Detailed information NTG0095288

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: QML92_RS07895
• Genome accession: NZ_AP025937
• Coordinates: 1580274..1580933 (+)
• Length: 219 a.a.
• NCBI ID: WP_000565023.1
• Uniprot ID: A0A0I8D2P0
• Organism: Streptococcus pneumoniae strain PZ900700792
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1575274..1585933

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QML92_RS07870 (PC0780_15680)	-	1575579..1575896 (-)	318	WP_001151646.1	PTS sugar transporter subunit IIB	-
QML92_RS07875 (PC0780_15690)	-	1575911..1576807 (-)	897	WP_000825669.1	PEP phosphonomutase	-
QML92_RS07880 (PC0780_15700)	-	1576810..1578072 (-)	1263	WP_000413336.1	PTS sugar transporter subunit IIC	-
QML92_RS07885 (PC0780_15710)	-	1578352..1579530 (+)	1179	WP_000175880.1	ROK family transcriptional regulator	-
QML92_RS07890 (PC0780_15720)	-	1579758..1580204 (-)	447	WP_000155406.1	GNAT family N-acetyltransferase	-
QML92_RS07895 (PC0780_15730)	cclA/cilC	1580274..1580933 (+)	660	WP_000565023.1	A24 family peptidase	Machinery gene
QML92_RS07900 (PC0780_15740)	trpA	1580905..1581681 (-)	777	WP_001127007.1	tryptophan synthase subunit alpha	-
QML92_RS07905 (PC0780_15750)	trpB	1581674..1582897 (-)	1224	WP_000331298.1	tryptophan synthase subunit beta	-
QML92_RS07910 (PC0780_15760)	-	1582875..1583474 (-)	600	WP_000169872.1	phosphoribosylanthranilate isomerase	-
QML92_RS07915 (PC0780_15770)	trpC	1583461..1584228 (-)	768	WP_000076544.1	indole-3-glycerol phosphate synthase TrpC	-
QML92_RS07920 (PC0780_15780)	trpD	1584225..1585229 (-)	1005	WP_000658685.1	anthranilate phosphoribosyltransferase	-
QML92_RS07925 (PC0780_15790)	-	1585240..1585806 (-)	567	WP_000601921.1	aminodeoxychorismate/anthranilate synthase component II	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24921.13 Da
• Isoelectric Point: 8.2409

>NTDB_id=95288 QML92_RS07895 WP_000565023.1 1580274..1580933(+) (cclA/cilC) [Streptococcus pneumoniae strain PZ900700792]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLG
LLFLLYSWKLLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=95288 QML92_RS07895 WP_000565023.1 1580274..1580933(+) (cclA/cilC) [Streptococcus pneumoniae strain PZ900700792]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAGTCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGAAATTGCTTTCCTTGGGGCAAGTAGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

3D structure

• AlphaFold DB: A0A0I8D2P0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae TIGR4	97.717	100	0.977
cclA/cilC	Streptococcus pneumoniae Rx1	96.347	100	0.963
cclA/cilC	Streptococcus pneumoniae D39	96.347	100	0.963
cclA/cilC	Streptococcus pneumoniae R6	96.347	100	0.963
cclA/cilC	Streptococcus mitis SK321	92.237	100	0.922
cclA/cilC	Streptococcus mitis NCTC 12261	86.301	100	0.863