Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   V6U68_RS09385 Genome accession   NZ_CP145866
Coordinates   2012996..2013952 (-) Length   318 a.a.
NCBI ID   WP_037601477.1    Uniprot ID   A0A074IXP5
Organism   Streptococcus salivarius strain KSS9     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2007996..2018952
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U68_RS09355 (V6U68_09335) proC 2008534..2009304 (+) 771 WP_410531676.1 pyrroline-5-carboxylate reductase -
  V6U68_RS09360 (V6U68_09340) - 2009331..2009993 (-) 663 WP_013991258.1 CPBP family intramembrane glutamic endopeptidase -
  V6U68_RS09365 (V6U68_09345) - 2010106..2010552 (-) 447 WP_013991259.1 hypothetical protein -
  V6U68_RS09370 (V6U68_09350) - 2010630..2011286 (-) 657 WP_037601483.1 CPBP family intramembrane glutamic endopeptidase -
  V6U68_RS09375 (V6U68_09355) - 2011298..2011495 (-) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  V6U68_RS09380 (V6U68_09360) - 2011746..2012939 (-) 1194 WP_003095894.1 acetate kinase -
  V6U68_RS09385 (V6U68_09365) comYH 2012996..2013952 (-) 957 WP_037601477.1 class I SAM-dependent methyltransferase Machinery gene
  V6U68_RS09390 (V6U68_09370) comGG 2013997..2014314 (-) 318 WP_041817287.1 competence type IV pilus minor pilin ComGG -
  V6U68_RS09395 (V6U68_09375) comYF 2014292..2014729 (-) 438 WP_080611747.1 competence type IV pilus minor pilin ComGF Machinery gene
  V6U68_RS09400 (V6U68_09380) comGE 2014716..2015006 (-) 291 WP_195435963.1 competence type IV pilus minor pilin ComGE -
  V6U68_RS09405 (V6U68_09385) comYD 2014978..2015406 (-) 429 WP_267472584.1 competence type IV pilus minor pilin ComGD Machinery gene
  V6U68_RS09410 (V6U68_09390) comYC 2015366..2015692 (-) 327 WP_002885815.1 competence type IV pilus major pilin ComGC Machinery gene
  V6U68_RS09415 (V6U68_09395) comYB 2015689..2016789 (-) 1101 WP_410531677.1 competence type IV pilus assembly protein ComGB Machinery gene
  V6U68_RS09420 (V6U68_09400) comYA 2016671..2017612 (-) 942 WP_201041167.1 competence type IV pilus ATPase ComGA Machinery gene
  V6U68_RS09425 (V6U68_09405) - 2017692..2018054 (-) 363 WP_073949471.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 318 a.a.        Molecular weight: 35775.66 Da        Isoelectric Point: 4.3440

>NTDB_id=940743 V6U68_RS09385 WP_037601477.1 2012996..2013952(-) (comYH) [Streptococcus salivarius strain KSS9]
MNFEAIETAFELLLENVQTIENDLGTHAYDALIEQNSYYLGAEVANEVIIKNNEKLRALDLSKEEWRRAFQFLFIKLGQL
EALQANHQFTPDAIGFIILYLLEGLTKDDQLDILEIGSGTGNLAETLLNNSQKTLNYMGMEVDDLLIDLSASIADVVNSS
AVYIQEDAVRPHILKESDVIISDLPVGYYPNDEIASRFKVAATGEHTYAHHLLMEQSLKYLKKDGIAILLAPTNLLTSPQ
SDLLKKWLSGYADIIAVITLPEAAFGNKHNMKSIFVLKKQTENAPETFVYPLSDLQNPEILKDFTDNFQKWKSDNSIF

Nucleotide


Download         Length: 957 bp        

>NTDB_id=940743 V6U68_RS09385 WP_037601477.1 2012996..2013952(-) (comYH) [Streptococcus salivarius strain KSS9]
ATGAATTTTGAAGCAATTGAGACAGCTTTTGAGCTGTTGTTAGAAAATGTCCAAACCATTGAAAATGATCTTGGAACCCA
TGCTTACGATGCACTTATTGAGCAAAATTCCTATTATTTGGGGGCTGAGGTAGCTAATGAAGTCATCATCAAAAACAACG
AGAAATTACGTGCTCTTGATCTAAGTAAAGAGGAGTGGCGTCGTGCTTTTCAGTTCTTGTTTATCAAACTAGGGCAATTG
GAAGCTTTACAAGCCAATCACCAATTTACACCAGATGCTATTGGATTTATCATTCTTTACCTACTCGAAGGTTTGACCAA
GGACGACCAATTAGATATTTTGGAGATTGGTTCAGGGACAGGAAACTTGGCTGAAACTCTTCTAAATAATAGTCAGAAAA
CCCTTAATTATATGGGAATGGAAGTTGACGATCTCCTTATCGATTTGTCAGCTAGTATTGCTGATGTGGTGAATTCAAGT
GCAGTTTACATCCAAGAAGATGCTGTTCGACCACACATTCTCAAAGAGAGTGATGTTATTATCAGTGACCTACCTGTTGG
GTATTACCCAAATGATGAGATTGCGAGTCGTTTCAAGGTTGCAGCAACTGGTGAACACACCTATGCCCATCACCTTCTCA
TGGAGCAATCACTCAAGTACCTGAAGAAAGATGGTATTGCTATTCTTTTGGCACCAACTAATCTTTTGACAAGCCCACAA
AGTGACTTGCTTAAGAAATGGCTATCAGGATATGCTGATATTATTGCCGTTATCACTCTTCCAGAAGCAGCTTTTGGCAA
TAAACATAATATGAAGTCTATCTTCGTACTTAAAAAACAAACTGAAAATGCTCCAGAGACCTTCGTTTATCCACTTAGCG
ATTTGCAAAACCCAGAGATCCTCAAGGATTTTACAGATAATTTCCAAAAATGGAAATCAGATAATTCCATTTTCTAG

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A074IXP5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

70.159

99.057

0.695
  comYH Streptococcus mutans UA140

70.159

99.057

0.695