Detailed information NTG0933137

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: V3434_RS00155
• Genome accession: NZ_CP144271
• Coordinates: 28697..29740 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain LA31
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 23697..34740

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V3434_RS00125 (V3434_00125)	-	24118..25374 (-)	1257	WP_074347694.1	aminopeptidase	-
V3434_RS00130 (V3434_00130)	-	25377..25577 (-)	201	WP_000180460.1	DUF1128 family protein	-
V3434_RS00135 (V3434_00135)	-	25724..26188 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
V3434_RS00140 (V3434_00140)	-	26195..26470 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
V3434_RS00145 (V3434_00145)	-	26748..27965 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
V3434_RS00150 (V3434_00150)	vraR	28078..28707 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
V3434_RS00155 (V3434_00155)	vraS	28697..29740 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
V3434_RS00160 (V3434_00160)	liaF	29737..30438 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
V3434_RS00165 (V3434_00165)	-	30453..30839 (-)	387	WP_001110182.1	hypothetical protein	-
V3434_RS00170 (V3434_00170)	map	31056..31814 (-)	759	WP_000636145.1	type I methionyl aminopeptidase	-
V3434_RS00175 (V3434_00175)	-	32288..33274 (+)	987	WP_000999712.1	aromatic acid exporter family protein	-
V3434_RS00180 (V3434_00180)	-	33463..33876 (-)	414	WP_025174370.1	hypothetical protein	-
V3434_RS00185 (V3434_00185)	-	33905..34015 (-)	111	WP_014937049.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=933137 V3434_RS00155 WP_001017131.1 28697..29740(-) (vraS) [Staphylococcus aureus strain LA31]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=933137 V3434_RS00155 WP_001017131.1 28697..29740(-) (vraS) [Staphylococcus aureus strain LA31]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1