Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   V6U66_RS04580 Genome accession   NZ_CP145864
Coordinates   1023667..1025082 (+) Length   471 a.a.
NCBI ID   WP_037604990.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS7     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1018667..1030082
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U66_RS04555 (V6U66_04540) - 1019118..1019690 (-) 573 WP_084871334.1 ECF transporter S component -
  V6U66_RS04560 (V6U66_04545) coaC 1019719..1020264 (-) 546 WP_084871335.1 phosphopantothenoylcysteine decarboxylase -
  V6U66_RS04565 (V6U66_04550) - 1020257..1020940 (-) 684 WP_084871336.1 phosphopantothenate--cysteine ligase -
  V6U66_RS04570 (V6U66_04555) - 1021134..1022804 (+) 1671 WP_048675542.1 formate--tetrahydrofolate ligase -
  V6U66_RS04575 (V6U66_04560) ciaR 1023003..1023677 (+) 675 WP_004182019.1 response regulator transcription factor Regulator
  V6U66_RS04580 (V6U66_04565) ciaH 1023667..1025082 (+) 1416 WP_037604990.1 sensor histidine kinase Regulator
  V6U66_RS04585 (V6U66_04570) rpsT 1025166..1025402 (-) 237 WP_004182129.1 30S ribosomal protein S20 -
  V6U66_RS04590 (V6U66_04575) coaA 1025472..1026392 (-) 921 WP_004182102.1 type I pantothenate kinase -
  V6U66_RS04595 (V6U66_04580) - 1026505..1027095 (+) 591 WP_155213883.1 class I SAM-dependent methyltransferase -
  V6U66_RS04600 (V6U66_04585) - 1027092..1028369 (+) 1278 WP_155213884.1 pyrimidine-nucleoside phosphorylase -
  V6U66_RS04605 (V6U66_04590) deoC 1028403..1029065 (+) 663 WP_155213885.1 deoxyribose-phosphate aldolase -
  V6U66_RS04610 (V6U66_04595) - 1029052..1029449 (+) 398 Protein_852 cytidine deaminase -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53495.27 Da        Isoelectric Point: 8.7640

>NTDB_id=940580 V6U66_RS04580 WP_037604990.1 1023667..1025082(+) (ciaH) [Streptococcus salivarius strain KSS7]
MLTKFFNYLFRRIKSDGFKSFIHFFATFSGIFLIMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDTKESTAETPDSSGSKKEPKKKSKIEDAPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTAQNQVSRPIQTDKTLLKQLMTILFDNAIKYTEDDGHVTFTVRTNDRQLYIS
VADNGPGISDSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVLALKGTIVVKDNQPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=940580 V6U66_RS04580 WP_037604990.1 1023667..1025082(+) (ciaH) [Streptococcus salivarius strain KSS7]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATCAAGTCAGACGGATTTAAGTCGTTCATTCATTTTTTTGCTAC
TTTTTCTGGTATTTTCCTTATCATGACTGTCATGATTTTACAGATTTTGAGTTACGGCGTTTATTCCAATGTGGATTCTA
GTCTGAAAATGGCAGCGACTAAGACCAATTCTTATTTAGAAATGGAAATGCTAAAACGGGAACTTTTTCTGACTTCTGAG
GTGGATCAAAATAATACGACAACCATTTACCAAGCCTATGATACTAAAGAGTCAACAGCTGAAACACCTGACTCGAGTGG
CTCTAAAAAAGAACCTAAGAAGAAATCAAAAATTGAAGATGCCCCTCACGATTTATCAGTTGCGGCAAATACCAGTGTCT
TGGTACTTGATAAGAATGGGAAAGTCCTCAATGTCGTTGATAAATTTTCAAGTTTATCTAATTTACCAATAGATAAAAAT
AACATTGATGTTATCAGCAAGGGAAGTGCTCAGAATTATTTCGATCAAACAGAAAAGTATCGTCTGATTACTGAAAAAGT
AGATAATAGTCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCTACTGAACGTT
ATGTTAAGCTCATTGTCATCATGATGAGTTTCTTCTGGCTCTTATCTGTTGCGGCTAGTATGTATTTGGCTAAGTGGTCA
AGACGTCCTATCCAGGAAAGCTTGGAGAAGCAGAAGGCTTTTGTTGAAAATGCTAGTCATGAGTTACGGACACCACTTGC
TGTGATTCAAAACAGATTAGAAGTTCTTTTCCGCAAGCCTGAGAGCACCATTCTAGATAATTCAGAGAATATTGCATCAA
GTCTTGATGAAGTACGTAATATGCGTCTTTTGACGACTAATCTCTTGAACTTGGCTCGTCGTGACGATGGTATTAAACCA
GAAATCGAAACCTTAGAACCTGCTTTCTTTGATACAGTCTTTACCAATTATGCCATGATTGCAGAAGAAAATGAGAAAGG
TTTCACGGCTCAAAACCAAGTTAGTCGTCCAATCCAAACTGATAAAACGCTATTGAAACAGTTAATGACCATCTTATTTG
ATAATGCTATTAAATATACGGAAGATGATGGACATGTTACCTTTACTGTTCGCACTAATGACCGCCAACTTTATATTTCT
GTAGCTGATAATGGTCCTGGGATATCAGATAGTGATAAGAAAAAAATCTTTGATCGATTTTATCGCGTAGATAAGGCTAG
AACCAGACAAAAAGGTGGGTTTGGACTTGGCTTATCCCTAGCGCAACAAATTGTTTTAGCCCTAAAAGGAACAATTGTTG
TTAAAGATAATCAACCAAAGGGAACGATTTTTGAAGTTAAGATCACTGGAGTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.739

97.665

0.554
  ciaH Streptococcus pneumoniae Rx1

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae D39

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae R6

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae TIGR4

50.216

98.514

0.495