Detailed information    

insolico Bioinformatically predicted

Overview


Name   comEA   Type   Machinery gene
Locus tag   V4Q90_RS12290 Genome accession   NZ_CP146990
Coordinates   2764155..2764472 (+) Length   105 a.a.
NCBI ID   WP_010946546.1    Uniprot ID   Q5ZXC2
Organism   Legionella pneumophila strain LEG1116     
Function   dsDNA binding (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 2759155..2769472
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V4Q90_RS12270 (V4Q90_12235) - 2759307..2760746 (+) 1440 WP_010946542.1 cation:proton antiporter -
  V4Q90_RS12275 (V4Q90_12240) nadC 2760743..2761585 (+) 843 WP_010946543.1 carboxylating nicotinate-nucleotide diphosphorylase -
  V4Q90_RS12280 (V4Q90_12245) - 2761582..2762673 (+) 1092 WP_010946544.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -
  V4Q90_RS12285 (V4Q90_12250) - 2762648..2764063 (+) 1416 WP_010946545.1 M20 family metallopeptidase -
  V4Q90_RS12290 (V4Q90_12255) comEA 2764155..2764472 (+) 318 WP_010946546.1 helix-hairpin-helix domain-containing protein Machinery gene
  V4Q90_RS12295 (V4Q90_12260) - 2764668..2765705 (+) 1038 WP_350534582.1 rod shape-determining protein -
  V4Q90_RS12300 (V4Q90_12265) mreC 2765683..2766591 (+) 909 WP_010946548.1 rod shape-determining protein MreC -
  V4Q90_RS12305 (V4Q90_12270) mreD 2766588..2767067 (+) 480 WP_010946549.1 rod shape-determining protein MreD -
  V4Q90_RS12310 (V4Q90_12275) - 2767003..2767605 (-) 603 WP_011213321.1 pseudouridine synthase -
  V4Q90_RS12315 (V4Q90_12280) - 2767866..2768564 (+) 699 WP_010946551.1 hypothetical protein -

Sequence


Protein


Download         Length: 105 a.a.        Molecular weight: 11773.78 Da        Isoelectric Point: 10.5233

>NTDB_id=945434 V4Q90_RS12290 WP_010946546.1 2764155..2764472(+) (comEA) [Legionella pneumophila strain LEG1116]
MKARLIAILLSFIVIPFSSQAENEPQKTPAKQVLVKGKINLNTADVYSLTGSFKGIGKKRAEAIIAYRENHQGFKSLEEL
AEVKGIGQRFVDKNREKLKEIFVIN

Nucleotide


Download         Length: 318 bp        

>NTDB_id=945434 V4Q90_RS12290 WP_010946546.1 2764155..2764472(+) (comEA) [Legionella pneumophila strain LEG1116]
ATGAAAGCAAGACTCATTGCTATTTTATTGTCATTTATTGTTATCCCTTTCTCTTCTCAAGCTGAGAACGAGCCTCAAAA
AACTCCAGCTAAACAAGTCCTTGTTAAGGGCAAGATTAATCTTAATACAGCGGATGTGTATTCTTTAACAGGCTCTTTTA
AAGGGATAGGAAAAAAACGGGCTGAAGCTATTATTGCTTATAGAGAGAATCATCAAGGGTTTAAATCTCTGGAAGAGCTT
GCGGAAGTCAAGGGTATAGGGCAGCGTTTTGTAGATAAAAATAGAGAAAAACTGAAAGAAATTTTCGTTATTAATTAA

Domains


Predicted by InterproScan.

(37-98)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB Q5ZXC2

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Legionella pneumophila str. Paris

100

100

1

  comEA Legionella pneumophila strain ERS1305867

100

100

1

  comE1/comEA Haemophilus influenzae Rd KW20

35.455

100

0.371

  comEA Staphylococcus aureus N315

38.384

94.286

0.362

  comEA Staphylococcus aureus MW2

38.384

94.286

0.362