Detailed information NTG0940391

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: V6U63_RS07635
• Genome accession: NZ_CP145861
• Coordinates: 1687959..1690199 (-)
• Length: 746 a.a.
• NCBI ID: WP_349955294.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS3
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1682959..1695199

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U63_RS07615 (V6U63_07610)	-	1683822..1684682 (-)	861	WP_002884335.1	methionyl aminopeptidase	-
V6U63_RS07620 (V6U63_07615)	spxR	1684727..1686007 (-)	1281	WP_002884454.1	CBS-HotDog domain-containing transcription factor SpxR	-
V6U63_RS07625 (V6U63_07620)	-	1686000..1686545 (-)	546	WP_013991031.1	GNAT family N-acetyltransferase	-
V6U63_RS07630 (V6U63_07625)	-	1686611..1687873 (-)	1263	WP_084915391.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
V6U63_RS07635 (V6U63_07630)	comEC/celB	1687959..1690199 (-)	2241	WP_349955294.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
V6U63_RS07640 (V6U63_07635)	comEA	1690189..1690884 (-)	696	WP_022496133.1	helix-hairpin-helix domain-containing protein	Machinery gene
V6U63_RS07645 (V6U63_07640)	-	1690993..1691748 (-)	756	WP_022496132.1	lysophospholipid acyltransferase family protein	-
V6U63_RS07650 (V6U63_07645)	-	1691878..1692813 (+)	936	WP_022496131.1	polysaccharide deacetylase family protein	-
V6U63_RS07655 (V6U63_07650)	-	1692863..1693627 (+)	765	WP_349955293.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
V6U63_RS07660 (V6U63_07655)	-	1693631..1693900 (+)	270	WP_022496129.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84435.27 Da
• Isoelectric Point: 9.9046

>NTDB_id=940391 V6U63_RS07635 WP_349955294.1 1687959..1690199(-) (comEC/celB) [Streptococcus salivarius strain KSS3]
MWLKKAPINLFSLALLIAALYFTIFNTNVYATGVLSFLLGCFLKHHWKNKVALKLVGLVGSFFLVYFLFLHHRATIQDKQ
APTEINQVTLVADTLSVNGEQLSAIGKAKGQTYQVFYRLKSEKEQHFFKTTSQTLVLKGKIKLSLAIGQRNFQGFNYQSY
LASQGIYRMAQIERLDHVVPQKSLSPLAFFHQLRRRALVHIQTHFPNPMRHYMTGLLFGYLGKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKDYLFIILLPFSLCYGLMTGWTASVLRSLIQSLLAEFGIKKLDNMGITLLLLFLF
LPHFLLTVGGVLSCSYAFLLCLFDFEEMSSLKKSICTSLVLSLGILPFLTFYYGTFQPVSLILTAMFSIVFDSFLLPVLT
VFFALSGLVIFSQINPLFEWMEAFLTWIQSWIGQPLILGKPSLFQFGLMIAVLVMLFDFWKKPQFRICLLMIFGLLMVWV
KHPLTNEVTMVDVGQGDSIFLRSMKGDTILIDVGGKVTFGSKEKWQEASQTSNAEKTLIPYLQARGVSQIDHLVLTHTDT
DHIGDLEEVAKRFKIKEICVSQGALTKPSFVKRLRTLKRPVRTLKAGDNLPMMGSKLQVLYPNKVGDGGNNDSIVLYGKL
LGSSFLFTGDLEKEGEEELMVSYPNLKASVLKAGHHGSKGSSSEAFLDQLQPSLALVSAGENNRYKHPNDETLERFKERH
IKVLRTDQNGAIRFKGWFKWSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=940391 V6U63_RS07635 WP_349955294.1 1687959..1690199(-) (comEC/celB) [Streptococcus salivarius strain KSS3]
ATGTGGCTTAAAAAAGCTCCAATCAATCTTTTTTCCTTGGCTCTGTTAATAGCTGCCCTTTATTTTACGATTTTTAACAC
AAATGTTTATGCTACTGGGGTTTTGTCTTTTCTTTTAGGATGTTTTTTGAAGCATCATTGGAAGAATAAGGTAGCCCTAA
AGTTGGTGGGACTTGTAGGTAGTTTCTTTTTGGTCTACTTTTTATTCTTGCACCACAGAGCTACCATACAAGATAAACAA
GCTCCTACTGAAATCAATCAGGTGACTCTGGTTGCTGATACGCTGTCGGTTAATGGTGAGCAATTATCAGCTATTGGAAA
GGCAAAGGGACAAACTTATCAGGTCTTTTACCGACTCAAATCTGAGAAGGAGCAGCATTTTTTTAAGACTACTAGCCAAA
CGTTGGTATTAAAAGGGAAAATAAAGTTATCCCTAGCAATTGGTCAACGTAATTTTCAAGGGTTTAATTATCAGTCTTAT
CTAGCCAGTCAAGGCATTTATCGAATGGCTCAGATTGAACGCTTGGACCATGTGGTGCCTCAAAAATCTCTATCTCCCCT
AGCTTTTTTCCATCAACTGAGGAGGAGGGCATTGGTTCATATCCAGACGCACTTTCCTAATCCTATGAGACACTATATGA
CAGGTCTGCTCTTTGGGTATTTGGGTAAGGAGTTTGATGAGCAAAGTCAGCTTTACACAAGCTTAGGTATTATTCATCTA
TTCGCACTTTCGGGGATGCAAGTGGGATTTTTTCTGGGATGGTTTCGCTATGGACTCCTACGCTTGGGCCTTCCTAAAGA
TTATCTATTTATTATCTTGCTGCCTTTTTCCTTGTGTTATGGCTTAATGACAGGTTGGACAGCTTCAGTCCTACGTTCCC
TGATTCAAAGTTTGTTAGCGGAGTTTGGTATTAAAAAACTGGATAATATGGGGATAACTTTGCTTCTATTGTTTCTCTTT
TTACCTCATTTTCTTTTGACAGTGGGAGGTGTTTTAAGTTGTTCCTATGCCTTTTTGTTGTGTTTGTTTGATTTTGAGGA
GATGTCATCTCTTAAAAAGTCAATCTGTACGAGCTTAGTGTTGAGTCTTGGGATTTTGCCTTTTCTAACTTTCTATTATG
GGACCTTTCAACCGGTGAGTTTAATTCTGACGGCGATGTTTTCGATAGTATTTGATAGCTTTCTCTTGCCTGTATTGACA
GTCTTCTTTGCTCTTTCAGGACTGGTAATCTTTTCTCAAATCAACCCACTTTTTGAATGGATGGAGGCCTTTTTGACTTG
GATACAATCCTGGATAGGCCAGCCTTTGATTTTAGGGAAACCTAGTTTGTTTCAGTTTGGCTTGATGATAGCTGTCTTGG
TTATGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGGATTTGCCTTTTGATGATTTTTGGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAACCAATGAGGTGACTATGGTTGACGTTGGTCAGGGAGATAGTATTTTTCTGAGGAGTATGAAAGGCGA
TACCATCCTAATTGATGTGGGTGGCAAGGTGACTTTCGGGTCAAAGGAAAAATGGCAAGAGGCTAGCCAGACGAGCAATG
CGGAGAAAACCTTGATTCCCTACCTACAGGCTAGGGGAGTGTCTCAAATTGACCATCTGGTCCTGACTCATACGGATACA
GACCATATTGGTGATTTGGAAGAAGTAGCCAAGCGGTTTAAGATTAAGGAAATCTGTGTCAGTCAAGGAGCTTTGACTAA
GCCTAGTTTTGTGAAACGACTTCGAACTTTAAAACGCCCAGTTCGCACTCTAAAGGCTGGAGACAACTTACCCATGATGG
GAAGTAAGCTACAGGTTCTTTATCCAAATAAAGTTGGTGATGGTGGTAACAACGATTCGATAGTTCTTTACGGAAAACTA
TTAGGAAGTAGTTTTTTGTTTACGGGTGATCTAGAAAAAGAAGGAGAGGAGGAACTGATGGTCAGCTATCCTAATTTAAA
GGCTAGTGTCCTCAAAGCCGGACACCACGGTTCAAAAGGGTCATCGTCTGAAGCGTTTTTGGACCAGTTGCAGCCCTCCC
TTGCCCTTGTTTCAGCTGGTGAGAATAATCGTTATAAACATCCAAATGATGAAACTTTGGAGCGTTTCAAGGAACGTCAC
ATTAAGGTTTTACGAACAGACCAGAACGGTGCTATCCGTTTTAAGGGGTGGTTTAAGTGGTCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-462)

• Domain of unknown function (DUF4131) (DUF4131) (29-169)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-699)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	48.594	100	0.487
comEC/celB	Streptococcus mitis SK321	48.262	100	0.484
comEC/celB	Streptococcus pneumoniae Rx1	47.193	100	0.473
comEC/celB	Streptococcus pneumoniae D39	47.193	100	0.473
comEC/celB	Streptococcus pneumoniae R6	47.193	100	0.473
comEC/celB	Streptococcus pneumoniae TIGR4	47.059	100	0.472
comEC	Lactococcus lactis subsp. cremoris KW2	43.514	99.196	0.432