Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   V6T01_RS05950 Genome accession   NZ_CP145856
Coordinates   1222152..1223567 (-) Length   471 a.a.
NCBI ID   WP_410541498.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS1     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1217152..1228567
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6T01_RS05920 (V6T01_05905) - 1217782..1218180 (-) 399 WP_002891126.1 cytidine deaminase -
  V6T01_RS05925 (V6T01_05910) deoC 1218167..1218829 (-) 663 WP_048790410.1 deoxyribose-phosphate aldolase -
  V6T01_RS05930 (V6T01_05915) - 1218864..1220141 (-) 1278 WP_073689921.1 pyrimidine-nucleoside phosphorylase -
  V6T01_RS05935 (V6T01_05920) - 1220138..1220728 (-) 591 WP_073689922.1 class I SAM-dependent methyltransferase -
  V6T01_RS05940 (V6T01_05925) coaA 1220841..1221761 (+) 921 WP_013990467.1 type I pantothenate kinase -
  V6T01_RS05945 (V6T01_05930) rpsT 1221831..1222067 (+) 237 WP_004182129.1 30S ribosomal protein S20 -
  V6T01_RS05950 (V6T01_05935) ciaH 1222152..1223567 (-) 1416 WP_410541498.1 sensor histidine kinase Regulator
  V6T01_RS05955 (V6T01_05940) ciaR 1223557..1224231 (-) 675 WP_002891134.1 response regulator transcription factor Regulator
  V6T01_RS05960 (V6T01_05945) - 1224429..1226099 (-) 1671 WP_247924893.1 formate--tetrahydrofolate ligase -
  V6T01_RS05965 (V6T01_05950) - 1226293..1226976 (+) 684 WP_410541497.1 phosphopantothenate--cysteine ligase -
  V6T01_RS05970 (V6T01_05955) coaC 1226969..1227514 (+) 546 WP_410541496.1 phosphopantothenoylcysteine decarboxylase -
  V6T01_RS05975 (V6T01_05960) - 1227543..1228115 (+) 573 WP_004182389.1 ECF transporter S component -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53449.18 Da        Isoelectric Point: 8.7681

>NTDB_id=940184 V6T01_RS05950 WP_410541498.1 1222152..1223567(-) (ciaH) [Streptococcus salivarius strain KSS1]
MLTKFFNYLFRRIKSEGFKSFIHFFATFSGIFLVMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDTKGSTDETPDSSGSKKESKKKSKMEDAPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTGQNQVGRPIHTDKTLLKQLMTILFDNAIKYTEDDGHVTFTVRTNDRHLYIS
VADNGPGISDSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVLALKGTIVVKDNQPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=940184 V6T01_RS05950 WP_410541498.1 1222152..1223567(-) (ciaH) [Streptococcus salivarius strain KSS1]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATCAAGTCAGAAGGATTTAAGTCTTTCATTCATTTCTTTGCCAC
TTTTTCTGGTATTTTCCTTGTCATGACTGTCATGATTTTGCAGATTCTGAGTTACGGCGTTTATTCCAATGTGGACTCTA
GTCTGAAAATGGCAGCAACTAAGACCAATTCTTATTTAGAAATGGAAATGCTAAAACGGGAACTTTTTCTGACTTCTGAG
GTAGATCAAAATAATACGACAACCATCTACCAAGCCTATGATACTAAAGGGTCGACAGATGAAACACCTGACTCGAGTGG
CTCTAAAAAAGAATCTAAGAAGAAATCAAAGATGGAAGATGCCCCACACGATTTATCTGTTGCGGCGAATACCAGTGTCT
TAGTGCTTGATAAGAATGGAAAAGTCCTCAATGTCGTTGACAAATTTTCTAGCTTATCCAATTTACCAATAGATAAAAAT
AACATTGATGTTATCAGCAAGGGAAGCGCTCAGAATTATTTCGATCAAACCGAAAAGTATCGCCTGATTACTGAAAAAGT
AGATAATAGTCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCCACTGAACGTT
ATGTCAAGCTCATTGTCATCATGATGAGTTTCTTCTGGCTCCTATCTGTTGCGGCTAGTATGTATTTGGCCAAGTGGTCA
AGACGTCCTATCCAGGAAAGTCTGGAGAAGCAGAAGGCATTTGTTGAAAATGCCAGTCACGAGTTACGGACACCGCTTGC
TGTGATTCAAAACCGATTAGAAGTTCTTTTCCGCAAGCCTGAGAGCACCATTTTAGATAATTCAGAGAATATTGCTTCAA
GTCTTGATGAAGTACGTAATATGCGTCTGTTGACGACAAATCTCTTGAACTTGGCTCGTCGTGACGATGGTATTAAGCCG
GAAATCGAAACCTTAGAACCTGCTTTCTTTGATACAGTATTTACCAATTATGCTATGATTGCTGAAGAAAATGAGAAAGG
TTTCACGGGTCAAAACCAAGTTGGTCGTCCAATCCATACTGATAAAACGCTATTGAAGCAGCTAATGACCATATTATTTG
ATAATGCTATTAAATATACGGAAGATGATGGACATGTTACCTTTACTGTTCGCACTAATGACCGCCATCTTTATATTTCT
GTAGCTGATAATGGTCCTGGTATATCAGATAGTGATAAGAAAAAAATCTTTGATCGATTTTATCGCGTAGATAAGGCTAG
AACCAGACAAAAAGGTGGGTTTGGACTGGGCTTATCACTAGCGCAACAAATTGTTTTAGCTCTTAAAGGAACAATTGTTG
TTAAAGATAATCAACCCAAAGGAACGATTTTTGAAGTTAAGATCACTGGAGTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.304

97.665

0.55
  ciaH Streptococcus pneumoniae Rx1

50

98.514

0.493
  ciaH Streptococcus pneumoniae D39

50

98.514

0.493
  ciaH Streptococcus pneumoniae R6

50

98.514

0.493
  ciaH Streptococcus pneumoniae TIGR4

50

98.514

0.493