Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   V6U69_RS04340 Genome accession   NZ_CP145867
Coordinates   966247..967662 (+) Length   471 a.a.
NCBI ID   WP_410534271.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS10     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 961247..972662
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U69_RS04315 (V6U69_04315) - 961698..962270 (-) 573 WP_070438309.1 ECF transporter S component -
  V6U69_RS04320 (V6U69_04320) coaC 962299..962844 (-) 546 WP_073686340.1 phosphopantothenoylcysteine decarboxylase -
  V6U69_RS04325 (V6U69_04325) - 962837..963520 (-) 684 WP_110981460.1 phosphopantothenate--cysteine ligase -
  V6U69_RS04330 (V6U69_04330) - 963714..965384 (+) 1671 WP_410534268.1 formate--tetrahydrofolate ligase -
  V6U69_RS04335 (V6U69_04335) ciaR 965583..966257 (+) 675 WP_410534269.1 response regulator transcription factor Regulator
  V6U69_RS04340 (V6U69_04340) ciaH 966247..967662 (+) 1416 WP_410534271.1 sensor histidine kinase Regulator
  V6U69_RS04345 (V6U69_04345) rpsT 967747..967983 (-) 237 WP_037597891.1 30S ribosomal protein S20 -
  V6U69_RS04350 (V6U69_04350) coaA 968053..968973 (-) 921 WP_037597889.1 type I pantothenate kinase -
  V6U69_RS04355 (V6U69_04355) - 969087..969677 (+) 591 WP_073951006.1 class I SAM-dependent methyltransferase -
  V6U69_RS04360 (V6U69_04360) - 969674..970951 (+) 1278 WP_410534273.1 pyrimidine-nucleoside phosphorylase -
  V6U69_RS04365 (V6U69_04365) deoC 970986..971648 (+) 663 WP_049546060.1 deoxyribose-phosphate aldolase -
  V6U69_RS04370 (V6U69_04370) - 971635..972033 (+) 399 WP_002891126.1 cytidine deaminase -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53479.21 Da        Isoelectric Point: 8.7681

>NTDB_id=940783 V6U69_RS04340 WP_410534271.1 966247..967662(+) (ciaH) [Streptococcus salivarius strain KSS10]
MLTKFFNYLFRRIKSDGFKSFIHFFATFSGIFLVMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDTKGSTDETPDSSGSKKESKKKSKMEDAPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTGQNQVSRPIHTDKTLLKQLMTILFDNAIKYTEDDGHVTFTVRTNERHLYIS
VADNGPGISDSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVLALKGTIVVKDNQPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=940783 V6U69_RS04340 WP_410534271.1 966247..967662(+) (ciaH) [Streptococcus salivarius strain KSS10]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATCAAGTCAGACGGATTTAAGTCGTTCATTCATTTCTTTGCTAC
TTTTTCTGGTATTTTCCTTGTCATGACTGTCATGATTTTGCAGATTCTGAGTTACGGCGTTTATTCCAATGTGGACTCTA
GTCTGAAAATGGCAGCAACTAAGACCAATTCTTATTTAGAAATGGAAATGCTAAAACGGGAACTTTTTCTGACTTCTGAG
GTAGATCAAAATAATACGACAACCATCTACCAAGCCTATGATACTAAAGGGTCGACAGATGAAACACCTGACTCGAGTGG
CTCTAAAAAAGAATCTAAGAAGAAATCAAAGATGGAAGATGCCCCTCACGATTTATCTGTTGCGGCGAATACCAGTGTCT
TAGTGCTTGATAAGAATGGAAAAGTCCTCAATGTCGTTGACAAATTTTCTAGCTTATCCAATTTACCAATAGATAAAAAT
AACATTGATGTTATCAGCAAGGGAAGCGCTCAGAATTATTTCGATCAAACCGAAAAGTATCGCCTGATTACTGAAAAAGT
AGATAATAGTCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCCACTGAACGTT
ATGTCAAGCTCATTGTTATCATGATGAGTTTCTTCTGGCTCCTATCTGTTGCGGCTAGTATGTATTTGGCTAAGTGGTCA
AGACGTCCTATCCAGGAAAGTCTGGAGAAGCAGAAGGCATTTGTTGAAAATGCCAGTCACGAGTTACGGACACCGCTTGC
TGTGATTCAAAACCGATTAGAAGTTCTTTTCCGAAAGCCTGAGAGCACCATTTTAGATAATTCAGAGAATATTGCTTCAA
GTCTTGATGAAGTACGTAATATGCGTCTGTTGACGACAAATCTCTTGAACTTGGCTCGTCGTGACGATGGTATTAAGCCG
GAAATCGAAACCTTAGAACCTGCTTTCTTTGACACAGTATTTACCAATTATGCTATGATTGCTGAAGAAAATGAGAAAGG
TTTCACGGGTCAAAACCAAGTTAGTCGTCCAATCCATACTGATAAAACGCTATTGAAGCAGCTAATGACCATATTATTTG
ATAATGCTATTAAATATACGGAAGATGATGGACATGTTACCTTTACTGTTCGCACTAATGAGCGCCATCTTTATATTTCG
GTAGCTGATAATGGTCCTGGGATATCAGATAGTGATAAGAAAAAAATCTTTGATCGCTTTTATCGCGTAGATAAGGCTAG
AACCAGACAAAAAGGTGGGTTTGGACTGGGCTTATCCCTAGCGCAACAAATTGTTTTAGCTCTTAAAGGAACAATTGTTG
TTAAAGATAATCAACCAAAGGGAACGATTTTTGAAGTTAAAATCACTGGAGTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.522

97.665

0.552
  ciaH Streptococcus pneumoniae Rx1

50

98.514

0.493
  ciaH Streptococcus pneumoniae D39

50

98.514

0.493
  ciaH Streptococcus pneumoniae R6

50

98.514

0.493
  ciaH Streptococcus pneumoniae TIGR4

50

98.514

0.493