Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   ACIVIR_RS10325 Genome accession   NZ_CP173225
Coordinates   2007008..2007667 (+) Length   219 a.a.
NCBI ID   WP_000565001.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 262     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2002008..2012667
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACIVIR_RS10300 - 2002313..2002630 (-) 318 WP_050221104.1 PTS sugar transporter subunit IIB -
  ACIVIR_RS10305 - 2002645..2003541 (-) 897 WP_001865114.1 hypothetical protein -
  ACIVIR_RS10310 - 2003544..2004806 (-) 1263 WP_000413342.1 PTS sugar transporter subunit IIC -
  ACIVIR_RS10315 - 2005086..2006264 (+) 1179 WP_001865373.1 ROK family transcriptional regulator -
  ACIVIR_RS10320 - 2006492..2006938 (-) 447 WP_000155432.1 GNAT family N-acetyltransferase -
  ACIVIR_RS10325 cclA/cilC 2007008..2007667 (+) 660 WP_000565001.1 A24 family peptidase Machinery gene
  ACIVIR_RS10330 - 2007719..2008870 (-) 1152 WP_001865397.1 XRE family transcriptional regulator -
  ACIVIR_RS10335 - 2008885..2009616 (-) 732 WP_000934016.1 hypothetical protein -
  ACIVIR_RS10340 - 2009836..2009946 (+) 111 Protein_2002 prepilin peptidase -
  ACIVIR_RS10345 trpA 2009918..2010694 (-) 777 WP_001127027.1 tryptophan synthase subunit alpha -
  ACIVIR_RS10350 trpB 2010687..2011910 (-) 1224 WP_024477621.1 tryptophan synthase subunit beta -
  ACIVIR_RS10355 - 2011888..2012487 (-) 600 WP_000169888.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24820.92 Da        Isoelectric Point: 7.2761

>NTDB_id=957289 ACIVIR_RS10325 WP_000565001.1 2007008..2007667(+) (cclA/cilC) [Streptococcus pneumoniae strain 262]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=957289 ACIVIR_RS10325 WP_000565001.1 2007008..2007667(+) (cclA/cilC) [Streptococcus pneumoniae strain 262]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTAGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
ATACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATTGATATCCGCATGGGTGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterProScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

98.174

100

0.982
  cclA/cilC Streptococcus pneumoniae Rx1

96.804

100

0.968
  cclA/cilC Streptococcus pneumoniae D39

96.804

100

0.968
  cclA/cilC Streptococcus pneumoniae R6

96.804

100

0.968
  cclA/cilC Streptococcus mitis SK321

92.237

100

0.922
  cclA/cilC Streptococcus mitis NCTC 12261

87.215

100

0.872