Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   V6U68_RS05870 Genome accession   NZ_CP145866
Coordinates   1206373..1207788 (-) Length   471 a.a.
NCBI ID   WP_410531379.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS9     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1201373..1212788
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U68_RS05840 (V6U68_05830) - 1202004..1202402 (-) 399 WP_410531377.1 cytidine deaminase -
  V6U68_RS05845 (V6U68_05835) deoC 1202389..1203051 (-) 663 WP_410531378.1 deoxyribose-phosphate aldolase -
  V6U68_RS05850 (V6U68_05840) - 1203085..1204362 (-) 1278 WP_013990469.1 pyrimidine-nucleoside phosphorylase -
  V6U68_RS05855 (V6U68_05845) - 1204359..1204949 (-) 591 WP_013990468.1 class I SAM-dependent methyltransferase -
  V6U68_RS05860 (V6U68_05850) coaA 1205062..1205982 (+) 921 WP_013990467.1 type I pantothenate kinase -
  V6U68_RS05865 (V6U68_05855) rpsT 1206052..1206288 (+) 237 WP_004182129.1 30S ribosomal protein S20 -
  V6U68_RS05870 (V6U68_05860) ciaH 1206373..1207788 (-) 1416 WP_410531379.1 sensor histidine kinase Regulator
  V6U68_RS05875 (V6U68_05865) ciaR 1207778..1208452 (-) 675 WP_049546057.1 response regulator transcription factor Regulator
  V6U68_RS05880 (V6U68_05870) - 1208651..1210321 (-) 1671 WP_013990464.1 formate--tetrahydrofolate ligase -
  V6U68_RS05885 (V6U68_05875) - 1210516..1211199 (+) 684 WP_013990463.1 phosphopantothenate--cysteine ligase -
  V6U68_RS05890 (V6U68_05880) coaC 1211192..1211737 (+) 546 WP_013990462.1 phosphopantothenoylcysteine decarboxylase -
  V6U68_RS05895 (V6U68_05885) - 1211766..1212338 (+) 573 WP_022496698.1 ECF transporter S component -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53470.25 Da        Isoelectric Point: 8.7702

>NTDB_id=940720 V6U68_RS05870 WP_410531379.1 1206373..1207788(-) (ciaH) [Streptococcus salivarius strain KSS9]
MLTKFFNYLFRRIKSEGFKSFIHFFATFSGIFLVMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDTKGSADETPDSSGSKKESKKKSKMEDAPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTGQNQVSRPIHTDKTLLKQLMTILFDNAIKYTEDDGHVIFTVRTNDRHLYIS
VADNGPGISDSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVLALKGTIVVKDNHPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=940720 V6U68_RS05870 WP_410531379.1 1206373..1207788(-) (ciaH) [Streptococcus salivarius strain KSS9]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATCAAGTCAGAAGGATTTAAGTCTTTCATTCATTTCTTTGCTAC
TTTTTCTGGTATTTTCCTTGTCATGACTGTCATGATTTTGCAGATTCTGAGTTACGGCGTTTATTCCAATGTGGACTCTA
GTCTGAAAATGGCAGCAACTAAGACCAATTCTTATTTAGAAATGGAAATGCTAAAACGGGAACTTTTTCTGACTTCTGAG
GTAGATCAAAATAATACGACAACCATTTACCAAGCCTATGATACTAAAGGGTCGGCAGATGAAACACCTGACTCGAGTGG
CTCTAAAAAAGAATCTAAGAAGAAATCAAAGATGGAAGATGCCCCTCACGATTTATCTGTTGCGGCGAATACCAGTGTCT
TAGTGCTTGATAAGAATGGAAAAGTTCTCAATGTCGTTGACAAATTTTCTAGCTTATCCAATTTACCAATAGATAAAAAT
AACATTGATGTTATCAGTAAGGGAAGCGCTCAGAATTATTTCGATCAAACCGAAAAGTATCGCCTGATTACTGAAAAAGT
AGATAATAGTCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCCACTGAACGTT
ATGTCAAGCTCATTGTCATCATGATGAGTTTCTTCTGGCTCCTATCTGTTGCGGCTAGTATGTATTTGGCCAAGTGGTCA
AGACGTCCTATCCAGGAAAGTCTGGAGAAGCAGAAGGCATTTGTTGAAAATGCCAGTCACGAGTTACGGACACCGCTTGC
TGTGATTCAAAACCGATTAGAAGTTCTTTTCCGCAAGCCTGAGAGCACCATTTTAGATAATTCAGAGAATATTGCTTCAA
GTCTTGATGAAGTACGTAATATGCGTCTGTTGACGACAAATCTCTTGAACTTGGCTCGTCGTGACGATGGTATTAAGCCG
GAAATCGAAACCTTAGAACCTGCTTTCTTTGATACAGTATTTACCAATTATGCTATGATTGCTGAAGAAAATGAGAAAGG
TTTCACGGGTCAAAACCAAGTTAGTCGTCCAATCCATACTGATAAAACGCTATTGAAGCAGCTAATGACCATATTATTTG
ATAATGCTATTAAATATACGGAAGATGATGGACATGTTATCTTTACTGTTCGCACTAATGACCGCCATCTTTATATTTCG
GTAGCTGATAATGGTCCTGGGATATCAGATAGTGATAAGAAAAAAATCTTTGATCGCTTTTATCGCGTAGATAAGGCTAG
AACCAGACAAAAAGGTGGGTTTGGACTGGGCTTATCCCTAGCGCAACAAATTGTTTTAGCTCTTAAAGGAACAATTGTTG
TCAAGGACAATCATCCGAAGGGGACTATTTTTGAAGTTAAAATCACTGGAGTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.304

97.665

0.55
  ciaH Streptococcus pneumoniae Rx1

49.784

98.514

0.49
  ciaH Streptococcus pneumoniae D39

49.784

98.514

0.49
  ciaH Streptococcus pneumoniae R6

49.784

98.514

0.49
  ciaH Streptococcus pneumoniae TIGR4

49.784

98.514

0.49