Detailed information NTG0948313

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: WDV79_RS02925
• Genome accession: NZ_CP147731
• Coordinates: 588966..589808 (-)
• Length: 280 a.a.
• NCBI ID: WP_001015240.1
• Uniprot ID: Q8DZU1
• Organism: Streptococcus agalactiae strain SagR266
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 583966..594808

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WDV79_RS02915 (WDV79_02915)	-	585914..586615 (-)	702	WP_000120355.1	ABC transporter ATP-binding protein	-
WDV79_RS02920 (WDV79_02920)	topA	586752..588871 (-)	2120	Protein_580	type I DNA topoisomerase	-
WDV79_RS02925 (WDV79_02925)	dprA	588966..589808 (-)	843	WP_001015240.1	DNA-processing protein DprA	Machinery gene
WDV79_RS02930 (WDV79_02930)	-	589946..590974 (-)	1029	WP_000162771.1	siderophore ABC transporter substrate-binding protein	-
WDV79_RS02935 (WDV79_02935)	-	591036..591797 (-)	762	WP_000614752.1	ATP-binding cassette domain-containing protein	-
WDV79_RS02940 (WDV79_02940)	-	591794..592768 (-)	975	WP_000588576.1	iron chelate uptake ABC transporter family permease subunit	-
WDV79_RS02945 (WDV79_02945)	-	592765..593727 (-)	963	WP_000735588.1	iron chelate uptake ABC transporter family permease subunit	-
WDV79_RS02950 (WDV79_02950)	-	593966..594514 (-)	549	WP_000136509.1	sugar O-acetyltransferase	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31294.36 Da
• Isoelectric Point: 9.3802

>NTDB_id=948313 WDV79_RS02925 WP_001015240.1 588966..589808(-) (dprA) [Streptococcus agalactiae strain SagR266]
MNHFELFKLKKAGLTNLNIHNIINYLKKNSLTSLSVRNMAVVSKCKNPTFFIENYKQLDLKKLRQEFKKFPVLSILDSNY
PLELKEIYNPPVLLFYQGNIELLSKPKLAVVGARQASQIGCQSVKKIIKETNNQFVIVSGLARGIDTAAHVSALKNGGSS
IAVIGSGLDVYYPTENKKLQEYMSYNHLVLSEYFTGEQPLKFHFPERNRIIAGLCQGIVVAEAKMRSGSLITCERALEEG
REVFAIPGNIIDGKSDGCHHLIQEGAKCIISGKDILSEYQ

Nucleotide

• Length: 843 bp

>NTDB_id=948313 WDV79_RS02925 WP_001015240.1 588966..589808(-) (dprA) [Streptococcus agalactiae strain SagR266]
ATGAATCATTTTGAACTATTTAAGCTTAAAAAAGCTGGATTAACAAATCTTAATATCCACAATATTATCAACTATCTCAA
AAAGAATAGTTTAACTTCTCTATCTGTTCGCAATATGGCCGTAGTATCAAAATGTAAAAATCCTACTTTCTTTATAGAAA
ATTATAAACAGCTAGACCTTAAAAAACTTCGACAAGAATTCAAAAAATTTCCAGTTCTATCGATTTTGGATTCTAACTAT
CCTTTAGAGTTAAAAGAAATATATAATCCACCAGTTCTACTTTTTTATCAGGGTAATATTGAACTTCTATCTAAACCTAA
ATTAGCTGTAGTGGGGGCAAGACAGGCATCTCAGATAGGTTGTCAGTCTGTTAAAAAGATTATCAAGGAGACTAACAATC
AATTTGTTATCGTAAGTGGTTTAGCGCGTGGCATTGATACAGCAGCACATGTTAGTGCTTTAAAAAATGGCGGCAGTAGT
ATAGCTGTTATCGGGAGTGGTTTAGATGTTTATTATCCAACGGAGAATAAGAAACTTCAAGAATATATGTCATATAATCA
TCTCGTATTATCAGAATATTTTACCGGAGAACAACCCTTGAAATTTCATTTCCCCGAACGTAACCGTATTATTGCAGGGC
TGTGTCAAGGTATTGTGGTTGCCGAAGCTAAGATGAGATCTGGAAGTTTAATTACCTGTGAAAGAGCATTAGAAGAGGGA
CGAGAAGTTTTTGCCATTCCCGGAAATATTATCGATGGCAAATCAGATGGATGCCACCATCTTATCCAAGAAGGAGCTAA
ATGCATTATTTCAGGAAAAGATATCCTTTCTGAATATCAGTAG

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (69-270)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-63)

3D structure

• AlphaFold DB: Q8DZU1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	70.251	99.643	0.7
dprA/cilB/dalA	Streptococcus mitis SK321	62.5	100	0.625
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	61.786	100	0.618
dprA/cilB/dalA	Streptococcus pneumoniae D39	61.786	100	0.618
dprA/cilB/dalA	Streptococcus pneumoniae R6	61.786	100	0.618
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	61.786	100	0.618
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	61.429	100	0.614
dprA	Lactococcus lactis subsp. cremoris KW2	60.932	99.643	0.607
dprA	Latilactobacillus sakei subsp. sakei 23K	42.231	89.643	0.379