Detailed information    

insolico Bioinformatically predicted

Overview

Name   coiA   Type   Machinery gene
Locus tag   ACB355_RS06115 Genome accession   NZ_CP167011
Coordinates   1200188..1201150 (-) Length   320 a.a.
NCBI ID   WP_023078855.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Isolate 18     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1195188..1206150
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB355_RS06100 (ACB355_06100) - 1196024..1196731 (-) 708 WP_042765664.1 O-methyltransferase -
  ACB355_RS06105 (ACB355_06105) - 1196797..1197993 (-) 1197 WP_002995765.1 OFA family MFS transporter -
  ACB355_RS06110 (ACB355_06110) pepF 1198370..1200175 (-) 1806 WP_002995768.1 oligoendopeptidase F Regulator
  ACB355_RS06115 (ACB355_06115) coiA 1200188..1201150 (-) 963 WP_023078855.1 competence protein CoiA Machinery gene
  ACB355_RS06120 (ACB355_06120) - 1201445..1202161 (-) 717 WP_115224603.1 pseudouridine synthase -
  ACB355_RS06125 (ACB355_06125) nagB 1202265..1202978 (-) 714 WP_023078858.1 glucosamine-6-phosphate deaminase -
  ACB355_RS06130 (ACB355_06130) queA 1203180..1204208 (+) 1029 WP_023078839.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
  ACB355_RS06135 (ACB355_06135) - 1204215..1205435 (+) 1221 WP_023078850.1 DUF3114 domain-containing protein -

Sequence

Protein


Download         Length: 320 a.a.        Molecular weight: 37829.26 Da        Isoelectric Point: 10.2944

>NTDB_id=930642 ACB355_RS06115 WP_023078855.1 1200188..1201150(-) (coiA) [Streptococcus pyogenes strain Isolate 18]
MTKILTALDGRNQLISLVTQPISTKPPFRCPACKSPVRLRQGTIRRPHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLV
RTEAVCIEKYLPELQQIADLWVNDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTALQKQFLYFSS
SLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYSYQKKMTVNLSKRIQRALLARHP
KWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSGFCQIKGNLRPYYESFKVYYKKEKDKKVQTLFSPKYYVKMDSNRK

Nucleotide


Download         Length: 963 bp        

>NTDB_id=930642 ACB355_RS06115 WP_023078855.1 1200188..1201150(-) (coiA) [Streptococcus pyogenes strain Isolate 18]
GTGACAAAAATATTAACCGCTTTAGATGGTAGGAATCAGCTCATTTCGCTAGTAACTCAGCCTATTTCAACGAAACCGCC
TTTTCGTTGCCCAGCTTGCAAATCTCCTGTTCGCTTGCGTCAGGGGACAATTAGACGACCTCATTTTGCCCATGTACAAC
TAGCTCATTGTCAATTCCAAGCAGAAAATGAATCTGAGGAACATTTGACGTTGAAGGCAAAACTTTACACCAGTTTAGTC
CGAACAGAAGCTGTCTGTATTGAAAAATATCTTCCTGAGCTGCAACAGATAGCAGACCTTTGGGTGAATGATAAGTTAGC
CTTAGAAATTCAGTGCAGTCCCTTGCCAGTTGAGCGTCTAAAGAAACGCACCAAAGCTTATCAAGAAAAGGGGTATCCGG
TACGATGGTTACTGGGAAGAAAATTGTGGCTTAACACTCACTTAACTGCTTTGCAAAAACAGTTTCTTTACTTTTCATCT
AGTTTGGGCTTTCATTTGTGGGAGCTGGATGCAGCTGCAAATCTGCTACGTCTCAAATATTTAATCCATGAAGACTTATT
TGGTAAGGTAAGTTACCTAACAAAAACCATTTCTTTAGACCATAATATTATGGAAATGTTTCGGTTACCCTATCAGCAAG
AAATCCTTTATTCTTATCAGAAAAAAATGACTGTGAACCTATCTAAAAGAATACAAAGAGCTCTTTTAGCTAGACACCCG
AAATGGCTACGACGACAAGAAAAGGCTTACTTATCAGGCTATAATTTACTTATGTTAACAACTGATGCTTTTTATCCTCA
ATGGAGACCAGTTCAATCTTCCAGCGGTTTTTGTCAAATTAAAGGAAATCTTCGCCCTTATTATGAAAGTTTTAAAGTCT
ATTACAAAAAAGAAAAGGATAAGAAGGTGCAAACGCTTTTTTCACCAAAATATTATGTTAAAATGGATAGTAATAGAAAA
TGA

Domains

Predicted by InterProScan.

Competence protein CoiA-like family (CoiA_nuc)

(20-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  coiA Streptococcus mitis NCTC 12261

43.226

96.875

0.419
  coiA Streptococcus pneumoniae Rx1

41.935

96.875

0.406
  coiA Streptococcus pneumoniae D39

41.935

96.875

0.406
  coiA Streptococcus pneumoniae R6

41.935

96.875

0.406
  coiA Streptococcus pneumoniae TIGR4

41.935

96.875

0.406
  coiA Lactococcus lactis subsp. cremoris KW2

39.329

100

0.403