Detailed information NTG0933997

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: ACDZ04_RS05975
• Genome accession: NZ_CP168017
• Coordinates: 1241022..1241795 (+)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus strain sa230502_barcode25
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1236022..1246795

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACDZ04_RS05955 (ACDZ04_05955)	trmFO	1236365..1237672 (+)	1308	WP_000195263.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
ACDZ04_RS05960 (ACDZ04_05960)	xerC	1238090..1238986 (+)	897	WP_001015609.1	tyrosine recombinase XerC	-
ACDZ04_RS05965 (ACDZ04_05965)	hslV	1238983..1239528 (+)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
ACDZ04_RS05970 (ACDZ04_05970)	hslU	1239594..1240997 (+)	1404	WP_000379051.1	ATP-dependent protease ATPase subunit HslU	-
ACDZ04_RS05975 (ACDZ04_05975)	codY	1241022..1241795 (+)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
ACDZ04_RS05980 (ACDZ04_05980)	-	1241846..1241938 (+)	93	WP_031788481.1	hypothetical protein	-
ACDZ04_RS05985 (ACDZ04_05985)	rpsB	1242137..1242904 (+)	768	WP_000268484.1	30S ribosomal protein S2	-
ACDZ04_RS05990 (ACDZ04_05990)	-	1242938..1243051 (+)	114	WP_001791405.1	hypothetical protein	-
ACDZ04_RS05995 (ACDZ04_05995)	tsf	1243086..1243967 (+)	882	WP_000201387.1	translation elongation factor Ts	-
ACDZ04_RS06000 (ACDZ04_06000)	pyrH	1244104..1244826 (+)	723	WP_000057330.1	UMP kinase	-
ACDZ04_RS06005 (ACDZ04_06005)	frr	1244845..1245399 (+)	555	WP_001280006.1	ribosome recycling factor	-
ACDZ04_RS06010 (ACDZ04_06010)	-	1245772..1246542 (+)	771	WP_000473705.1	isoprenyl transferase	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=933997 ACDZ04_RS05975 WP_000055337.1 1241022..1241795(+) (codY) [Staphylococcus aureus strain sa230502_barcode25]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=933997 ACDZ04_RS05975 WP_000055337.1 1241022..1241795(+) (codY) [Staphylococcus aureus strain sa230502_barcode25]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGCGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACACGATG
ACTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCAAT
TGAACATATCTTTGAAGAACTTGGCGGTACAGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAGTAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428