Detailed information NTG0921022

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: VOI49_RS05575
• Genome accession: NZ_CP142018
• Coordinates: 1091998..1093308 (-)
• Length: 436 a.a.
• NCBI ID: WP_115252901.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae strain lu24
• Function: Required for optimal comC expression (predicted from homology) Competence regulation

Genomic Context

Location: 1086998..1098308

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VOI49_RS05545	-	1087432..1087821 (-)	390	WP_324738702.1	cytidine deaminase	-
VOI49_RS05550	deoC	1087808..1088470 (-)	663	WP_226313921.1	deoxyribose-phosphate aldolase	-
VOI49_RS05555	-	1088486..1089763 (-)	1278	WP_003050932.1	pyrimidine-nucleoside phosphorylase	-
VOI49_RS05560	-	1089750..1090349 (-)	600	WP_037584951.1	class I SAM-dependent methyltransferase	-
VOI49_RS05565	coaA	1090618..1091538 (+)	921	WP_003050936.1	type I pantothenate kinase	-
VOI49_RS05570	rpsT	1091592..1091840 (+)	249	WP_009881183.1	30S ribosomal protein S20	-
VOI49_RS05575	ciaH	1091998..1093308 (-)	1311	WP_115252901.1	sensor histidine kinase	Regulator
VOI49_RS05580	ciaR	1093301..1093975 (-)	675	WP_003050941.1	response regulator transcription factor	Regulator
VOI49_RS05585	-	1094180..1096717 (-)	2538	WP_003050944.1	M1 family metallopeptidase	-
VOI49_RS05590	phoU	1096917..1097570 (-)	654	WP_003050946.1	phosphate signaling complex protein PhoU	-

Sequence

Protein

• Length: 436 a.a.
• Molecular weight: 49834.38 Da
• Isoelectric Point: 8.2353

>NTDB_id=921022 VOI49_RS05575 WP_115252901.1 1091998..1093308(-) (ciaH) [Streptococcus dysgalactiae strain lu24]
MNKLKKEVLSDQYTHFFHFFAVFTGIFVVMTIIILQIMRFGVYSSVDSSLISVSNNASSYANRTMARISSFYFDAENNVI
KPLPDSDNSKLVGTPAANTDIILFSANGTILNSFDAFSNYQNFHLDKRQLGTIVTTSLMNFYGQEEKYHTITVRVHIRNY
PAVAYMMAVVNVEQLDSANERYEQIIIIVMIIFWLISILASIYLSKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTDLDATFFDAVFENYQLVAEENGKVFLFEN
QVNRTLKMDKALLKQLMTILFDNAIKYTDKEGVVDIKVKTTEKNLLISVIDNGPGIKDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVISLKGSISVKDNLPKGSIFEVKL

Nucleotide

• Length: 1311 bp

>NTDB_id=921022 VOI49_RS05575 WP_115252901.1 1091998..1093308(-) (ciaH) [Streptococcus dysgalactiae strain lu24]
ATGAATAAATTAAAAAAAGAAGTCCTCTCTGATCAATACACCCATTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTTGTGATGACCATCATTATTTTGCAGATTATGCGATTTGGTGTGTATTCTTCTGTCGATAGTAGTCTGATTTCTGTTA
GTAATAATGCAAGCAGTTATGCCAATCGTACTATGGCTAGAATATCTTCTTTTTACTTTGATGCAGAAAATAATGTCATT
AAACCTTTGCCTGATTCAGACAATTCAAAGTTAGTAGGAACACCGGCGGCAAATACAGATATTATCCTATTTAGTGCCAA
TGGCACAATTTTGAATTCCTTTGATGCTTTTTCCAATTATCAAAATTTTCATTTAGACAAGCGACAATTAGGGACGATTG
TTACCACTAGCCTGATGAATTTTTACGGTCAAGAGGAGAAGTATCATACCATAACAGTAAGGGTTCATATTAGAAATTAC
CCAGCTGTGGCATATATGATGGCAGTTGTCAACGTTGAGCAGTTGGACAGTGCCAACGAACGCTACGAACAAATTATTAT
CATTGTGATGATTATCTTCTGGTTAATTTCTATTTTGGCAAGTATTTATTTGTCCAAGTGGAGTCGAAAGCCGATTTTGG
AAAGTTACGAAAAACAAAAAATGTTTGTGGAAAATGCCAGTCATGAATTAAGAACCCCATTGGCTGTTTTGCAAAATCGC
TTAGAGTCCCTTTTCCGGAAGCCTAATGAAACCATATTGGAAAATAGTGAACATTTGGCTTCGAGTCTAGATGAAGTTCG
AAATATGCGTATTTTAACAACTAATCTCTTAAATTTAGCAAGACGTGACGATGGGATCAACCCCCAGTGGACTGACCTGG
ACGCTACCTTTTTTGATGCTGTTTTTGAGAATTATCAGCTAGTTGCTGAAGAAAATGGCAAGGTATTTCTTTTCGAAAAT
CAAGTTAACCGCACCTTGAAAATGGACAAGGCTCTTTTGAAGCAATTGATGACGATTTTATTTGATAATGCGATTAAATA
CACGGATAAAGAAGGCGTTGTTGACATTAAGGTCAAGACAACAGAGAAAAATCTCTTGATTTCAGTCATTGATAACGGTC
CAGGAATTAAAGATGAGGAAAAGAAAAAGATTTTTGACCGTTTTTATCGCGTTGATAAAGCTAGAACCCGTCAGACTGGA
GGCTTTGGCTTAGGCTTAGCTTTAGCTCAACAGATTGTGATATCACTCAAAGGAAGTATCAGCGTTAAGGATAACCTTCC
TAAGGGTAGTATCTTTGAAGTCAAACTATAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (220-285)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (329-436)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus mutans UA159	58.352	100	0.585
ciaH	Streptococcus pneumoniae Rx1	51.598	100	0.518
ciaH	Streptococcus pneumoniae D39	51.598	100	0.518
ciaH	Streptococcus pneumoniae R6	51.598	100	0.518
ciaH	Streptococcus pneumoniae TIGR4	51.598	100	0.518