Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   ACG3JE_RS00210 Genome accession   NZ_CP171736
Coordinates   40686..41741 (+) Length   351 a.a.
NCBI ID   WP_013794421.1    Uniprot ID   -
Organism   Streptococcus parauberis strain DB-M17     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 35686..46741
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACG3JE_RS00200 (ACG3JE_00200) - 39406..39798 (+) 393 WP_013794422.1 DUF1033 family protein -
  ACG3JE_RS00205 (ACG3JE_00205) comGA 39833..40774 (+) 942 WP_003108751.1 competence type IV pilus ATPase ComGA Machinery gene
  ACG3JE_RS00210 (ACG3JE_00210) comGB 40686..41741 (+) 1056 WP_013794421.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACG3JE_RS00215 (ACG3JE_00215) - 41818..43253 (-) 1436 Protein_26 recombinase family protein -
  ACG3JE_RS00220 (ACG3JE_00220) - 43374..43691 (-) 318 WP_041828635.1 hypothetical protein -
  ACG3JE_RS00225 (ACG3JE_00225) - 43696..44103 (-) 408 WP_041828634.1 hypothetical protein -
  ACG3JE_RS00230 (ACG3JE_00230) - 44129..44719 (-) 591 WP_013794419.1 hypothetical protein -
  ACG3JE_RS00235 (ACG3JE_00235) - 44721..44894 (-) 174 WP_192813189.1 hypothetical protein -
  ACG3JE_RS00240 (ACG3JE_00240) - 44908..45597 (-) 690 WP_013794418.1 LexA family transcriptional regulator -
  ACG3JE_RS00245 (ACG3JE_00245) - 45866..46069 (+) 204 WP_003108729.1 helix-turn-helix domain-containing protein -
  ACG3JE_RS00250 (ACG3JE_00250) - 46106..46288 (+) 183 WP_003108726.1 hypothetical protein -

Sequence

Protein


Download         Length: 351 a.a.        Molecular weight: 40401.47 Da        Isoelectric Point: 9.8708

>NTDB_id=948799 ACG3JE_RS00210 WP_013794421.1 40686..41741(+) (comGB) [Streptococcus parauberis strain DB-M17]
MKNGIKLLISWLQKDISLKKKGKKKRLSSKKQYQLIQLLHNLQASGFNLVEMVSFLKKSKLISEEQVKIMEFHMLNGSSL
SKIMLDLGYPDSIITQLSLAELHGNILGSLENIETYLLQVNHIKKKTFEVVMYPLVLLFFLTTILLGLRQYLLPSLNEEG
PLMFLLTYFPHLLIILIVIILFVSIVVIYKWRHSSPLKLISQISRLPLIGYVIQLYMTAFYAREWGNLLDQGLELSTILS
VMSKEKSLLVREIGIEMNSAFVEGIPFEKKVLDYPFFKNELSLIISYGQVKSKLGKELEIYSQNTWESYFRFLIQLTQLI
QPIVFLAVALIIVMIYAAMLLPIYQNMGGNL

Nucleotide


Download         Length: 1056 bp        

>NTDB_id=948799 ACG3JE_RS00210 WP_013794421.1 40686..41741(+) (comGB) [Streptococcus parauberis strain DB-M17]
ATGAAAAATGGAATCAAGCTATTGATCAGTTGGTTGCAAAAGGACATTTCCCTGAAGAAAAAGGGGAAAAAGAAAAGATT
ATCGAGTAAAAAACAATATCAACTTATCCAATTGTTACATAATCTCCAAGCAAGCGGATTTAATTTAGTTGAAATGGTAT
CTTTTCTGAAGAAAAGTAAATTAATATCTGAAGAGCAGGTTAAAATTATGGAATTTCACATGCTCAATGGCAGTAGTTTA
TCAAAAATCATGCTTGATTTAGGTTACCCAGATAGTATTATAACTCAATTGAGTTTAGCAGAATTACATGGGAATATTTT
GGGGAGTCTTGAAAATATAGAAACATACCTTTTGCAAGTGAATCATATTAAAAAGAAAACTTTCGAAGTGGTAATGTATC
CACTTGTATTACTATTTTTTCTAACAACTATACTACTTGGTTTGAGACAATATTTATTGCCTTCGCTTAATGAGGAAGGT
CCACTTATGTTCCTACTAACCTATTTTCCTCACCTTTTAATAATCCTAATTGTGATAATCCTCTTTGTCTCTATAGTAGT
TATTTATAAATGGCGACACAGTTCACCACTCAAGCTAATTAGCCAAATTAGTCGATTGCCTTTAATAGGATACGTCATCC
AGCTATATATGACAGCCTTCTATGCTCGAGAATGGGGAAATTTATTAGATCAGGGGCTTGAATTAAGTACGATTTTGTCT
GTTATGAGTAAGGAAAAATCACTTTTGGTACGGGAAATAGGTATAGAAATGAATAGTGCTTTTGTAGAGGGGATTCCGTT
TGAGAAAAAGGTACTAGATTATCCATTTTTTAAAAATGAATTGAGTTTAATTATTTCATATGGACAAGTTAAATCAAAAT
TAGGGAAGGAGTTAGAAATATATTCTCAAAATACATGGGAGTCTTACTTCAGGTTCCTCATACAACTTACTCAGCTGATT
CAACCAATTGTATTTTTAGCAGTTGCTCTAATTATTGTCATGATTTATGCAGCAATGCTATTGCCAATTTATCAAAATAT
GGGAGGAAATTTATGA

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(36-154)

Type II secretion system (T2SS), protein F (T2SSF)

(222-342)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Streptococcus mutans UA140

51.014

98.291

0.501
  comGB Streptococcus mutans UA159

51.014

98.291

0.501
  comGB Streptococcus gordonii str. Challis substr. CH1

46.765

96.866

0.453
  comGB/cglB Streptococcus mitis NCTC 12261

46.176

96.866

0.447
  comGB/cglB Streptococcus mitis SK321

44.807

96.011

0.43
  comGB/cglB Streptococcus pneumoniae Rx1

44.51

96.011

0.427
  comGB/cglB Streptococcus pneumoniae D39

44.51

96.011

0.427
  comGB/cglB Streptococcus pneumoniae R6

44.51

96.011

0.427
  comGB/cglB Streptococcus pneumoniae TIGR4

44.51

96.011

0.427
  comGB Lactococcus lactis subsp. cremoris KW2

41.935

97.151

0.407