Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   OO841_RS21265 Genome accession   NZ_AP026087
Coordinates   4175709..4176833 (-) Length   374 a.a.
NCBI ID   WP_000228545.1    Uniprot ID   A0AAV3H2U0
Organism   Escherichia coli strain 8_140198     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 4175709..4185371 4175709..4176833 within 0


Gene organization within MGE regions


Location: 4175709..4185371
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OO841_RS21265 (CL8NIID8_40860) dprA 4175709..4176833 (-) 1125 WP_000228545.1 DNA-protecting protein DprA Machinery gene
  OO841_RS21270 (CL8NIID8_40870) def 4176963..4177472 (+) 510 WP_000114984.1 peptide deformylase -
  OO841_RS21275 (CL8NIID8_40880) fmt 4177487..4178434 (+) 948 WP_000004459.1 methionyl-tRNA formyltransferase -
  OO841_RS21280 (CL8NIID8_40890) rsmB 4178480..4179769 (+) 1290 WP_001301795.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  OO841_RS21285 (CL8NIID8_40900) trkA 4179791..4181167 (+) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  OO841_RS21290 (CL8NIID8_40910) mscL 4181297..4181707 (+) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -
  OO841_RS21295 (CL8NIID8_40920) arfA 4181704..4181922 (-) 219 WP_000092696.1 alternative ribosome-rescue factor ArfA -
  OO841_RS21300 (CL8NIID8_40930) zntR 4181978..4182403 (-) 426 WP_000285607.1 Zn(2+)-responsive transcriptional regulator -
  OO841_RS21305 (CL8NIID8_40940) yhdN 4182414..4182782 (-) 369 WP_000266488.1 DUF1992 domain-containing protein -
  OO841_RS21310 (CL8NIID8_40950) rplQ 4182889..4183272 (-) 384 WP_001216368.1 50S ribosomal protein L17 -
  OO841_RS21315 (CL8NIID8_40960) rpoA 4183313..4184302 (-) 990 WP_001162094.1 DNA-directed RNA polymerase subunit alpha -
  OO841_RS21320 (CL8NIID8_40970) rpsD 4184328..4184948 (-) 621 WP_000135224.1 30S ribosomal protein S4 -
  OO841_RS21325 (CL8NIID8_40980) rpsK 4184982..4185371 (-) 390 WP_001029684.1 30S ribosomal protein S11 -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 41034.02 Da        Isoelectric Point: 6.3845

>NTDB_id=95782 OO841_RS21265 WP_000228545.1 4175709..4176833(-) (dprA) [Escherichia coli strain 8_140198]
MVDTEIWLRLMSISSLYGDDMVRIAHWLARQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLAKHGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGRPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=95782 OO841_RS21265 WP_000228545.1 4175709..4176833(-) (dprA) [Escherichia coli strain 8_140198]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAGACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGGAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGTGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGAAGCATGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT
TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGAGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCGACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterproScan.

DprA winged helix domain (DprA_WH)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.78

98.663

0.481
  dprA Glaesserella parasuis strain SC1401

45.401

90.107

0.409
  dprA Vibrio cholerae strain A1552

49.355

82.888

0.409
  dprA Haemophilus influenzae Rd KW20

44.214

90.107

0.398
  dprA Legionella pneumophila strain ERS1305867

44.545

88.235

0.393

Multiple sequence alignment