Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   VOI49_RS02135 Genome accession   NZ_CP142018
Coordinates   394820..395506 (+) Length   228 a.a.
NCBI ID   WP_003049736.1    Uniprot ID   A0A9X5LVW0
Organism   Streptococcus dysgalactiae strain lu24     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 389820..400506
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VOI49_RS02110 ktrB 389928..391304 (-) 1377 WP_226313641.1 TrkH family potassium uptake protein -
  VOI49_RS02115 rsmG 391388..392101 (-) 714 WP_115246663.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  VOI49_RS02120 - 392254..392811 (+) 558 WP_324739292.1 LemA family protein -
  VOI49_RS02125 htpX 392856..393749 (+) 894 WP_003049732.1 zinc metalloprotease HtpX -
  VOI49_RS02130 - 394016..394549 (+) 534 WP_226313671.1 YceD family protein -
  VOI49_RS02135 covR 394820..395506 (+) 687 WP_003049736.1 two-component system response regulator CovR Regulator
  VOI49_RS02140 - 395512..397011 (+) 1500 WP_324739294.1 HAMP domain-containing histidine kinase -
  VOI49_RS02145 nrdR 397218..397712 (+) 495 WP_003049740.1 transcriptional regulator NrdR -
  VOI49_RS02150 - 397696..398874 (+) 1179 WP_080555670.1 DnaD domain protein -
  VOI49_RS02155 dnaI 398875..399777 (+) 903 WP_003049744.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26567.56 Da        Isoelectric Point: 4.6541

>NTDB_id=921008 VOI49_RS02135 WP_003049736.1 394820..395506(+) (covR) [Streptococcus dysgalactiae strain lu24]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKTPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
DLLSILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=921008 VOI49_RS02135 WP_003049736.1 394820..395506(+) (covR) [Streptococcus dysgalactiae strain lu24]
ATGACAAAGAAAATTTTAATTATTGAAGATGAAAAGAACCTTGCACGGTTCGTTTCACTCGAATTGCAACATGAAGGTTA
CGAAGTAACTGTTGAAGTAAATGGTCGCGAAGGTTTAGAAACTGCCTTAGAAAAAGATTTTGACTTAATCCTCCTTGACC
TAATGCTTCCTGAAATGGATGGTTTTGAAGTGACTCGTCGCTTACAAACTGAAAAAACAACTTACATTATGATGATGACT
GCGCGTGATTCGATTATGGATGTGGTTGCGGGGTTAGACCGTGGAGCGGATGATTACATTGTGAAGCCATTTGCAATTGA
AGAGTTATTGGCTCGTATCCGTGCCATTTTCCGTCGCCAAGATATCGAATCTGAGAAGAAGACCCCTAGTCAAGGGATTT
ACCGTGATTTGGTCTTGAACCCACAAAACCGTTCAGTTAACAGAGGAGATGATGAAATCTCTTTGACGAAACGTGAATAT
GATTTGCTTAGCATTTTGATGACTAATATGAATCGTGTCATGACACGTGAAGAGTTATTGTCAAATGTTTGGAAATACGA
TGAAGCTGTTGAAACAAATGTAGTGGATGTTTATATTCGTTACCTTCGCGGCAAAATCGATATTCCAGGTAAGGAGTCTT
ATATCCAAACCGTTCGCGGTATGGGCTATGTTATTCGTGAGAAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.096

100

0.825
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.401

99.561

0.671
  vicR Streptococcus mutans UA159

43.723

100

0.443
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425