Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   VKP38_RS07685 Genome accession   NZ_CP142352
Coordinates   1530791..1531477 (-) Length   228 a.a.
NCBI ID   WP_002991052.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 2907-97     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1525791..1536477
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP38_RS07665 (VKP38_07665) - 1526154..1527329 (-) 1176 WP_031488562.1 replication initiation and membrane attachment family protein -
  VKP38_RS07670 (VKP38_07670) nrdR 1527313..1527807 (-) 495 WP_002985941.1 transcriptional regulator NrdR -
  VKP38_RS07675 (VKP38_07675) - 1527981..1529049 (-) 1069 Protein_1464 ISAs1 family transposase -
  VKP38_RS07680 (VKP38_07680) covS 1529283..1530785 (-) 1503 WP_002991036.1 two-component system sensor histidine kinase CovS -
  VKP38_RS07685 (VKP38_07685) covR 1530791..1531477 (-) 687 WP_002991052.1 two-component system response regulator CovR Regulator
  VKP38_RS07690 (VKP38_07690) - 1531744..1532277 (-) 534 WP_032464180.1 YceD family protein -
  VKP38_RS07695 (VKP38_07695) htpX 1532511..1533407 (-) 897 WP_063629345.1 zinc metalloprotease HtpX -
  VKP38_RS07700 (VKP38_07700) - 1533454..1534011 (-) 558 WP_002985956.1 LemA family protein -
  VKP38_RS07705 (VKP38_07705) rsmG 1534161..1534874 (+) 714 WP_063629344.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  VKP38_RS07710 (VKP38_07710) ktrB 1534959..1536335 (+) 1377 WP_032459855.1 potassium uptake transporter channel subunit KtrB -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26618.70 Da        Isoelectric Point: 4.6586

>NTDB_id=925123 VKP38_RS07685 WP_002991052.1 1530791..1531477(-) (covR) [Streptococcus pyogenes strain 2907-97]
MTKKILIIEDEKNLARFVSLELQHEGYEVIVEVNGREGLETALEKEFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKVPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=925123 VKP38_RS07685 WP_002991052.1 1530791..1531477(-) (covR) [Streptococcus pyogenes strain 2907-97]
ATGACAAAGAAAATTTTAATTATTGAAGATGAAAAGAATCTGGCTAGATTCGTTTCTCTTGAGCTGCAACATGAGGGTTA
TGAAGTCATTGTTGAGGTCAATGGTCGCGAAGGGTTAGAAACTGCTTTGGAAAAAGAGTTTGATTTAATCCTGCTTGACT
TAATGTTACCAGAGATGGATGGTTTTGAAGTGACCCGTCGTTTGCAAACCGAAAAAACAACGTATATCATGATGATGACT
GCGCGTGATTCTATTATGGATGTGGTTGCAGGTTTAGACCGCGGTGCAGACGACTATATTGTTAAACCGTTTGCCATTGA
AGAACTACTTGCCCGTATTCGTGCTATTTTCCGCCGTCAAGATATTGAATCTGAGAAGAAAGTGCCTAGTCAAGGTATTT
ATCGAGATCTAGTTTTAAATCCACAAAACCGTTCAGTTAATCGTGGCGACGATGAGATTTCTCTCACTAAACGTGAATAT
GATTTGCTTAATATTTTGATGACTAATATGAATCGTGTCATGACACGTGAAGAATTATTGTCAAATGTTTGGAAATATGA
TGAAGCCGTTGAGACTAATGTTGTAGATGTCTATATTCGTTATCTCCGCGGCAAAATTGACATTCCAGGCAAGGAATCTT
ATATCCAAACAGTGCGTGGCATGGGATACGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.096

100

0.825
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.96

99.561

0.667
  vicR Streptococcus mutans UA159

43.966

100

0.447
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425