Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   AABJ45_RS10725 Genome accession   NZ_AP028611
Coordinates   2079475..2079969 (-) Length   164 a.a.
NCBI ID   WP_223842497.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain Sep6     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2074475..2084969
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABJ45_RS10695 (TKY121527_20830) - 2074784..2075659 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  AABJ45_RS10700 (TKY121527_20840) pstC 2075777..2076640 (+) 864 WP_000165887.1 phosphate ABC transporter permease subunit PstC -
  AABJ45_RS10705 (TKY121527_20850) pstA 2076633..2077448 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  AABJ45_RS10710 (TKY121527_20860) pstB 2077450..2078202 (+) 753 WP_000536449.1 phosphate ABC transporter ATP-binding protein PstB -
  AABJ45_RS10715 (TKY121527_20870) phoU 2078217..2078867 (+) 651 WP_001245781.1 phosphate signaling complex protein PhoU -
  AABJ45_RS10720 (TKY121527_20880) - 2078929..2079360 (+) 432 Protein_2073 transposase -
  AABJ45_RS10725 (TKY121527_20890) comR 2079475..2079969 (-) 495 WP_223842497.1 helix-turn-helix transcriptional regulator Regulator
  AABJ45_RS10730 (TKY121527_20900) - 2080127..2081143 (+) 1017 WP_000415103.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  AABJ45_RS10735 (TKY121527_20910) galU 2081165..2082064 (+) 900 WP_000202234.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  AABJ45_RS10740 (TKY121527_20920) - 2082482..2083423 (+) 942 WP_000428163.1 hypothetical protein -
  AABJ45_RS10745 (TKY121527_20930) - 2083525..2083710 (-) 186 WP_000693096.1 hypothetical protein -
  AABJ45_RS10750 (TKY121527_20940) - 2083724..2084401 (-) 678 WP_000658497.1 rhomboid family intramembrane serine protease -
  AABJ45_RS10755 (TKY121527_20950) - 2084385..2084924 (-) 540 WP_000834312.1 5-formyltetrahydrofolate cyclo-ligase -

Sequence

Protein


Download         Length: 164 a.a.        Molecular weight: 19708.79 Da        Isoelectric Point: 5.0076

>NTDB_id=96256 AABJ45_RS10725 WP_223842497.1 2079475..2079969(-) (comR) [Streptococcus pneumoniae strain Sep6]
MIQYMLIIEVNNSGSSCRLREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRPILTKLKYIAERLGVEDYK
LMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVFDKIFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEI
LSFW

Nucleotide


Download         Length: 495 bp        

>NTDB_id=96256 AABJ45_RS10725 WP_223842497.1 2079475..2079969(-) (comR) [Streptococcus pneumoniae strain Sep6]
TTGATTCAGTATATGCTTATAATAGAGGTAAACAACTCAGGAAGTTCTTGTAGGTTGCGAGAGTTTGGCGAAAAAATTAA
AAGATTACGTTTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTCTGAATTAAGTATCCGTCAATTAATTA
GAATTGAAAATGGAGAATCCAGACCAATACTAACAAAGTTAAAATATATTGCTGAACGTTTGGGGGTTGAAGATTACAAG
TTGATGCCAAGTTATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTCTTGATGAGGACTCCTACATACGAAGA
TGAAACTATCGCCCAAAAGAAAGAGAGTGTTTTTGATAAGATTTTTGAAGAGTATTATGATAGGCTACCTGAGGAAGAAA
GATTTATCATCCCAAATTATTCATATCTGGCACTAACGAACTACACAGTTCAAAAATTACCAGAAAAGCTAGTTGAAATA
CTGTCCTTCTGGTGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(90-137)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

55.833

73.171

0.409
  comR Streptococcus pyogenes MGAS315

54.167

73.171

0.396
  comR Streptococcus mutans UA159

53.333

73.171

0.39
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

54.545

67.073

0.366