Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   VA609_RS08765 Genome accession   NZ_CP142012
Coordinates   1911166..1912500 (+) Length   444 a.a.
NCBI ID   WP_324739184.1    Uniprot ID   -
Organism   Pasteurella multocida strain PM-2     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1906166..1917500
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VA609_RS08740 (VA609_08740) - 1906312..1908873 (-) 2562 WP_005754757.1 penicillin-binding protein 1A -
  VA609_RS08745 (VA609_08745) - 1909009..1909782 (+) 774 Protein_1688 competence protein ComA -
  VA609_RS08750 (VA609_08750) - 1909822..1910253 (+) 432 WP_324739183.1 competence protein ComB -
  VA609_RS08755 (VA609_08755) - 1910267..1910791 (+) 525 WP_061406403.1 hypothetical protein -
  VA609_RS08760 (VA609_08760) - 1910794..1911156 (+) 363 WP_014668625.1 pilus assembly protein PilP -
  VA609_RS08765 (VA609_08765) comE 1911166..1912500 (+) 1335 WP_324739184.1 type IV pilus secretin PilQ Machinery gene
  VA609_RS08770 (VA609_08770) aroK 1912683..1913210 (+) 528 WP_005717623.1 shikimate kinase AroK -
  VA609_RS08775 (VA609_08775) aroB 1913227..1914315 (+) 1089 WP_324739185.1 3-dehydroquinate synthase -
  VA609_RS08780 (VA609_08780) - 1914319..1915224 (+) 906 WP_005723696.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -
  VA609_RS08785 (VA609_08785) - 1915271..1915576 (-) 306 WP_005723691.1 DUF721 domain-containing protein -
  VA609_RS08790 (VA609_08790) secM 1915669..1915980 (+) 312 WP_005723689.1 secA translation cis-regulator SecM -

Sequence

Protein


Download         Length: 444 a.a.        Molecular weight: 49298.68 Da        Isoelectric Point: 7.6666

>NTDB_id=920911 VA609_RS08765 WP_324739184.1 1911166..1912500(+) (comE) [Pasteurella multocida strain PM-2]
MWRAFRKISFVYFLCGVAYVGSSQAQDAEHFYLRLKQAPLVEMLQYLALQQHQDLLIDDHLEGTLSLQMKKTTFEKCLQS
IARMKQLELHQEGKSYYLTSPSGVAENDTHHPTSLMTSSIKLHFAKAAEVVKSLTSGQGSLLSVGGSLSFDERTNLLLIQ
DEPQSIQRIKALVAEMDKPIEQIAIEARIVTMTDESLQELGVRWGLFQATEQAHTIAGSLAANGFSNIENQLNVNFSTNS
APVGSIALQLAKINGRLLDLELTALEREKHIEIIASPRLLTTNKKSASIKQGTEIPYVMKRGKDKSESVEFREAVLGLDV
TPHISKDNTILLDLLITQNTLGAPVVYDKGEIVSIDKQEINTQVVAQDGETIVLGGVFHDTMTKGVNKVPLLGDLPLLKH
VFSQKTERHQKRELVIFVTPHIIKPSQGSPEQKTTRVKKSAKSR

Nucleotide


Download         Length: 1335 bp        

>NTDB_id=920911 VA609_RS08765 WP_324739184.1 1911166..1912500(+) (comE) [Pasteurella multocida strain PM-2]
ATGTGGCGAGCATTCAGAAAAATATCTTTTGTGTACTTTTTATGTGGGGTTGCTTATGTTGGAAGTAGTCAAGCACAAGA
CGCAGAACATTTTTATTTACGTTTAAAACAAGCGCCTTTAGTTGAAATGTTACAGTATTTAGCATTGCAACAACATCAGG
ATTTGTTAATCGATGATCATTTAGAGGGCACATTATCATTACAGATGAAAAAGACAACCTTTGAGAAATGTTTACAGTCG
ATTGCAAGAATGAAACAACTTGAGTTACATCAAGAAGGAAAATCCTATTATTTAACTTCCCCTTCAGGTGTTGCAGAAAA
CGATACTCATCATCCTACGTCATTGATGACATCTTCAATAAAATTGCATTTTGCCAAAGCGGCAGAGGTGGTGAAATCTT
TAACTTCAGGGCAGGGAAGTTTACTTTCTGTCGGGGGGAGTTTGAGTTTTGATGAGCGGACTAATTTACTGCTGATTCAG
GATGAACCGCAATCAATACAGCGTATTAAAGCATTAGTAGCAGAAATGGATAAACCCATTGAACAAATTGCGATCGAAGC
TAGGATTGTGACGATGACAGACGAAAGTTTGCAGGAACTTGGTGTAAGATGGGGGCTATTTCAAGCAACAGAACAGGCAC
ATACTATTGCGGGGAGTTTAGCCGCGAACGGCTTTTCGAATATAGAAAACCAATTAAATGTGAATTTCTCGACCAATAGT
GCACCTGTTGGTTCCATCGCCTTACAGTTGGCGAAAATAAATGGTCGATTATTAGACTTGGAATTAACTGCCTTGGAGCG
AGAAAAGCATATTGAGATTATTGCGAGTCCTCGTTTATTAACAACGAATAAAAAAAGTGCCAGTATCAAACAAGGGACAG
AAATTCCTTATGTGATGAAACGGGGAAAAGATAAAAGCGAATCGGTGGAATTTCGAGAAGCTGTATTAGGTTTAGATGTG
ACACCGCATATCTCAAAAGACAACACGATTTTATTAGATTTATTGATTACACAAAATACATTAGGTGCACCGGTAGTGTA
TGATAAAGGCGAAATTGTTTCGATCGATAAACAGGAAATCAATACTCAAGTCGTCGCTCAAGATGGTGAAACCATCGTTT
TAGGTGGGGTGTTTCATGATACGATGACAAAGGGAGTCAATAAAGTACCATTACTAGGGGATTTGCCTTTGCTTAAACAT
GTGTTTAGCCAAAAAACTGAACGTCATCAAAAGCGGGAATTAGTGATTTTTGTCACTCCTCATATTATCAAACCTAGCCA
AGGTTCGCCTGAACAAAAAACAACAAGAGTTAAAAAATCTGCAAAATCGAGGTGA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(264-424)

Bacterial type II/III secretion system short domain (Secretin_N)

(119-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

62.037

97.297

0.604
  comE Haemophilus influenzae 86-028NP

61.343

97.297

0.597
  comE Glaesserella parasuis strain SC1401

48.961

97.523

0.477
  pilQ Vibrio campbellii strain DS40M4

40.189

95.27

0.383
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

40.241

93.468

0.376
  pilQ Vibrio cholerae strain A1552

40.241

93.468

0.376