Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   V6U62_RS04365 Genome accession   NZ_CP145860
Coordinates   972366..973781 (+) Length   471 a.a.
NCBI ID   WP_037600837.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS2     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 967366..978781
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U62_RS04340 (V6U62_04330) - 967816..968388 (-) 573 WP_022496698.1 ECF transporter S component -
  V6U62_RS04345 (V6U62_04335) coaC 968417..968962 (-) 546 WP_022496697.1 phosphopantothenoylcysteine decarboxylase -
  V6U62_RS04350 (V6U62_04340) - 968955..969638 (-) 684 WP_022496696.1 phosphopantothenate--cysteine ligase -
  V6U62_RS04355 (V6U62_04345) - 969833..971503 (+) 1671 WP_004182072.1 formate--tetrahydrofolate ligase -
  V6U62_RS04360 (V6U62_04350) ciaR 971702..972376 (+) 675 WP_002891134.1 response regulator transcription factor Regulator
  V6U62_RS04365 (V6U62_04355) ciaH 972366..973781 (+) 1416 WP_037600837.1 sensor histidine kinase Regulator
  V6U62_RS04370 (V6U62_04360) rpsT 973859..974095 (-) 237 WP_004182129.1 30S ribosomal protein S20 -
  V6U62_RS04375 (V6U62_04365) coaA 974165..975085 (-) 921 WP_022496694.1 type I pantothenate kinase -
  V6U62_RS04380 (V6U62_04370) - 975198..975788 (+) 591 WP_014633038.1 class I SAM-dependent methyltransferase -
  V6U62_RS04385 (V6U62_04375) - 975785..977062 (+) 1278 WP_022496693.1 pyrimidine-nucleoside phosphorylase -
  V6U62_RS04390 (V6U62_04380) deoC 977096..977758 (+) 663 WP_022496692.1 deoxyribose-phosphate aldolase -
  V6U62_RS04395 (V6U62_04385) - 977745..978143 (+) 399 WP_037600840.1 cytidine deaminase -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53520.35 Da        Isoelectric Point: 8.5216

>NTDB_id=940312 V6U62_RS04365 WP_037600837.1 972366..973781(+) (ciaH) [Streptococcus salivarius strain KSS2]
MLTKFFNYLFRRIKSDGFKSFIHFFATFSGIFLIMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDTKESTAETPDSSGSKKEPKKKSKIEDTPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTAQNQVGRPIQTDKTLLKQLMTILFDNAIKYTEDDGHVTFTVRTNDRHLYIC
VADNGPGISDSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVLALKGTIVVKDNQPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=940312 V6U62_RS04365 WP_037600837.1 972366..973781(+) (ciaH) [Streptococcus salivarius strain KSS2]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATTAAGTCAGACGGATTTAAGTCGTTCATTCATTTCTTTGCCAC
TTTTTCTGGCATTTTCCTTATCATGACTGTCATGATTTTGCAGATTCTGAGTTACGGTGTTTATTCCAATGTGGACTCTA
GTCTGAAAATGGCAGCAACTAAGACCAATTCTTATTTAGAAATGGAAATGCTCAAACGGGAACTTTTTCTGACTTCTGAG
GTAGATCAAAATAATACGACAACCATTTACCAAGCCTATGATACTAAAGAGTCGACAGCTGAAACACCTGACTCGAGTGG
CTCTAAAAAAGAACCTAAGAAGAAATCAAAAATTGAAGATACCCCTCACGATTTATCTGTTGCGGCAAATACTAGTGTCT
TGGTACTTGATAAGAATGGAAAAGTCCTTAATGTTGTTGATAAATTTTCAAGCTTATCCAATTTACCAATAGACAAAAAT
AACATTGATGTTATCAGCAAGGGAAGTGCTCAGAATTATTTCGATCAAACGGAAAAGTACCGTCTGATTACTGAAAAAGT
AGACAATAGTCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCTACTGAACGTT
ATGTTAAGCTCATTGTCATCATGATGAGTTTCTTCTGGCTCTTATCTGTTGCGGCTAGTATGTATTTGGCCAAGTGGTCA
AGACGTCCTATCCAGGAAAGCTTGGAGAAGCAGAAGGCTTTTGTTGAAAATGCTAGTCATGAGTTACGCACGCCACTTGC
AGTTATCCAAAACCGTTTAGAAGTTCTTTTCCGAAAACCTGAGAGCACCATTTTAGATAATTCTGAGAATATCGCATCAA
GTCTTGATGAAGTACGTAATATGCGTCTTTTGACGACTAATCTCTTGAACTTGGCTCGTCGTGACGATGGTATTAAACCA
GAAATCGAAACCTTAGAACCTGCTTTCTTTGATACAGTATTTACCAACTATGCCATGATTGCAGAAGAAAATGAGAAAGG
TTTCACGGCTCAAAACCAAGTTGGTCGTCCAATCCAGACTGATAAAACGTTATTGAAACAGTTAATGACCATCTTATTTG
ATAATGCTATTAAATATACGGAGGATGACGGACATGTTACCTTTACTGTCCGCACTAATGACCGCCATCTTTATATTTGT
GTAGCTGATAATGGTCCTGGAATATCAGATAGTGATAAGAAAAAAATCTTTGATCGATTTTATCGCGTAGATAAGGCTAG
AACCAGACAAAAAGGTGGGTTTGGACTTGGCTTATCCCTAGCGCAACAAATTGTTTTAGCCCTTAAAGGAACAATTGTTG
TTAAAGATAATCAACCAAAGGGAACGATTTTTGAAGTTAAGATCACCGGAGTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.522

97.665

0.552
  ciaH Streptococcus pneumoniae Rx1

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae D39

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae R6

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae TIGR4

50.216

98.514

0.495