Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   ACEY2B_RS03560 Genome accession   NZ_CP169315
Coordinates   689246..690616 (+) Length   456 a.a.
NCBI ID   WP_042230545.1    Uniprot ID   -
Organism   Lactococcus lactis strain IFLLLBEK1     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 684246..695616
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACEY2B_RS03545 (ACEY2B_03545) - 684924..687179 (+) 2256 WP_015426863.1 glycoside hydrolase family 65 protein -
  ACEY2B_RS03550 (ACEY2B_03550) - 687332..688306 (+) 975 WP_015426862.1 LacI family DNA-binding transcriptional regulator -
  ACEY2B_RS03555 (ACEY2B_03555) ciaR 688484..689152 (+) 669 WP_021722129.1 response regulator transcription factor Regulator
  ACEY2B_RS03560 (ACEY2B_03560) ciaH 689246..690616 (+) 1371 WP_042230545.1 cell wall metabolism sensor histidine kinase WalK Regulator
  ACEY2B_RS03565 (ACEY2B_03565) - 690764..692506 (+) 1743 WP_374788225.1 1-deoxy-D-xylulose-5-phosphate synthase -
  ACEY2B_RS03570 (ACEY2B_03570) yidD 692623..692889 (+) 267 WP_015426859.1 membrane protein insertion efficiency factor YidD -
  ACEY2B_RS03575 (ACEY2B_03575) - 693011..694444 (+) 1434 WP_021722126.1 6-phospho-beta-glucosidase -

Sequence

Protein


Download         Length: 456 a.a.        Molecular weight: 51417.98 Da        Isoelectric Point: 9.4537

>NTDB_id=939003 ACEY2B_RS03560 WP_042230545.1 689246..690616(+) (ciaH) [Lactococcus lactis strain IFLLLBEK1]
MKKIIKKIKSSAIVKNDGKNFLHFFLAFTVIFVALAVIIIQVMQLGMYRATDQNLHNLAQNRVFLEEAANNQLGTNNSQD
SGFYGPNNSVIFYDSEGKNFMPSTGSNANISTNFGMSLLQKAMKFNEKHINTIQTVSVKNPYGDNLHYRYYTTSQFIITN
SDGTVTPVYMQIFSNVDQIQDAMSRAMWVIVTTMITFWLLSIIISLYLANWTLRPILAAYEKQKEFVENASHELRTPLAI
LQNRLELLFQKPTATIIDESENISESLSEVRNMRLLTSNLLNLARRDSGIRIEPEATTATYFENIFNSYEMLAENAGKKF
SGHLKLDGTINLDQALIKQLLTILFDNALKYTGDEGEISVDVQKNGGFLVFAVADNGEGISDEDKKKIFDRFFRVDKART
RQKGGLGLGLSLAKQIVEAYNGKITVEDNKPKGTKFIVRIRVDSTISNPAKIFQKL

Nucleotide


Download         Length: 1371 bp        

>NTDB_id=939003 ACEY2B_RS03560 WP_042230545.1 689246..690616(+) (ciaH) [Lactococcus lactis strain IFLLLBEK1]
TTGAAGAAAATAATTAAAAAAATTAAATCTTCAGCTATTGTAAAAAATGATGGGAAAAATTTCCTTCATTTTTTTCTAGC
TTTTACAGTCATTTTTGTTGCTTTAGCCGTGATTATTATTCAAGTCATGCAATTAGGAATGTATCGAGCGACTGACCAAA
ATTTACACAATTTGGCTCAAAACCGAGTGTTTTTGGAAGAAGCAGCGAATAATCAATTAGGAACAAATAATTCACAAGAT
AGTGGCTTTTATGGACCAAATAATAGTGTAATTTTTTATGATTCAGAAGGAAAAAACTTTATGCCATCAACGGGCTCAAA
TGCAAATATAAGTACAAACTTTGGCATGAGTCTTTTGCAAAAAGCAATGAAATTTAATGAAAAACATATAAATACAATTC
AGACAGTATCTGTAAAAAATCCTTATGGAGATAATTTGCACTATCGTTATTACACAACATCGCAATTTATCATTACAAAT
TCAGATGGTACTGTGACGCCAGTTTATATGCAAATTTTTTCAAACGTTGACCAAATTCAAGATGCCATGAGCCGGGCCAT
GTGGGTCATTGTGACAACAATGATTACTTTCTGGCTACTATCAATAATTATTAGTCTATATCTTGCAAACTGGACTTTAA
GACCTATTCTGGCTGCTTATGAAAAACAAAAAGAATTTGTTGAAAATGCTTCACATGAATTGAGAACACCTCTGGCAATC
TTGCAAAATCGTCTAGAATTACTTTTCCAAAAGCCAACCGCAACAATTATTGATGAATCAGAAAATATTTCTGAAAGTTT
ATCAGAAGTTCGTAATATGCGTTTATTAACAAGTAACTTACTGAACTTAGCTCGTCGAGATTCTGGAATCAGAATTGAGC
CAGAGGCGACTACGGCAACTTATTTTGAGAATATTTTTAATAGCTATGAAATGCTTGCTGAAAACGCAGGTAAAAAGTTT
TCAGGCCATTTGAAATTAGATGGAACGATTAATTTGGACCAAGCCCTGATTAAACAATTGCTGACCATCTTATTTGATAA
TGCTCTTAAATACACGGGTGATGAGGGTGAAATCTCTGTAGATGTTCAAAAAAATGGGGGATTCTTAGTTTTTGCTGTCG
CCGATAATGGTGAAGGAATTTCTGATGAAGATAAGAAAAAAATCTTTGACCGCTTTTTCCGAGTAGATAAAGCAAGAACG
CGTCAAAAAGGTGGCTTAGGTTTGGGTCTTTCTCTGGCCAAACAAATTGTTGAAGCTTACAATGGGAAGATTACAGTTGA
AGATAATAAACCTAAAGGTACAAAATTCATTGTTAGAATTCGTGTGGATAGCACAATTTCAAATCCTGCAAAAATTTTCC
AAAAGTTGTAA

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(223-289)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(333-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

48.372

94.298

0.456
  ciaH Streptococcus pneumoniae Rx1

44.866

98.246

0.441
  ciaH Streptococcus pneumoniae D39

44.866

98.246

0.441
  ciaH Streptococcus pneumoniae R6

44.866

98.246

0.441
  ciaH Streptococcus pneumoniae TIGR4

44.866

98.246

0.441