Detailed information NTG0930829

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: ACB359_RS05365
• Genome accession: NZ_CP167013
• Coordinates: 1078172..1080415 (-)
• Length: 747 a.a.
• NCBI ID: WP_031488547.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 16
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1073172..1085415

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB359_RS05335 (ACB359_05335)	-	1073770..1074990 (+)	1221	WP_002983986.1	DUF3114 domain-containing protein	-
ACB359_RS05340 (ACB359_05340)	-	1075144..1075734 (-)	591	WP_002983984.1	serine hydrolase	-
ACB359_RS05345 (ACB359_05345)	-	1075731..1075958 (-)	228	WP_226316535.1	hypothetical protein	-
ACB359_RS05350 (ACB359_05350)	-	1075959..1076192 (-)	234	WP_002983979.1	hypothetical protein	-
ACB359_RS05355 (ACB359_05355)	sodA	1076359..1076964 (-)	606	WP_002983977.1	superoxide dismutase SodA	-
ACB359_RS05360 (ACB359_05360)	holA	1077061..1078101 (-)	1041	WP_031488548.1	DNA polymerase III subunit delta	-
ACB359_RS05365 (ACB359_05365)	comEC/celB	1078172..1080415 (-)	2244	WP_031488547.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ACB359_RS05370 (ACB359_05370)	-	1080396..1081058 (-)	663	WP_002983967.1	ComEA family DNA-binding protein	-
ACB359_RS05375 (ACB359_05375)	-	1081258..1081998 (-)	741	WP_031488546.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
ACB359_RS05380 (ACB359_05380)	-	1082116..1082892 (+)	777	WP_010922438.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
ACB359_RS05385 (ACB359_05385)	-	1082882..1083160 (+)	279	WP_011017953.1	GIY-YIG nuclease family protein	-
ACB359_RS05390 (ACB359_05390)	-	1083184..1085184 (-)	2001	WP_371399853.1	KUP/HAK/KT family potassium transporter	-

Sequence

Protein

• Length: 747 a.a.
• Molecular weight: 85629.49 Da
• Isoelectric Point: 9.6423

>NTDB_id=930829 ACB359_RS05365 WP_031488547.1 1078172..1080415(-) (comEC/celB) [Streptococcus pyogenes strain Isolate 16]
MTFSWTKLVPLSKIQFAFLILVFFYQIHSPSWLTFLLSLSLICLLVKRLSKKEFLGVFAILSFCALFLLYQKQQLVQKLE
IQPVQITSVALVPDSIRINGDQLAVLGRHGKHSYQLFYRLKSQAEAQLFKKEHRWLVMHAKVTLEKAEEVRNFKGFNYQT
FLAYQGIYRIGKVEQIEQLEVISPESICDYLSSLRRRAIVHCQQHFPRPMSHYLTGLLFGYLDKSFGEMTDYYSQLGIIH
LFALSGMQVGFFLTCFRRVLLLLAVPLEWIKWIELPFASFYAALTGYSISVIRSLVQSQLRHLGIKGLDNLACTFLLVFL
WDAHFLMTVGGVLTFSYAFLLTVVTVEELSGAKRQLVQVLTISLGILPFLLFYFSSFNPMSMVLTGLLSYLFDLFILPLL
CLVFCLSPLVTVSICNHLFILLEKVIQFLGNTFNSSLVFGSPTSWHLLILVISFAIFYDYRQVRQRVITCGLVIALTLLS
VKYPLTNEVTFIDIGQGDSILVREWTGKNLLIDVGGRPFFSSKEHWRREYHVANAQKTLIPYLKSRGIHTIDQLLVTHAD
TDHMGDIEVVAKAIRIKEILTSQGSLSHPIFVRRLRRLKCHVRVLAAGDQLPIMGSVLQVLYPWQLGDGKNNDSLVLYGR
LLNRTFLFTGDLEKEGENEIIKRYPQLRVDYLKAGHHGSNTSSSAAFLDHIQPKVAFISAGKNNRYQHPHRETLARLEDR
QITYYRTDTQGAIRLTGWTSWHLETVR

Nucleotide

• Length: 2244 bp

>NTDB_id=930829 ACB359_RS05365 WP_031488547.1 1078172..1080415(-) (comEC/celB) [Streptococcus pyogenes strain Isolate 16]
ATGACATTTTCTTGGACTAAGCTAGTGCCCCTGTCAAAGATTCAATTTGCTTTTTTAATCTTGGTTTTCTTTTATCAAAT
CCATAGCCCTAGCTGGTTAACGTTTCTCCTTAGCCTTAGTTTGATTTGCTTACTTGTCAAGCGTTTGTCTAAAAAAGAAT
TTCTCGGTGTCTTTGCCATCCTTAGTTTCTGTGCTTTGTTTTTGCTGTATCAGAAACAGCAGTTGGTTCAAAAACTGGAA
ATTCAGCCAGTACAAATAACCTCTGTAGCATTAGTTCCTGATAGTATTCGGATTAATGGTGATCAATTAGCTGTTCTTGG
ACGTCATGGGAAACATTCTTATCAGTTATTTTACCGTTTGAAAAGCCAAGCAGAAGCCCAATTGTTCAAGAAAGAGCACC
GTTGGTTAGTGATGCACGCAAAAGTGACATTGGAAAAAGCTGAGGAAGTTCGAAATTTTAAAGGCTTTAATTATCAGACT
TTTTTGGCTTATCAAGGAATTTACAGGATAGGGAAGGTAGAGCAAATAGAACAGCTTGAAGTGATTTCACCCGAGTCAAT
ATGTGACTATTTGTCCTCTTTAAGACGGCGAGCCATTGTTCATTGCCAGCAGCATTTTCCAAGACCTATGTCTCACTACC
TGACGGGCCTCCTTTTTGGTTATTTAGATAAGTCGTTTGGTGAGATGACAGATTATTATAGTCAGTTGGGTATCATTCAT
CTCTTTGCTTTATCAGGGATGCAGGTTGGCTTCTTTCTCACTTGTTTTAGAAGGGTGTTGCTATTACTCGCAGTTCCTTT
GGAATGGATAAAATGGATAGAGCTTCCTTTTGCTTCCTTTTATGCCGCGTTGACAGGTTATAGTATTTCTGTTATTCGAA
GCCTCGTGCAGTCGCAGTTGCGTCATTTAGGAATAAAAGGATTAGACAATCTGGCTTGTACTTTTTTACTTGTCTTTTTA
TGGGATGCTCATTTCTTAATGACTGTTGGTGGCGTATTAACGTTTAGCTATGCTTTTTTGTTAACAGTGGTTACTGTTGA
AGAATTATCAGGAGCTAAAAGACAGTTGGTACAAGTCTTGACCATTTCCCTAGGAATATTACCATTTTTGCTCTTTTATT
TTTCCAGTTTTAACCCCATGTCAATGGTCTTAACAGGGCTCTTGTCTTATCTCTTTGACCTTTTTATTTTGCCCCTTCTT
TGTCTGGTTTTTTGTCTATCCCCTTTGGTGACTGTCTCAATATGTAACCATCTTTTTATTTTATTAGAAAAAGTCATTCA
ATTTCTCGGAAATACTTTCAATAGTTCCCTTGTTTTTGGAAGCCCGACCAGTTGGCACTTGCTTATCTTGGTGATTAGCT
TCGCTATTTTTTATGATTATCGGCAGGTGCGACAACGAGTTATCACTTGCGGTTTGGTTATAGCGTTGACGCTTTTGTCT
GTCAAATATCCTTTGACCAATGAAGTGACCTTTATCGACATTGGCCAGGGAGATAGTATTTTGGTGAGGGAGTGGACAGG
GAAAAATCTCTTAATAGATGTAGGTGGGCGCCCTTTCTTTTCTTCAAAAGAGCACTGGCGACGAGAATATCACGTAGCTA
ATGCTCAGAAAACCTTAATTCCTTACTTAAAAAGTAGAGGTATTCACACAATTGACCAACTATTAGTAACTCACGCAGAT
ACTGATCATATGGGGGATATCGAAGTGGTTGCCAAAGCTATTCGGATAAAGGAGATTTTGACTAGTCAAGGCAGTTTAAG
CCATCCAATCTTTGTTAGGCGGCTAAGGCGTTTAAAATGTCACGTTAGGGTTTTAGCAGCTGGAGACCAGTTGCCTATTA
TGGGAAGTGTCTTACAGGTACTCTACCCTTGGCAGTTAGGGGACGGGAAAAATAACGATTCTTTGGTACTTTATGGCAGG
CTCTTAAATCGAACTTTTCTTTTCACAGGTGACTTGGAAAAAGAGGGGGAAAACGAGATCATAAAACGTTATCCTCAACT
AAGAGTAGATTATTTAAAAGCAGGTCACCATGGATCAAATACCTCTTCTAGTGCAGCTTTTTTAGACCATATTCAGCCTA
AAGTTGCCTTTATTTCTGCTGGAAAAAATAACCGTTATCAGCATCCTCACAGAGAAACCTTAGCCCGTTTGGAAGACAGA
CAAATTACTTATTACCGAACGGATACACAAGGAGCTATTCGTTTGACTGGTTGGACAAGCTGGCATCTTGAAACGGTCCG
TTAG

Domains

Predicted by InterProScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (495-701)

• Competence protein (Competence) (217-462)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	46.185	100	0.462
comEC/celB	Streptococcus mitis NCTC 12261	45.979	99.866	0.459
comEC/celB	Streptococcus pneumoniae TIGR4	44.98	100	0.45
comEC/celB	Streptococcus pneumoniae Rx1	44.786	100	0.448
comEC/celB	Streptococcus pneumoniae D39	44.786	100	0.448
comEC/celB	Streptococcus pneumoniae R6	44.786	100	0.448
comEC	Lactococcus lactis subsp. cremoris KW2	41.491	95.181	0.395