Detailed information
Bioinformatically predicted
Overview
| Name | dprA | Type | Machinery gene |
| Locus tag | MWM20_RS02235 | Genome accession | NZ_AP025677 |
| Coordinates | 457589..458713 (+) | Length | 374 a.a. |
| NCBI ID | WP_000228517.1 | Uniprot ID | E2QFE2 |
| Organism | Escherichia coli strain Rb-23 | ||
| Function | ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 435748..458713 | 457589..458713 | within | 0 |
Gene organization within MGE regions
Location: 435748..458713
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MWM20_RS02045 (TRECRb23_04020) | gspA | 435748..437217 (+) | 1470 | WP_000107580.1 | type II secretion system protein GspA | - |
| MWM20_RS02050 (TRECRb23_04030) | gspB | 437219..437638 (+) | 420 | WP_000461439.1 | putative general secretion pathway protein GspB | - |
| MWM20_RS02055 (TRECRb23_04040) | rpsJ | 437876..438187 (+) | 312 | WP_001181004.1 | 30S ribosomal protein S10 | - |
| MWM20_RS02060 (TRECRb23_04050) | rplC | 438220..438849 (+) | 630 | WP_000579833.1 | 50S ribosomal protein L3 | - |
| MWM20_RS02065 (TRECRb23_04060) | rplD | 438860..439465 (+) | 606 | WP_000424395.1 | 50S ribosomal protein L4 | - |
| MWM20_RS02070 (TRECRb23_04070) | rplW | 439462..439764 (+) | 303 | WP_000617544.1 | 50S ribosomal protein L23 | - |
| MWM20_RS02075 (TRECRb23_04080) | rplB | 439782..440603 (+) | 822 | WP_000301864.1 | 50S ribosomal protein L2 | - |
| MWM20_RS02080 (TRECRb23_04090) | rpsS | 440620..440898 (+) | 279 | WP_001138117.1 | 30S ribosomal protein S19 | - |
| MWM20_RS02085 (TRECRb23_04100) | rplV | 440913..441245 (+) | 333 | WP_000447529.1 | 50S ribosomal protein L22 | - |
| MWM20_RS02090 (TRECRb23_04110) | rpsC | 441263..441964 (+) | 702 | WP_000529945.1 | 30S ribosomal protein S3 | - |
| MWM20_RS02095 (TRECRb23_04120) | rplP | 441977..442387 (+) | 411 | WP_000941212.1 | 50S ribosomal protein L16 | - |
| MWM20_RS02100 (TRECRb23_04130) | rpmC | 442387..442578 (+) | 192 | WP_000644741.1 | 50S ribosomal protein L29 | - |
| MWM20_RS02105 (TRECRb23_04140) | rpsQ | 442578..442832 (+) | 255 | WP_000130100.1 | 30S ribosomal protein S17 | - |
| MWM20_RS02110 (TRECRb23_04150) | rplN | 442997..443368 (+) | 372 | WP_000613955.1 | 50S ribosomal protein L14 | - |
| MWM20_RS02115 (TRECRb23_04160) | rplX | 443379..443693 (+) | 315 | WP_000729186.1 | 50S ribosomal protein L24 | - |
| MWM20_RS02120 (TRECRb23_04170) | rplE | 443708..444247 (+) | 540 | WP_001096200.1 | 50S ribosomal protein L5 | - |
| MWM20_RS02125 (TRECRb23_04180) | rpsN | 444262..444567 (+) | 306 | WP_001118930.1 | 30S ribosomal protein S14 | - |
| MWM20_RS02130 (TRECRb23_04190) | rpsH | 444601..444993 (+) | 393 | WP_000062611.1 | 30S ribosomal protein S8 | - |
| MWM20_RS02135 (TRECRb23_04200) | rplF | 445006..445539 (+) | 534 | WP_000091945.1 | 50S ribosomal protein L6 | - |
| MWM20_RS02140 (TRECRb23_04210) | rplR | 445549..445902 (+) | 354 | WP_000358960.1 | 50S ribosomal protein L18 | - |
| MWM20_RS02145 (TRECRb23_04220) | rpsE | 445917..446420 (+) | 504 | WP_000940121.1 | 30S ribosomal protein S5 | - |
| MWM20_RS02150 (TRECRb23_04230) | rpmD | 446424..446603 (+) | 180 | WP_001140433.1 | 50S ribosomal protein L30 | - |
| MWM20_RS02155 (TRECRb23_04240) | rplO | 446607..447041 (+) | 435 | WP_001238917.1 | 50S ribosomal protein L15 | - |
| MWM20_RS02160 (TRECRb23_04250) | secY | 447049..448380 (+) | 1332 | WP_001118861.1 | preprotein translocase subunit SecY | - |
| MWM20_RS02165 | rpmJ | 448412..448528 (+) | 117 | WP_000868187.1 | 50S ribosomal protein L36 | - |
| MWM20_RS02170 (TRECRb23_04260) | rpsM | 448675..449031 (+) | 357 | WP_000090775.1 | 30S ribosomal protein S13 | - |
| MWM20_RS02175 (TRECRb23_04270) | rpsK | 449048..449437 (+) | 390 | WP_001029684.1 | 30S ribosomal protein S11 | - |
| MWM20_RS02180 (TRECRb23_04280) | rpsD | 449471..450091 (+) | 621 | WP_000135224.1 | 30S ribosomal protein S4 | - |
| MWM20_RS02185 (TRECRb23_04290) | rpoA | 450117..451106 (+) | 990 | WP_001162094.1 | DNA-directed RNA polymerase subunit alpha | - |
| MWM20_RS02190 (TRECRb23_04300) | rplQ | 451147..451530 (+) | 384 | WP_001216368.1 | 50S ribosomal protein L17 | - |
| MWM20_RS02195 (TRECRb23_04310) | yhdN | 451637..452005 (+) | 369 | WP_000266505.1 | DUF1992 domain-containing protein | - |
| MWM20_RS02200 (TRECRb23_04320) | zntR | 452016..452441 (+) | 426 | WP_000285607.1 | Zn(2+)-responsive transcriptional regulator | - |
| MWM20_RS02205 (TRECRb23_04330) | arfA | 452497..452715 (+) | 219 | WP_000092695.1 | alternative ribosome-rescue factor ArfA | - |
| MWM20_RS02210 (TRECRb23_04340) | mscL | 452712..453125 (-) | 414 | WP_000022450.1 | large-conductance mechanosensitive channel protein MscL | - |
| MWM20_RS02215 (TRECRb23_04350) | trkA | 453255..454631 (-) | 1377 | WP_000691382.1 | Trk system potassium transporter TrkA | - |
| MWM20_RS02220 (TRECRb23_04360) | rsmB | 454653..455942 (-) | 1290 | WP_000744788.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| MWM20_RS02225 (TRECRb23_04370) | fmt | 455988..456935 (-) | 948 | WP_000004422.1 | methionyl-tRNA formyltransferase | - |
| MWM20_RS02230 (TRECRb23_04380) | def | 456950..457459 (-) | 510 | WP_000114984.1 | peptide deformylase | - |
| MWM20_RS02235 (TRECRb23_04390) | dprA | 457589..458713 (+) | 1125 | WP_000228517.1 | DNA-protecting protein DprA | Machinery gene |
Sequence
Protein
Download Length: 374 a.a. Molecular weight: 40910.86 Da Isoelectric Point: 6.0395
>NTDB_id=93517 MWM20_RS02235 WP_000228517.1 457589..458713(+) (dprA) [Escherichia coli strain Rb-23]
MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHAPLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV
MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHAPLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV
Nucleotide
Download Length: 1125 bp
>NTDB_id=93517 MWM20_RS02235 WP_000228517.1 457589..458713(+) (dprA) [Escherichia coli strain Rb-23]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTATGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGTTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGGTTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTTAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCTCCACTGGCTGCCAGTCTACT
TGAGCAAGGTGGTGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAGGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCTTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTATGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGTTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGGTTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTTAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCTCCACTGGCTGCCAGTCTACT
TGAGCAAGGTGGTGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAGGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCTTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| dprA | Vibrio campbellii strain DS40M4 |
48.78 |
98.663 |
0.481 |
| dprA | Vibrio cholerae strain A1552 |
49.355 |
82.888 |
0.409 |
| dprA | Glaesserella parasuis strain SC1401 |
44.807 |
90.107 |
0.404 |
| dprA | Haemophilus influenzae Rd KW20 |
44.214 |
90.107 |
0.398 |
| dprA | Legionella pneumophila strain ERS1305867 |
44.242 |
88.235 |
0.39 |