Detailed information NTG0940744

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: V6U68_RS09395
• Genome accession: NZ_CP145866
• Coordinates: 2014292..2014729 (-)
• Length: 145 a.a.
• NCBI ID: WP_080611747.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS9
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2009292..2019729

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U68_RS09360 (V6U68_09340)	-	2009331..2009993 (-)	663	WP_013991258.1	CPBP family intramembrane glutamic endopeptidase	-
V6U68_RS09365 (V6U68_09345)	-	2010106..2010552 (-)	447	WP_013991259.1	hypothetical protein	-
V6U68_RS09370 (V6U68_09350)	-	2010630..2011286 (-)	657	WP_037601483.1	CPBP family intramembrane glutamic endopeptidase	-
V6U68_RS09375 (V6U68_09355)	-	2011298..2011495 (-)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
V6U68_RS09380 (V6U68_09360)	-	2011746..2012939 (-)	1194	WP_003095894.1	acetate kinase	-
V6U68_RS09385 (V6U68_09365)	comYH	2012996..2013952 (-)	957	WP_037601477.1	class I SAM-dependent methyltransferase	Machinery gene
V6U68_RS09390 (V6U68_09370)	comGG	2013997..2014314 (-)	318	WP_041817287.1	competence type IV pilus minor pilin ComGG	-
V6U68_RS09395 (V6U68_09375)	comYF	2014292..2014729 (-)	438	WP_080611747.1	competence type IV pilus minor pilin ComGF	Machinery gene
V6U68_RS09400 (V6U68_09380)	comGE	2014716..2015006 (-)	291	WP_195435963.1	competence type IV pilus minor pilin ComGE	-
V6U68_RS09405 (V6U68_09385)	comYD	2014978..2015406 (-)	429	WP_267472584.1	competence type IV pilus minor pilin ComGD	Machinery gene
V6U68_RS09410 (V6U68_09390)	comYC	2015366..2015692 (-)	327	WP_002885815.1	competence type IV pilus major pilin ComGC	Machinery gene
V6U68_RS09415 (V6U68_09395)	comYB	2015689..2016789 (-)	1101	WP_410531677.1	competence type IV pilus assembly protein ComGB	Machinery gene
V6U68_RS09420 (V6U68_09400)	comYA	2016671..2017612 (-)	942	WP_201041167.1	competence type IV pilus ATPase ComGA	Machinery gene
V6U68_RS09425 (V6U68_09405)	-	2017692..2018054 (-)	363	WP_073949471.1	DUF1033 family protein	-
V6U68_RS09430 (V6U68_09410)	-	2018266..2019515 (+)	1250	Protein_1801	ISL3 family transposase	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16212.63 Da
• Isoelectric Point: 8.4658

>NTDB_id=940744 V6U68_RS09395 WP_080611747.1 2014292..2014729(-) (comYF) [Streptococcus salivarius strain KSS9]
MSLNSKVRAFTLLECLVALLVIAGSIQVYQGLTTVLVSNVKQVKQQENQDWLLFVQQMEAELEGCQLVKVEGNKLYVKQD
NQDLAFGLSSATDFRKTNADGRGYQPMLFNVKSSTISQNNQIVTIQVTLKNGLQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=940744 V6U68_RS09395 WP_080611747.1 2014292..2014729(-) (comYF) [Streptococcus salivarius strain KSS9]
ATGTCTCTAAATAGTAAGGTTCGCGCCTTTACCCTCTTGGAATGTCTAGTAGCCTTGTTGGTGATTGCTGGTTCAATTCA
AGTTTATCAAGGTCTGACCACAGTATTGGTGAGCAATGTTAAGCAGGTCAAGCAACAAGAAAACCAAGACTGGCTTTTAT
TTGTTCAACAAATGGAGGCAGAGTTAGAAGGCTGTCAGTTGGTAAAGGTAGAAGGGAACAAGCTCTATGTCAAGCAGGAT
AATCAAGACCTGGCTTTTGGCCTTTCAAGTGCTACTGATTTTCGAAAAACAAATGCTGACGGTCGAGGCTACCAACCAAT
GCTTTTCAATGTAAAATCTAGTACGATTAGTCAAAATAACCAGATAGTCACCATCCAAGTGACTCTTAAAAATGGGCTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	56.738	97.241	0.552
comYF	Streptococcus mutans UA159	56.028	97.241	0.545
comGF/cglF	Streptococcus pneumoniae Rx1	50.704	97.931	0.497
comGF/cglF	Streptococcus pneumoniae D39	50.704	97.931	0.497
comGF/cglF	Streptococcus pneumoniae R6	50.704	97.931	0.497
comGF/cglF	Streptococcus pneumoniae TIGR4	50.704	97.931	0.497
comGF/cglF	Streptococcus mitis NCTC 12261	47.917	99.31	0.476
comGF/cglF	Streptococcus mitis SK321	47.917	99.31	0.476
comGF	Lactococcus lactis subsp. cremoris KW2	44.604	95.862	0.428