Detailed information NTG0940301

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: V6U62_RS02420
• Genome accession: NZ_CP145860
• Coordinates: 458235..460475 (+)
• Length: 746 a.a.
• NCBI ID: WP_349955294.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS2
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 453235..465475

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U62_RS02395 (V6U62_02385)	-	454534..454803 (-)	270	WP_022496129.1	GIY-YIG nuclease family protein	-
V6U62_RS02400 (V6U62_02390)	-	454807..455571 (-)	765	WP_349955293.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
V6U62_RS02405 (V6U62_02395)	-	455621..456556 (-)	936	WP_022496131.1	polysaccharide deacetylase family protein	-
V6U62_RS02410 (V6U62_02400)	-	456686..457441 (+)	756	WP_022496132.1	lysophospholipid acyltransferase family protein	-
V6U62_RS02415 (V6U62_02405)	comEA	457550..458245 (+)	696	WP_022496133.1	helix-hairpin-helix domain-containing protein	Machinery gene
V6U62_RS02420 (V6U62_02410)	comEC/celB	458235..460475 (+)	2241	WP_349955294.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
V6U62_RS02425 (V6U62_02415)	-	460561..461823 (+)	1263	WP_084915391.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
V6U62_RS02430 (V6U62_02420)	-	461889..462434 (+)	546	WP_013991031.1	GNAT family N-acetyltransferase	-
V6U62_RS02435 (V6U62_02425)	spxR	462427..463707 (+)	1281	WP_002884454.1	CBS-HotDog domain-containing transcription factor SpxR	-
V6U62_RS02440 (V6U62_02430)	-	463752..464612 (+)	861	WP_002884335.1	methionyl aminopeptidase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84435.27 Da
• Isoelectric Point: 9.9046

>NTDB_id=940301 V6U62_RS02420 WP_349955294.1 458235..460475(+) (comEC/celB) [Streptococcus salivarius strain KSS2]
MWLKKAPINLFSLALLIAALYFTIFNTNVYATGVLSFLLGCFLKHHWKNKVALKLVGLVGSFFLVYFLFLHHRATIQDKQ
APTEINQVTLVADTLSVNGEQLSAIGKAKGQTYQVFYRLKSEKEQHFFKTTSQTLVLKGKIKLSLAIGQRNFQGFNYQSY
LASQGIYRMAQIERLDHVVPQKSLSPLAFFHQLRRRALVHIQTHFPNPMRHYMTGLLFGYLGKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKDYLFIILLPFSLCYGLMTGWTASVLRSLIQSLLAEFGIKKLDNMGITLLLLFLF
LPHFLLTVGGVLSCSYAFLLCLFDFEEMSSLKKSICTSLVLSLGILPFLTFYYGTFQPVSLILTAMFSIVFDSFLLPVLT
VFFALSGLVIFSQINPLFEWMEAFLTWIQSWIGQPLILGKPSLFQFGLMIAVLVMLFDFWKKPQFRICLLMIFGLLMVWV
KHPLTNEVTMVDVGQGDSIFLRSMKGDTILIDVGGKVTFGSKEKWQEASQTSNAEKTLIPYLQARGVSQIDHLVLTHTDT
DHIGDLEEVAKRFKIKEICVSQGALTKPSFVKRLRTLKRPVRTLKAGDNLPMMGSKLQVLYPNKVGDGGNNDSIVLYGKL
LGSSFLFTGDLEKEGEEELMVSYPNLKASVLKAGHHGSKGSSSEAFLDQLQPSLALVSAGENNRYKHPNDETLERFKERH
IKVLRTDQNGAIRFKGWFKWSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=940301 V6U62_RS02420 WP_349955294.1 458235..460475(+) (comEC/celB) [Streptococcus salivarius strain KSS2]
ATGTGGCTTAAAAAAGCTCCAATCAATCTTTTTTCCTTGGCTCTGTTAATAGCTGCCCTTTATTTTACGATTTTTAACAC
AAATGTTTATGCTACTGGGGTTTTGTCTTTTCTTTTAGGATGTTTTTTGAAGCATCATTGGAAGAATAAGGTAGCCCTAA
AGTTGGTGGGACTTGTAGGTAGTTTCTTTTTGGTCTACTTTTTATTCTTGCACCACAGAGCTACCATACAAGATAAACAA
GCTCCTACTGAAATCAATCAGGTGACTCTGGTTGCTGATACGCTGTCGGTTAATGGTGAGCAATTATCAGCTATTGGAAA
GGCAAAGGGACAAACTTATCAGGTCTTTTACCGACTCAAATCTGAGAAGGAGCAGCATTTTTTTAAGACTACTAGCCAAA
CGTTGGTATTAAAAGGGAAAATAAAGTTATCCCTAGCAATTGGTCAACGTAATTTTCAAGGGTTTAATTATCAGTCTTAT
CTAGCCAGTCAAGGCATTTATCGAATGGCTCAGATTGAACGCTTGGACCATGTGGTGCCTCAAAAATCTCTATCTCCCCT
AGCTTTTTTCCATCAACTGAGGAGGAGGGCATTGGTTCATATCCAGACGCACTTTCCTAATCCTATGAGACACTATATGA
CAGGTCTGCTCTTTGGGTATTTGGGTAAGGAGTTTGATGAGCAAAGTCAGCTTTACACAAGCTTAGGTATTATTCATCTA
TTCGCACTTTCGGGGATGCAAGTGGGATTTTTTCTGGGATGGTTTCGCTATGGACTCCTACGCTTGGGCCTTCCTAAAGA
TTATCTATTTATTATCTTGCTGCCTTTTTCCTTGTGTTATGGCTTAATGACAGGTTGGACAGCTTCAGTCCTACGTTCCC
TGATTCAAAGTTTGTTAGCGGAGTTTGGTATTAAAAAACTGGATAATATGGGGATAACTTTGCTTCTATTGTTTCTCTTT
TTACCTCATTTTCTTTTGACAGTGGGAGGTGTTTTAAGTTGTTCCTATGCCTTTTTGTTGTGTTTGTTTGATTTTGAGGA
GATGTCATCTCTTAAAAAGTCAATCTGTACGAGCTTAGTGTTGAGTCTTGGGATTTTGCCTTTTCTAACTTTCTATTATG
GGACCTTTCAACCGGTGAGTTTAATTCTGACGGCGATGTTTTCGATAGTATTTGATAGCTTTCTCTTGCCTGTATTGACA
GTCTTCTTTGCTCTTTCAGGACTGGTAATCTTTTCTCAAATCAACCCACTTTTTGAATGGATGGAGGCCTTTTTGACTTG
GATACAATCCTGGATAGGCCAGCCTTTGATTTTAGGGAAACCTAGTTTGTTTCAGTTTGGCTTGATGATAGCTGTCTTGG
TTATGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGGATTTGCCTTTTGATGATTTTTGGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAACCAATGAGGTGACTATGGTTGACGTTGGTCAGGGAGATAGTATTTTTCTGAGGAGTATGAAAGGCGA
TACCATCCTAATTGATGTGGGTGGCAAGGTGACTTTCGGGTCAAAGGAAAAATGGCAAGAGGCTAGCCAGACGAGCAATG
CGGAGAAAACCTTGATTCCCTACCTACAGGCTAGGGGAGTGTCTCAAATTGACCATCTGGTCCTGACTCATACGGATACA
GACCATATTGGTGATTTGGAAGAAGTAGCCAAGCGGTTTAAGATTAAGGAAATCTGTGTCAGTCAAGGAGCTTTGACTAA
GCCTAGTTTTGTGAAACGACTTCGAACTTTAAAACGCCCAGTTCGCACTCTAAAGGCTGGAGACAACTTACCCATGATGG
GAAGTAAGCTACAGGTTCTTTATCCAAATAAAGTTGGTGATGGTGGTAACAACGATTCGATAGTTCTTTACGGAAAACTA
TTAGGAAGTAGTTTTTTGTTTACGGGTGATCTAGAAAAAGAAGGAGAGGAGGAACTGATGGTCAGCTATCCTAATTTAAA
GGCTAGTGTCCTCAAAGCCGGACACCACGGTTCAAAAGGGTCATCGTCTGAAGCGTTTTTGGACCAGTTGCAGCCCTCCC
TTGCCCTTGTTTCAGCTGGTGAGAATAATCGTTATAAACATCCAAATGATGAAACTTTGGAGCGTTTCAAGGAACGTCAC
ATTAAGGTTTTACGAACAGACCAGAACGGTGCTATCCGTTTTAAGGGGTGGTTTAAGTGGTCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-462)

• Domain of unknown function (DUF4131) (DUF4131) (29-169)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-699)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	48.594	100	0.487
comEC/celB	Streptococcus mitis SK321	48.262	100	0.484
comEC/celB	Streptococcus pneumoniae Rx1	47.193	100	0.473
comEC/celB	Streptococcus pneumoniae D39	47.193	100	0.473
comEC/celB	Streptococcus pneumoniae R6	47.193	100	0.473
comEC/celB	Streptococcus pneumoniae TIGR4	47.059	100	0.472
comEC	Lactococcus lactis subsp. cremoris KW2	43.514	99.196	0.432