Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK   Type   Regulator
Locus tag   VP472_RS05220 Genome accession   NZ_CP143632
Coordinates   1010966..1011544 (+) Length   192 a.a.
NCBI ID   WP_003155179.1    Uniprot ID   G1BIW7
Organism   Bacillus sp. MT(2024)     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1005966..1016544
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VP472_RS05200 (VP472_05200) - 1006466..1007758 (-) 1293 WP_024085090.1 globin-coupled sensor protein -
  VP472_RS05205 (VP472_05205) - 1007881..1009404 (-) 1524 WP_070081593.1 FAD-dependent oxidoreductase -
  VP472_RS05210 (VP472_05210) - 1009529..1010386 (+) 858 WP_007610477.1 SDR family oxidoreductase -
  VP472_RS05215 (VP472_05215) - 1010417..1010650 (-) 234 WP_003155181.1 IDEAL domain-containing protein -
  VP472_RS05220 (VP472_05220) comK 1010966..1011544 (+) 579 WP_003155179.1 competence protein ComK Regulator
  VP472_RS05225 (VP472_05225) - 1011690..1012058 (+) 369 WP_032874384.1 iron chaperone -
  VP472_RS05230 (VP472_05230) - 1012085..1012456 (+) 372 WP_070081594.1 iron chaperone -
  VP472_RS05235 (VP472_05235) - 1012589..1013299 (-) 711 WP_146276463.1 YrpD family protein -
  VP472_RS05240 (VP472_05240) - 1013495..1013764 (+) 270 WP_070081595.1 excalibur calcium-binding domain-containing protein -
  VP472_RS05245 (VP472_05245) - 1013797..1014114 (-) 318 WP_003155166.1 YbjQ family protein -
  VP472_RS05250 (VP472_05250) - 1014155..1015624 (-) 1470 WP_063174181.1 sodium:solute symporter -
  VP472_RS05255 (VP472_05255) - 1015621..1015821 (-) 201 WP_003155162.1 DUF3311 domain-containing protein -
  VP472_RS05260 (VP472_05260) - 1015942..1016301 (-) 360 WP_012117241.1 hypothetical protein -

Sequence

Protein


Download         Length: 192 a.a.        Molecular weight: 22315.58 Da        Isoelectric Point: 8.1419

>NTDB_id=930014 VP472_RS05220 WP_003155179.1 1010966..1011544(+) (comK) [Bacillus sp. MT(2024)]
MCQKTHAPLESYEVNRSTIAVLPEEIDGKMGSKVIEKDCILYVSMKPIHIIDRSCRYFGSSYAGRKAGTYEAIKISHKPP
IMVDPSNHIFLFPTLSSARPQCGWISHVHVKDFQPTAFDDTAVTFSNGKTMELEVSYHSFENQVYRTAYLRTTFQDRMGS
HIPKRQEFMLYPKEERTRMIYDFILRELGERY

Nucleotide


Download         Length: 579 bp        

>NTDB_id=930014 VP472_RS05220 WP_003155179.1 1010966..1011544(+) (comK) [Bacillus sp. MT(2024)]
ATGTGCCAGAAAACACACGCACCCTTAGAAAGCTACGAAGTAAATCGTTCAACCATCGCTGTTTTGCCTGAGGAAATAGA
CGGTAAAATGGGGTCGAAGGTCATTGAAAAAGACTGCATTCTGTATGTCAGCATGAAGCCGATTCACATCATCGACAGAA
GCTGCCGCTACTTTGGCTCCAGCTATGCCGGGAGAAAAGCAGGAACATATGAAGCGATTAAAATTTCTCACAAGCCGCCG
ATTATGGTGGACCCTTCAAATCACATCTTTTTATTCCCTACACTTTCTTCTGCAAGGCCTCAATGCGGCTGGATATCTCA
TGTGCACGTTAAAGATTTTCAACCGACGGCATTTGATGACACAGCGGTCACGTTCTCAAACGGCAAAACGATGGAACTGG
AAGTATCCTATCATTCTTTTGAAAATCAGGTTTACAGAACCGCCTATCTCAGAACCACTTTTCAGGACAGGATGGGCAGT
CATATCCCGAAGCGGCAGGAATTCATGCTGTATCCGAAAGAAGAGCGGACAAGAATGATCTACGACTTTATTTTGCGGGA
GCTGGGGGAGAGATATTAG

Domains

Predicted by InterproScan.

ComK protein (ComK)

(10-158)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G1BIW7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK Bacillus subtilis subsp. subtilis str. 168

82.292

100

0.823