Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   ACJEHS_RS00865 Genome accession   NZ_CP174225
Coordinates   191347..192024 (-) Length   225 a.a.
NCBI ID   WP_011213604.1    Uniprot ID   -
Organism   Legionella pneumophila strain SPF641     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 186347..197024
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJEHS_RS00840 (ACJEHS_00840) ruvC 186542..187066 (+) 525 WP_010947018.1 crossover junction endodeoxyribonuclease RuvC -
  ACJEHS_RS00845 (ACJEHS_00845) ruvA 187063..187662 (+) 600 WP_010947019.1 Holliday junction branch migration protein RuvA -
  ACJEHS_RS00850 (ACJEHS_00850) - 187712..188032 (+) 321 WP_010947020.1 hypothetical protein -
  ACJEHS_RS00855 (ACJEHS_00855) lem8 188065..189651 (-) 1587 WP_010947021.1 Dot/Icm T4SS effector Lem8 -
  ACJEHS_RS00860 (ACJEHS_00860) - 189935..191350 (-) 1416 WP_010947022.1 ATP-binding protein -
  ACJEHS_RS00865 (ACJEHS_00865) ciaR 191347..192024 (-) 678 WP_011213604.1 response regulator Regulator
  ACJEHS_RS00870 (ACJEHS_00870) - 192085..192630 (-) 546 WP_010947024.1 septation protein A -
  ACJEHS_RS00875 (ACJEHS_00875) - 192873..194312 (-) 1440 WP_010947025.1 LysM peptidoglycan-binding domain-containing protein -
  ACJEHS_RS00880 (ACJEHS_00880) gloB 194427..195191 (-) 765 WP_010947026.1 hydroxyacylglutathione hydrolase -
  ACJEHS_RS00885 (ACJEHS_00885) - 195195..196043 (-) 849 WP_015444565.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  ACJEHS_RS00890 (ACJEHS_00890) - 196319..196528 (+) 210 WP_011213609.1 hypothetical protein -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25151.74 Da        Isoelectric Point: 4.9981

>NTDB_id=963152 ACJEHS_RS00865 WP_011213604.1 191347..192024(-) (ciaR) [Legionella pneumophila strain SPF641]
MRLLLVEDDELLGDAVKAGLTQFGYVVDWLKDGEAARAALKSESFELIILDLGLPKLSGLSLLQNIRHDGNSTPVIILTA
RESIEDRVKGLDSGADDYLIKPFDLNELSARIRALVRRSQGRADSVLQYKNITLDPAAHSVFVDDVLVNVPRREFALLQK
LLENSGQVLSREQLMQSIYGWEEDVDSNALEVHIHNLRKKLNANFIRTIRGVGYMAEKNDSVLLS

Nucleotide


Download         Length: 678 bp        

>NTDB_id=963152 ACJEHS_RS00865 WP_011213604.1 191347..192024(-) (ciaR) [Legionella pneumophila strain SPF641]
ATGAGATTATTACTTGTTGAAGACGATGAACTGCTTGGCGATGCAGTAAAAGCCGGACTGACACAATTTGGTTATGTTGT
TGACTGGCTAAAAGATGGCGAAGCTGCTCGGGCGGCTCTCAAATCAGAGTCTTTTGAATTAATTATTCTTGACTTGGGAT
TACCTAAATTATCCGGTTTATCATTATTGCAAAACATCAGACATGATGGAAATAGCACACCTGTGATTATTCTTACAGCT
CGAGAATCAATAGAAGATCGGGTAAAAGGCTTAGATAGCGGTGCTGACGATTATCTTATTAAGCCTTTTGATTTAAACGA
ATTAAGTGCAAGGATTAGAGCATTGGTAAGGCGCTCTCAGGGCAGAGCTGATTCCGTGTTGCAATATAAAAATATTACTC
TCGATCCTGCTGCTCATTCTGTCTTCGTGGATGATGTACTCGTCAATGTTCCAAGAAGAGAATTTGCTCTATTGCAGAAA
TTACTTGAAAACAGTGGCCAGGTTTTATCTCGAGAACAATTAATGCAGAGTATTTATGGCTGGGAAGAAGACGTGGACAG
TAATGCTCTCGAAGTTCATATACATAATTTACGTAAAAAACTTAACGCAAACTTTATCCGCACTATACGTGGTGTAGGAT
ATATGGCTGAAAAAAATGACAGTGTACTTCTATCGTGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(148-215)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.356

97.333

0.373
  ciaR Streptococcus pneumoniae D39

38.356

97.333

0.373
  ciaR Streptococcus pneumoniae R6

38.356

97.333

0.373
  ciaR Streptococcus pneumoniae TIGR4

38.356

97.333

0.373
  ciaR Streptococcus mutans UA159

37.9

97.333

0.369
  micA Streptococcus pneumoniae Cp1015

35.345

100

0.364