Detailed information NTG0949092

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXR38_RS09480
• Genome accession: NZ_CP147872
• Coordinates: 1946302..1947345 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN131
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1941302..1952345

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR38_RS09450 (UXR38_09450)	-	1941723..1942979 (-)	1257	WP_336469804.1	aminopeptidase	-
UXR38_RS09455 (UXR38_09455)	-	1942982..1943182 (-)	201	WP_000180460.1	DUF1128 family protein	-
UXR38_RS09460 (UXR38_09460)	-	1943329..1943793 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
UXR38_RS09465 (UXR38_09465)	-	1943800..1944075 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXR38_RS09470 (UXR38_09470)	-	1944353..1945570 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
UXR38_RS09475 (UXR38_09475)	vraR	1945683..1946312 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
UXR38_RS09480 (UXR38_09480)	vraS	1946302..1947345 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXR38_RS09485 (UXR38_09485)	liaF	1947342..1948043 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXR38_RS09490 (UXR38_09490)	-	1948058..1948444 (-)	387	Protein_1828	hypothetical protein	-
UXR38_RS09495 (UXR38_09495)	map	1948661..1949419 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
UXR38_RS09500 (UXR38_09500)	-	1949950..1950936 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
UXR38_RS09505 (UXR38_09505)	-	1951367..1951780 (-)	414	WP_001557448.1	hypothetical protein	-
UXR38_RS09510 (UXR38_09510)	-	1951809..1951919 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=949092 UXR38_RS09480 WP_001017131.1 1946302..1947345(-) (vraS) [Staphylococcus aureus strain BSN131]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=949092 UXR38_RS09480 WP_001017131.1 1946302..1947345(-) (vraS) [Staphylococcus aureus strain BSN131]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1