Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   ACB327_RS00670 Genome accession   NZ_CP167020
Coordinates   104231..104659 (+) Length   142 a.a.
NCBI ID   WP_076639399.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Isolate 6     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 99231..109659
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB327_RS00650 (ACB327_00650) - 101562..101927 (+) 366 WP_002986560.1 DUF1033 family protein -
  ACB327_RS00655 (ACB327_00655) comGA 102020..102958 (+) 939 WP_002986557.1 competence type IV pilus ATPase ComGA Machinery gene
  ACB327_RS00660 (ACB327_00660) comGB 102894..103928 (+) 1035 WP_228631569.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACB327_RS00665 (ACB327_00665) comGC 103930..104256 (+) 327 WP_011528161.1 competence type IV pilus major pilin ComGC Machinery gene
  ACB327_RS00670 (ACB327_00670) comGD 104231..104659 (+) 429 WP_076639399.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACB327_RS00675 (ACB327_00675) comGE 104616..104900 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACB327_RS00680 (ACB327_00680) comGF 104893..105327 (+) 435 WP_002986542.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACB327_RS00685 (ACB327_00685) comGG 105311..105637 (+) 327 WP_002986539.1 competence type IV pilus minor pilin ComGG -
  ACB327_RS00690 (ACB327_00690) comGH 105735..106688 (+) 954 WP_129322573.1 class I SAM-dependent methyltransferase Machinery gene
  ACB327_RS00695 (ACB327_00695) - 106747..107943 (+) 1197 WP_020904834.1 acetate kinase -
  ACB327_RS00700 (ACB327_00700) - 108130..108438 (+) 309 Protein_89 hypothetical protein -
  ACB327_RS00705 (ACB327_00705) proC 108521..109291 (-) 771 WP_076639397.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16338.09 Da        Isoelectric Point: 10.3481

>NTDB_id=931350 ACB327_RS00670 WP_076639399.1 104231..104659(+) (comGD) [Streptococcus pyogenes strain Isolate 6]
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTE
GNSLTVPKSITVNHPYRLVIDQMGGNHSLVKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP

Nucleotide


Download         Length: 429 bp        

>NTDB_id=931350 ACB327_RS00670 WP_076639399.1 104231..104659(+) (comGD) [Streptococcus pyogenes strain Isolate 6]
ATGAAAAAGCCCGTCTTAGCAATTAAAGCTTTTACTTTGCTTGAAACTTTACTAAGTTTGTCAGTGATGAGTTTCATTAT
ATTGGGATTGTCTGTACCAGTGACAAAAAGCTATCAAAAAGTAGAAGAGCATCTGTTTTTTAGCCATTTTGAACATTTGT
ATCGACATCAGCAAAAGTTAGCCATATTACAGCAAAAACAGCGCGTCTTGGATATTTCTTCAACAAAAATTGTTACAGAA
GGTAATAGCCTAACAGTTCCTAAATCAATAACAGTGAATCATCCTTATCGGTTAGTTATTGATCAGATGGGAGGCAACCA
TTCCTTAGTTAAAATTATTTTTGACATGACTGATCGACGCTTTAAATACCAATTTTATCTAGGGAGTGGGAATTATCAAA
AAACAAGTCAAAGCTTACATAGCCCTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus mutans UA140

45.736

90.845

0.415
  comGD Streptococcus mutans UA159

45.736

90.845

0.415
  comGD/cglD Streptococcus mitis NCTC 12261

39.706

95.775

0.38
  comGD Streptococcus gordonii str. Challis substr. CH1

40.458

92.254

0.373