorum-sensing system pheromone BlpC -
  NYE79_RS02250 (NYE79_02250) - 438212..439573 (-) 1362 WP_095726454.1 bacteriocin secretion accessory protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28721.86 Da        Isoelectric Point: 6.0460

>NTDB_id=964597 NYE79_RS02235 WP_101800372.1 435866..436603(+) (comE/blpR) [Streptococcus sp. FSL W8-0197]
MRIFVLEDDFSQQARIETVIEKLLKEHHITPSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYADSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSPRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFANGGSCLIARYKVREVSEA
INNLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=964597 NYE79_RS02235 WP_101800372.1 435866..436603(+) (comE/blpR) [Streptococcus sp. FSL W8-0197]
ATGAGAATATTTGTTTTAGAAGATGATTTTTCCCAACAAGCTAGGATTGAAACGGTGATTGAGAAACTCTTGAAGGAACA
TCATATCACTCCGAGTTCTTTTGAAGTTTTTGGCAAGCCAGACCAACTGCTAGCAGAGGTGCATGAGAAGGGAGCACATC
AGCTTTTCTTTTTGGACATTGAGATTCGAAATGAGGAGATGAAAGGCCTAGAAGTGGCAAGAAAGATTCGGGATCGAGAT
CCTTATGCCCTGATTGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTGTCCTTTCGCTACCAGGTATCAGCTTTGGA
CTACATTGATAAGGCCTTGTCGGCAGAGGAGTTTGAGTCTCGTATCGAGACAGCTCTTCTCTATGCCGATAGTCAAGACA
GCAAAAGCCTGGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCTCAATTCCAGTATCCTTTTAAAGAGGTTTACTAT
CTCGAAACGTCCCCAAGACCCCATCGTGTTATTCTCTATACCAAGACGGATAGGCTGGAATTTACGGCGAGTCTAGAGGA
GGTTCTCAAGCAGGAGCCTCGTCTCTTGCAGTGTCATCGTTCTTTTCTCATCAATCCAGCCAATGTAGTGCATTTGGATA
AGAAAGAAAAACTGCTTTTCTTTGCCAATGGTGGAAGTTGTCTAATCGCGCGTTATAAGGTTAGGGAAGTGTCTGAGGCT
ATCAATAATTTGCATTGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-241)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

52.893

98.776

0.522
  comE/comE1 Streptococcus equinus JB1

43.46

96.735

0.42
  comE/comE2 Streptococcus equinus JB1

38.43

98.776

0.38

Multiple sequence alignment