Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   V6U64_RS08620 Genome accession   NZ_CP145862
Coordinates   1879326..1880015 (-) Length   229 a.a.
NCBI ID   WP_002883757.1    Uniprot ID   A0AB33ZE44
Organism   Streptococcus salivarius strain KSS4     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1874326..1885015
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U64_RS08600 (V6U64_08600) dnaI 1875121..1876023 (-) 903 WP_014633898.1 primosomal protein DnaI -
  V6U64_RS08605 (V6U64_08605) - 1876027..1877202 (-) 1176 WP_037610617.1 DnaD domain protein -
  V6U64_RS08610 (V6U64_08610) nrdR 1877199..1877678 (-) 480 WP_002883820.1 transcriptional regulator NrdR -
  V6U64_RS08615 (V6U64_08615) covS 1877800..1879329 (-) 1530 WP_014633896.1 HAMP domain-containing histidine kinase Regulator
  V6U64_RS08620 (V6U64_08620) covR 1879326..1880015 (-) 690 WP_002883757.1 response regulator transcription factor Regulator
  V6U64_RS08625 (V6U64_08625) - 1880171..1880707 (-) 537 WP_037600313.1 DUF177 domain-containing protein -
  V6U64_RS08630 (V6U64_08630) rsmG 1881006..1881719 (+) 714 WP_037600311.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  V6U64_RS08635 (V6U64_08635) - 1881788..1883152 (+) 1365 WP_410536539.1 TrkH family potassium uptake protein -
  V6U64_RS08640 (V6U64_08640) - 1883192..1883863 (+) 672 WP_155214076.1 potassium channel family protein -
  V6U64_RS08645 (V6U64_08645) - 1883953..1884783 (-) 831 WP_021143559.1 energy-coupling factor transporter transmembrane component T family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26501.51 Da        Isoelectric Point: 4.6354

>NTDB_id=940467 V6U64_RS08620 WP_002883757.1 1879326..1880015(-) (covR) [Streptococcus salivarius strain KSS4]
MSKRILIVEDEKNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARIRATFRRQDIEAAKNAPAKASTYRDLKLDVQNRTVVRGDEAIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDAIETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=940467 V6U64_RS08620 WP_002883757.1 1879326..1880015(-) (covR) [Streptococcus salivarius strain KSS4]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAAAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCAGACAACGGACGCGAAGGACTTGAAATGGCACTCGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTTGAAGTAACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGTGATTCAATCATGGACATTGTTGCTGGTTTGGACCGCGGTGCTGATGACTATATTGTAAAACCATTTGCGATTGA
AGAATTGTTGGCACGTATCCGTGCAACCTTCCGTCGCCAAGATATCGAAGCTGCTAAGAATGCACCAGCAAAAGCATCAA
CTTATCGTGATTTGAAATTGGATGTTCAAAACCGTACAGTTGTTCGTGGTGATGAAGCAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTGAGCAATATGAACCAAGTGATGACCCGTGAGGAACTCTTGCTTCAAGTTTGGAAATA
TGATGACGCCATCGAAACAAACGTGGTAGATGTTTATATTCGTTACTTGCGTGGAAAAATCGATGTTCCAGGTAAGGAAT
CATATATTCAAACAGTACGAGGAATGGGTTACGTTATCCGTGAAAAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

100

100

1
  covR Lactococcus lactis subsp. lactis strain DGCC12653

68.421

99.563

0.681
  vicR Streptococcus mutans UA159

45.923

100

0.467
  micA Streptococcus pneumoniae Cp1015

44.156

100

0.445