NTDB

Overview

Name	ruvA	Type	Machinery gene
Locus tag	ACB354_RS09445	Genome accession	NZ_CP167004
Coordinates	1819772..1820368 (-)	Length	198 a.a.
NCBI ID	WP_011185063.1	Uniprot ID	A2RGV1
Organism	Streptococcus pyogenes strain Isolate 28
Function	homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1814772..1825368

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB354_RS09410 (ACB354_09415)	-	1814833..1815138 (-)	306	WP_002982199.1	DUF1292 domain-containing protein	-
ACB354_RS09415 (ACB354_09420)	ruvX	1815150..1815569 (-)	420	WP_002982196.1	Holliday junction resolvase RuvX	-
ACB354_RS09420 (ACB354_09425)	-	1815566..1815835 (-)	270	WP_002982194.1	IreB family regulatory phosphoprotein	-
ACB354_RS09425 (ACB354_09430)	spx	1815948..1816346 (-)	399	WP_002982188.1	transcriptional regulator Spx	-
ACB354_RS09430 (ACB354_09435)	recA	1816637..1817773 (-)	1137	WP_002982186.1	recombinase RecA	Machinery gene
ACB354_RS09435 (ACB354_09440)	cinA	1817862..1819133 (-)	1272	WP_011185061.1	competence/damage-inducible protein A	Machinery gene
ACB354_RS09440 (ACB354_09445)	-	1819202..1819762 (-)	561	WP_021340449.1	DNA-3-methyladenine glycosylase I	-
ACB354_RS09445 (ACB354_09450)	ruvA	1819772..1820368 (-)	597	WP_011185063.1	Holliday junction branch migration protein RuvA	Machinery gene
ACB354_RS09450 (ACB354_09455)	-	1820370..1821590 (-)	1221	WP_011018316.1	MFS transporter	-
ACB354_RS09455 (ACB354_09460)	hexB	1821601..1823583 (-)	1983	WP_027968888.1	DNA mismatch repair endonuclease MutL	Machinery gene
ACB354_RS09460 (ACB354_09465)	-	1823678..1824829 (-)	1152	WP_023078125.1	site-specific integrase	-
ACB354_RS09465 (ACB354_09470)	-	1825151..1825294 (+)	144	WP_011185066.1	putative holin-like toxin	-

Sequence

Protein

Download Length: 198 a.a. Molecular weight: 21852.19 Da Isoelectric Point: 6.4948

                                >NTDB_id=930015 ACB354_RS09445 WP_011185063.1 1819772..1820368(-) (ruvA) [Streptococcus pyogenes strain Isolate 28]

MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI

GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL

LALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide

Download Length: 597 bp

                                >NTDB_id=930015 ACB354_RS09445 WP_011185063.1 1819772..1820368(-) (ruvA) [Streptococcus pyogenes strain Isolate 28]

ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT

GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAACTGGTAACTATTTACCTGCATCAAGTGATTCGTG

AGGATGCTCACTTGTTGTTTGGGTTTCATACGGAAGACGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGCATT

GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA

GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG

CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC

CTTGCCCTCGGTTATAAAGCAACAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAGCAATA

CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A2RGV1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ruvA	Streptococcus pneumoniae TIGR4	66.497	99.495	0.662
ruvA	Streptococcus pneumoniae R6	66.497	99.495	0.662
ruvA	Streptococcus pneumoniae D39	66.497	99.495	0.662
ruvA	Bacillus subtilis subsp. subtilis str. 168	40.394	100	0.414

Detailed information NTG0930015