Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   ACB350_RS06825 Genome accession   NZ_CP166999
Coordinates   1321999..1322664 (-) Length   221 a.a.
NCBI ID   WP_011054828.1    Uniprot ID   A0A0H2UVR9
Organism   Streptococcus pyogenes strain Isolate 34     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1316999..1327664
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB350_RS06820 (ACB350_06820) hpf 1321371..1321919 (-) 549 WP_002988974.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  ACB350_RS06825 (ACB350_06825) comFC/cflB 1321999..1322664 (-) 666 WP_011054828.1 ComF family protein Machinery gene
  ACB350_RS06830 (ACB350_06830) comFA/cflA 1322636..1323961 (-) 1326 WP_030127278.1 DEAD/DEAH box helicase Machinery gene
  ACB350_RS06835 (ACB350_06835) - 1324016..1324648 (+) 633 WP_002983676.1 YigZ family protein -
  ACB350_RS06840 (ACB350_06840) cysK 1324776..1325717 (+) 942 WP_002991877.1 cysteine synthase A -
  ACB350_RS06845 (ACB350_06845) - 1325735..1326112 (-) 378 WP_002991882.1 S1 RNA-binding domain-containing protein -
  ACB350_RS06850 (ACB350_06850) - 1326112..1327512 (-) 1401 WP_011054832.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25133.39 Da        Isoelectric Point: 9.4626

>NTDB_id=929505 ACB350_RS06825 WP_011054828.1 1321999..1322664(-) (comFC/cflB) [Streptococcus pyogenes strain Isolate 34]
MICLLCQQISQTPIGITEIIFLRRISSPICQQCQKSFQKIGKSVCATCCANSDIIACRDCLKWENKGYNVNHRSLYCYNA
AMKAYFSQYKFQGDYLLRKVFAVELADVITKYYKGYIPVPVPVSPGCFRERQFNQVSAILEAANVSYLSLFEKLDNTHQS
SRTKKERLLVEKSYRLLKVSNIPDKILIVDDIYTTGSTIIALRKQLAKVANSDIKSLSIAR

Nucleotide


Download         Length: 666 bp        

>NTDB_id=929505 ACB350_RS06825 WP_011054828.1 1321999..1322664(-) (comFC/cflB) [Streptococcus pyogenes strain Isolate 34]
ATGATCTGTCTACTATGTCAACAAATTAGTCAAACACCAATAGGTATTACAGAAATCATCTTTTTAAGGCGTATCTCTTC
ACCGATTTGTCAACAATGTCAAAAAAGCTTTCAAAAGATAGGAAAAAGTGTTTGTGCGACATGTTGTGCAAACTCAGATA
TAATAGCTTGTCGAGATTGTCTAAAATGGGAAAACAAAGGATACAATGTAAATCATAGAAGCTTATATTGTTATAATGCT
GCTATGAAAGCATACTTCAGTCAATATAAGTTTCAAGGAGACTATTTATTAAGAAAAGTTTTTGCAGTAGAACTTGCCGA
TGTTATCACCAAGTACTATAAAGGCTATATCCCAGTCCCGGTTCCTGTAAGTCCCGGTTGTTTTCGAGAAAGACAATTTA
ATCAAGTGAGCGCTATTCTTGAGGCAGCTAATGTTAGCTACCTTTCTCTTTTTGAAAAGCTAGATAATACTCACCAATCT
TCCAGAACAAAAAAAGAGAGATTATTAGTAGAAAAATCTTATCGACTACTAAAAGTATCAAACATTCCTGATAAAATCCT
TATAGTAGATGATATTTATACTACTGGTAGTACAATTATCGCTCTTAGAAAACAATTGGCTAAAGTAGCAAATAGTGATA
TTAAAAGTTTGTCAATTGCACGTTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UVR9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae Rx1

41.629

100

0.416
  comFC/cflB Streptococcus pneumoniae D39

41.629

100

0.416
  comFC/cflB Streptococcus pneumoniae R6

41.629

100

0.416
  comFC/cflB Streptococcus pneumoniae TIGR4

41.629

100

0.416
  comFC/cflB Streptococcus mitis SK321

41.629

100

0.416
  comFC/cflB Streptococcus mitis NCTC 12261

41.176

100

0.412