Detailed information NTG0962844

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: ACJEHX_RS09125
• Genome accession: NZ_CP174220
• Coordinates: 2050727..2052001 (-)
• Length: 424 a.a.
• NCBI ID: WP_015444406.1
• Uniprot ID: Q5ZUE0
• Organism: Legionella pneumophila strain SPF647
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2045727..2057001

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACJEHX_RS09115 (ACJEHX_09115)	-	2047632..2047910 (-)	279	WP_011214112.1	HU family DNA-binding protein	-
ACJEHX_RS09120 (ACJEHX_09120)	lon	2048039..2050489 (-)	2451	WP_010947583.1	endopeptidase La	-
ACJEHX_RS09125 (ACJEHX_09125)	clpX	2050727..2052001 (-)	1275	WP_015444406.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ACJEHX_RS09130 (ACJEHX_09130)	clpP	2052142..2052786 (-)	645	WP_010947585.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	-
ACJEHX_RS09135 (ACJEHX_09135)	tig	2052789..2054120 (-)	1332	WP_010947586.1	trigger factor	-
ACJEHX_RS09160 (ACJEHX_09160)	-	2054982..2056208 (+)	1227	WP_010947587.1	site-specific integrase	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 46583.17 Da
• Isoelectric Point: 5.1603

>NTDB_id=962844 ACJEHX_RS09125 WP_015444406.1 2050727..2052001(-) (clpX) [Legionella pneumophila strain SPF647]
MSKSGNGNGDKVLYCSFCGKSQHEVKKLIAGPSVFVCDECVELCNDIIREETHETHEETEARLPTPKEISNFLDEYVIGQ
QHAKKVLSVAVYNHYKRLQHKSEDGVELGKSNILLIGPTGSGKTLLAQTLARILNVPFAMADATTLTEAGYVGEDVENII
QKLLQKCDYDVDKAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTSN
ILFICGGAFAGLDKVIRERSDKSSIGFSAQLKSKKSSNDEVSKVLGQLESDDLIKYGLIPEFVGRLPVVTTLQELDEAAL
IDILTRPKNALTKQFQSLFKMEGSELEFRGEALIAIAKKALERKMGARGLRSILENILLDTMYDLPSLEGVNKVVIDESV
VNGLSKPILIYEQDEKKSASGSKD

Nucleotide

• Length: 1275 bp

>NTDB_id=962844 ACJEHX_RS09125 WP_015444406.1 2050727..2052001(-) (clpX) [Legionella pneumophila strain SPF647]
ATGAGTAAATCCGGTAACGGAAATGGAGATAAGGTCTTATATTGCTCTTTTTGTGGCAAGAGTCAACATGAGGTAAAAAA
ATTAATTGCTGGACCTTCTGTGTTTGTTTGTGATGAATGTGTAGAGCTTTGTAATGATATTATTCGAGAAGAGACGCATG
AAACTCATGAAGAAACTGAGGCACGTCTACCGACACCAAAAGAAATATCTAACTTTCTCGATGAATACGTAATAGGGCAA
CAACATGCCAAAAAGGTTTTATCAGTAGCAGTATATAATCACTATAAGAGATTACAGCATAAAAGCGAGGATGGTGTTGA
GCTCGGCAAAAGTAATATTTTACTTATAGGACCTACTGGCAGTGGTAAGACTCTTTTAGCTCAAACCCTGGCGCGGATTC
TTAATGTTCCTTTTGCCATGGCTGATGCCACGACCCTTACTGAAGCTGGATATGTTGGCGAAGACGTTGAAAATATTATC
CAGAAGTTATTACAGAAGTGCGACTATGATGTAGATAAGGCACAGCAAGGTATTGTCTATATCGACGAAATCGATAAGAT
TTCACGCAAATCAGATAATCCATCTATCACCAGAGATGTTTCAGGAGAAGGTGTTCAACAAGCTTTACTGAAATTAATTG
AAGGTACTGTTGCATCTGTTCCACCGCAAGGTGGGCGAAAGCATCCACAGCAGGAATTTTTGCAGGTAGATACATCAAAT
ATTTTATTTATCTGTGGTGGCGCTTTTGCAGGTTTGGACAAAGTAATACGTGAACGCAGCGATAAATCAAGCATAGGTTT
TTCTGCTCAATTAAAAAGCAAAAAAAGCAGTAATGATGAAGTTTCAAAAGTTTTAGGTCAATTGGAATCAGATGATTTAA
TTAAATATGGGTTGATTCCCGAGTTTGTTGGACGTTTGCCTGTTGTAACCACTTTACAGGAACTTGATGAAGCGGCATTG
ATTGATATATTAACGAGACCTAAGAATGCTTTAACAAAGCAATTTCAATCACTTTTCAAAATGGAAGGTTCTGAACTTGA
GTTTAGAGGCGAAGCTTTGATTGCTATTGCTAAAAAGGCCCTCGAAAGAAAAATGGGCGCAAGAGGTTTGCGATCAATAC
TTGAAAATATTCTTTTAGACACTATGTATGACTTACCTTCCTTGGAAGGCGTGAATAAGGTTGTTATTGATGAGAGTGTA
GTGAATGGACTATCTAAACCGATTCTCATTTATGAACAGGATGAGAAAAAAAGTGCGTCTGGTAGTAAAGATTAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-308)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (315-387)

• ClpX C4-type zinc finger (zf-C4_ClpX) (13-50)

3D structure

• AlphaFold DB: Q5ZUE0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	59.658	96.462	0.575
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	54.926	95.755	0.526