Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACEPOS_RS10615 Genome accession   NZ_CP168497
Coordinates   2151116..2151739 (+) Length   207 a.a.
NCBI ID   WP_271019658.1    Uniprot ID   -
Organism   Staphylococcus aureus strain J23     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2146116..2156739
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACEPOS_RS10595 (ACEPOS_10595) - 2146558..2146953 (+) 396 WP_000901023.1 hypothetical protein -
  ACEPOS_RS10600 (ACEPOS_10600) fumC 2147149..2148534 (+) 1386 WP_271019657.1 class II fumarate hydratase -
  ACEPOS_RS10605 (ACEPOS_10605) - 2148998..2149819 (-) 822 WP_020977385.1 RluA family pseudouridine synthase -
  ACEPOS_RS10610 (ACEPOS_10610) - 2149982..2151094 (+) 1113 WP_000437967.1 GAF domain-containing sensor histidine kinase -
  ACEPOS_RS10615 (ACEPOS_10615) vraR 2151116..2151739 (+) 624 WP_271019658.1 response regulator transcription factor Regulator
  ACEPOS_RS10620 (ACEPOS_10620) - 2152095..2152559 (+) 465 WP_000375864.1 helix-turn-helix transcriptional regulator -
  ACEPOS_RS10625 (ACEPOS_10625) - 2152738..2153862 (+) 1125 WP_020977384.1 DUF445 domain-containing protein -
  ACEPOS_RS10630 (ACEPOS_10630) - 2153931..2154275 (+) 345 WP_000290301.1 YlbF/YmcA family competence regulator -
  ACEPOS_RS10635 (ACEPOS_10635) - 2155198..2156394 (+) 1197 WP_020977383.1 exonuclease SbcCD subunit D -

Sequence

Protein


Download         Length: 207 a.a.        Molecular weight: 23823.50 Da        Isoelectric Point: 5.8099

>NTDB_id=936112 ACEPOS_RS10615 WP_271019658.1 2151116..2151739(+) (vraR) [Staphylococcus aureus strain J23]
MNKVILVDDHYIVRQGLRFLLSTIENIEVLQDFADGETFLEYLKGHEHPDIVLLDLVMPGMNGIEITEYIKAHYPDIKVL
VLTSYVDDEHVISAINKGADGYEMKDVEPQQLIETIRRVMNGEKMIHPKAQDVFETVSQKPHYTNKLSKREIEVLREMVK
GKTNKEIAETLFVSEKTIKTHVSHIFSKLQVSDRTQAAIYAMENKLI

Nucleotide


Download         Length: 624 bp        

>NTDB_id=936112 ACEPOS_RS10615 WP_271019658.1 2151116..2151739(+) (vraR) [Staphylococcus aureus strain J23]
ATGAACAAAGTAATATTAGTAGATGACCATTATATTGTGCGACAAGGATTGCGATTTTTATTATCCACGATTGAAAACAT
AGAAGTTTTACAAGACTTTGCAGATGGAGAAACATTTTTAGAATATTTAAAAGGGCATGAGCACCCTGATATTGTGCTAT
TAGATTTAGTGATGCCTGGCATGAATGGTATTGAAATTACGGAATATATTAAGGCACATTATCCGGATATTAAAGTTTTG
GTATTAACAAGTTATGTTGATGATGAACATGTAATTTCAGCAATCAATAAAGGTGCTGATGGATATGAAATGAAAGACGT
TGAGCCTCAGCAGTTAATTGAAACTATTAGACGAGTTATGAACGGTGAAAAAATGATACATCCTAAGGCACAAGATGTAT
TCGAAACAGTTAGCCAAAAACCACACTACACGAATAAGTTGTCAAAGAGAGAAATTGAAGTGTTACGTGAAATGGTTAAA
GGTAAAACAAATAAAGAGATAGCAGAAACTTTATTTGTATCTGAAAAAACAATTAAAACACATGTCAGTCATATATTTAG
TAAATTACAAGTTAGCGATCGTACACAAGCAGCAATTTATGCAATGGAAAATAAGTTGATTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(146-201)

Response regulator receiver domain (Response_reg)

(4-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.58

100

0.406
  degU Bacillus subtilis subsp. subtilis str. 168

34.685

100

0.372
  letA Legionella pneumophila str. Paris

35.714

100

0.362
  letA Legionella pneumophila strain ERS1305867

35.714

100

0.362