Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   VOI49_RS03195 Genome accession   NZ_CP142018
Coordinates   594929..595636 (+) Length   235 a.a.
NCBI ID   WP_003049966.1    Uniprot ID   A0A380JXI0
Organism   Streptococcus dysgalactiae strain lu24     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 589929..600636
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VOI49_RS03170 ftsY 590490..592040 (+) 1551 WP_003049960.1 signal recognition particle-docking protein FtsY -
  VOI49_RS03175 - 592166..592981 (-) 816 WP_003049961.1 TIGR03943 family putative permease subunit -
  VOI49_RS03180 - 592981..593883 (-) 903 WP_003049962.1 permease -
  VOI49_RS03185 - 594030..594185 (-) 156 WP_164549214.1 SPJ_0845 family protein -
  VOI49_RS03190 - 594366..594842 (+) 477 WP_037585091.1 cupin domain-containing protein -
  VOI49_RS03195 vicR 594929..595636 (+) 708 WP_003049966.1 response regulator transcription factor Regulator
  VOI49_RS03200 pnpS 595637..596965 (+) 1329 WP_226317210.1 two-component system histidine kinase PnpS -
  VOI49_RS03205 - 597132..598007 (+) 876 WP_226313591.1 substrate-binding domain-containing protein -
  VOI49_RS03210 pstC 598125..598988 (+) 864 WP_003060511.1 phosphate ABC transporter permease subunit PstC -
  VOI49_RS03215 pstA 598981..599796 (+) 816 WP_324739403.1 phosphate ABC transporter permease PstA -
  VOI49_RS03220 pstB 599798..600550 (+) 753 WP_324739404.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27549.78 Da        Isoelectric Point: 5.7025

>NTDB_id=921015 VOI49_RS03195 WP_003049966.1 594929..595636(+) (vicR) [Streptococcus dysgalactiae strain lu24]
MTKQILLVDDEEHILRLLDYHLSKEGFSTQLVTDGRKALTLAETEPFDFILLDIMLPRLDGIEVCKRLRAKAIKTPIMMV
SAKSDEFDKVLALELGADDYLTKPFSPRELVARVKAILRRTSKEQQEDDTDDFRDDYRVFGALTVYPDRHEVYKADHLLS
LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLRDKIEDNPKDPQFIQTIRGYGYKFKEL

Nucleotide


Download         Length: 708 bp        

>NTDB_id=921015 VOI49_RS03195 WP_003049966.1 594929..595636(+) (vicR) [Streptococcus dysgalactiae strain lu24]
ATGACAAAACAAATCTTATTAGTGGATGATGAAGAACATATTTTGAGGCTACTGGATTATCATCTCAGTAAAGAAGGTTT
TTCCACACAATTGGTAACAGATGGACGAAAAGCATTGACATTGGCAGAAACAGAGCCTTTTGACTTTATCCTACTTGATA
TTATGTTGCCTCGGTTAGACGGCATAGAAGTGTGTAAGCGACTAAGAGCTAAAGCTATTAAAACTCCGATTATGATGGTT
TCTGCTAAAAGTGATGAATTTGATAAGGTTTTGGCCTTGGAATTAGGAGCTGATGATTACCTGACAAAGCCTTTTAGCCC
TAGGGAATTAGTAGCTCGTGTCAAGGCTATTTTACGGCGAACCAGTAAAGAGCAGCAAGAAGATGACACAGATGATTTCA
GGGATGATTATCGGGTATTTGGGGCCCTAACCGTCTATCCAGACCGGCATGAGGTTTATAAGGCAGATCATTTATTGAGC
CTTACCCCAAAGGAATTTGAACTCTTACTCTATCTTATGAAACATCCCAACATGACCTTAACTAGGGAACGTTTACTTGA
ACGGATTTGGGGATATGATTTTGGACAAGAAACCCGTTTAGTGGATGTTCATATTGGCAAATTGAGAGATAAGATAGAGG
ATAACCCTAAAGACCCTCAATTTATTCAAACGATTAGAGGCTATGGGTATAAGTTTAAGGAGTTATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(159-232)

Response regulator receiver domain (Response_reg)

(5-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380JXI0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

48.718

99.574

0.485
  micA Streptococcus pneumoniae Cp1015

48.246

97.021

0.468
  covR Lactococcus lactis subsp. lactis strain DGCC12653

40.851

100

0.409
  covR Streptococcus salivarius strain HSISS4

40.084

100

0.404