Detailed information NTG0924999

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: VKP56_RS04615
• Genome accession: NZ_CP142350
• Coordinates: 926480..927790 (-)
• Length: 436 a.a.
• NCBI ID: WP_023610011.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain SS1445
• Function: Required for optimal comC expression (predicted from homology) Competence regulation

Genomic Context

Location: 921480..932790

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP56_RS04590 (VKP56_04590)	-	922084..923136 (-)	1053	WP_326656461.1	BMP family protein	-
VKP56_RS04595 (VKP56_04595)	-	923230..923619 (-)	390	WP_011285547.1	cytidine deaminase	-
VKP56_RS04600 (VKP56_04600)	-	924272..924865 (-)	594	WP_010922352.1	class I SAM-dependent methyltransferase	-
VKP56_RS04605 (VKP56_04605)	coaA	925133..926053 (+)	921	WP_010922353.1	type I pantothenate kinase	-
VKP56_RS04610 (VKP56_04610)	rpsT	926107..926355 (+)	249	WP_009881183.1	30S ribosomal protein S20	-
VKP56_RS04615 (VKP56_04615)	ciaH	926480..927790 (-)	1311	WP_023610011.1	sensor histidine kinase	Regulator
VKP56_RS04620 (VKP56_04620)	ciaR	927783..928457 (-)	675	WP_002984519.1	response regulator transcription factor	Regulator
VKP56_RS04625 (VKP56_04625)	-	928803..931340 (-)	2538	WP_136076803.1	M1 family metallopeptidase	-
VKP56_RS04630 (VKP56_04630)	phoU	931545..932198 (-)	654	WP_002984514.1	phosphate signaling complex protein PhoU	-

Sequence

Protein

• Length: 436 a.a.
• Molecular weight: 50065.56 Da
• Isoelectric Point: 9.0837

>NTDB_id=924999 VKP56_RS04615 WP_023610011.1 926480..927790(-) (ciaH) [Streptococcus pyogenes strain SS1445]
MNKLKKEILSDNYNHFFHFFAVFTGIFVIMTIIILQIMRFGVYSSVDSSLVSVSNNASSYANRTMARISSFYFDTENNII
KALPDSDSSKLLGTPAANTDIILFSANGTILNAFDAFSNYQNFHLDKHRLGSIETTSLMNFYGQEEKYHTITVRVHIKNY
PAVAYMMAVVNVEQLDRANERYERIIIIVMSVFWLISILASIYLAKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTHLDTDFFNAIFENYELVAKEYGKIFYFQN
QVNRSLRMDKALLKQLITILFDNAIKYTDKNGIIEIIAKTTDKNLLISVIDNGPGITDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVMSLKGNITVKDNDPKGSIFEVKL

Nucleotide

• Length: 1311 bp

>NTDB_id=924999 VKP56_RS04615 WP_023610011.1 926480..927790(-) (ciaH) [Streptococcus pyogenes strain SS1445]
ATGAATAAATTAAAAAAAGAGATTTTATCAGATAACTATAACCACTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTCATTATGACTATTATTATCTTACAGATTATGCGGTTTGGCGTTTATTCGTCAGTTGACAGTAGTTTAGTTTCTGTTA
GTAATAATGCAAGTAGTTATGCTAATCGTACGATGGCTAGAATATCTTCTTTTTACTTTGATACTGAAAATAACATTATT
AAGGCGCTGCCTGATTCAGATAGTTCTAAGTTATTAGGAACGCCTGCAGCTAATACAGATATCATTTTGTTTAGTGCTAA
TGGAACAATTTTAAATGCTTTTGATGCGTTTTCTAACTATCAAAATTTTCATTTAGATAAACACCGTTTGGGGAGTATTG
AAACCACCAGTTTAATGAATTTTTATGGACAAGAAGAAAAATACCATACGATAACTGTAAGGGTTCATATCAAAAATTAT
CCTGCAGTTGCCTATATGATGGCAGTAGTAAATGTGGAACAATTAGACCGCGCTAATGAACGTTACGAGCGCATTATTAT
TATAGTTATGAGTGTTTTTTGGCTAATTTCTATTTTAGCAAGTATTTATTTAGCCAAGTGGAGCAGAAAACCTATTTTAG
AAAGCTATGAAAAACAAAAAATGTTTGTTGAAAATGCTAGTCATGAACTAAGGACCCCTTTGGCGGTCTTACAGAATCGT
CTGGAATCGCTTTTTCGTAAGCCCAACGAAACGATATTAGAAAATAGTGAGCATCTCGCTTCTAGTTTAGACGAGGTTCG
CAACATGCGCATCTTAACAACTAATTTATTAAATTTAGCAAGACGAGATGATGGCATTAATCCACAGTGGACTCATTTAG
ATACAGATTTTTTTAATGCTATTTTTGAGAATTATGAACTAGTTGCTAAAGAATATGGAAAAATATTTTATTTTCAGAAC
CAAGTCAATAGATCGTTAAGAATGGATAAGGCTTTACTAAAACAATTAATAACGATTTTATTTGACAATGCTATTAAATA
TACAGATAAAAATGGTATTATTGAAATTATAGCGAAAACAACGGACAAAAATTTATTAATTTCTGTTATTGATAATGGTC
CAGGGATAACAGATGAAGAAAAGAAAAAGATTTTTGATCGTTTTTATCGAGTTGACAAAGCTAGAACACGGCAAACAGGT
GGATTTGGCTTGGGGTTGGCTTTAGCTCAGCAAATCGTGATGTCTTTAAAAGGAAATATTACAGTAAAGGATAATGATCC
TAAAGGTAGTATTTTTGAAGTCAAACTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (329-436)

• His Kinase A (phospho-acceptor) domain (HisKA) (220-285)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus mutans UA159	57.666	100	0.578
ciaH	Streptococcus pneumoniae Rx1	51.37	100	0.516
ciaH	Streptococcus pneumoniae D39	51.37	100	0.516
ciaH	Streptococcus pneumoniae R6	51.37	100	0.516
ciaH	Streptococcus pneumoniae TIGR4	51.37	100	0.516